在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Human Thrombospondin type-1 domain-containing protein 4(THSD4) ELISA kit

Human Thrombospondin type-1 domain-containing protein 4(THSD4) ELISA kit

  • 中文名稱：
    人血小板反應(yīng)素1型結(jié)構(gòu)域蛋白4(THSD4)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-EL023518HU
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    人血小板反應(yīng)素1型結(jié)構(gòu)域蛋白4(THSD4)酶聯(lián)免疫試劑盒（CSB-EL023518HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織培養(yǎng)上清液、組織勻漿樣本中的THSD4含量。THSD4是一種預(yù)測具有水解酶活性和細胞外基質(zhì)結(jié)構(gòu)成分的蛋白，可能在彈性纖維組件中起作用，位于含膠原蛋白的細胞外基質(zhì)和細胞外外泌體中。其研究機制涉及遺傳性血小板病，如巨血小板綜合征和血小板無力癥，以及其在止血、炎癥和免疫反應(yīng)中的作用。試劑盒檢測范圍為12.5 pg/mL-800 pg/mL，該產(chǎn)品適用于基礎(chǔ)研究中對THSD4表達水平的定量分析，如探究其在心血管疾病、纖維化病變或腫瘤進展中的分子機制，亦可用于體外培養(yǎng)細胞模型中THSD4分泌水平的動態(tài)監(jiān)測。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    THSD4 ELISA Kit; UNQ9334/PRO34005 ELISA Kit; Thrombospondin type-1 domain-containing protein 4 ELISA Kit; A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6 ELISA Kit; ADAMTS-like protein 6 ELISA Kit; ADAMTSL-6 ELISA Kit
  • 縮寫：
    THSD4
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, cell culture supernates, tissue homogenates
  • 檢測范圍：
    12.5 pg/mL-800 pg/mL
  • 靈敏度：
    3.12 pg/mL
  • 反應(yīng)時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Signal Transduction
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%      
    Three samples of known concentration were tested twenty times on one plate to assess.  
    Inter-assay Precision (Precision between assays): CV%<10%      
    Three samples of known concentration were tested in twenty assays to assess.    
                 
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human THSD4 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　 Sample Serum(n=4)  
    1:20 Average % 88  
    Range % 81-95  
    1:40 Average % 91  
    Range % 86-97  
    1:80 Average % 97  
    Range % 91-102  
    1:160 Average % 102  
    Range % 97-107  
  • 回收率：
    The recovery of human THSD4 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range  
    Serum (n=5) 103 95-110  
    EDTA plasma (n=4) 93 85-98  
                 
                 
  • 標(biāo)準(zhǔn)曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/ml OD1 OD2 Average Corrected  
    800 2.675 2.870 2.773 2.674  
    400 2.324 2.345 2.335 2.236  
    200 1.618 1.655 1.637 1.538  
    100 0.864 0.901 0.883 0.784  
    50 0.502 0.496 0.499 0.400  
    25 0.324 0.345 0.335 0.236  
    12.5 0.198 0.200 0.199 0.100  
    0 0.101 0.096 0.099 　  
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能：
    Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN.
  • 基因功能參考文獻：
    1. In breast cancer, some GATA3 effects shift from tumor suppressing to tumor promoting during tumorigenesis, with deregulation of three genes, BCL2, DACH1, THSD4, representing major GATA3-controlled processes in cancer progression. PMID: 25410484
    2. ADAMTSL6beta has a role in fibrillin-1 microfibril formation PMID: 21880733
    3. THSD4 polymorphism was not found to be associated with COPD risk PMID: 21965014
    4. Variations may be important determinants of osteoporosis in Japanese women. PMID: 18488137
  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25835

    OMIM: 614476

    KEGG: hsa:79875

    STRING: 9606.ENSP00000261862

    UniGene: Hs.387057



主站蜘蛛池模板： 久久精品99国产国产精| a三级三级成人网站在线视频 | 国产激情з∠视频一区二区| 老司机午夜福利视频| 亚洲国产精品13p| 亚洲欧美成人一区二区在线| 亚洲欧美成aⅴ人在线观看| 少妇荡乳情欲办公室456视频| 国产亚洲精品久久久久小| 亚洲国产精品无码久久一区二区| 少妇裸体性生交| 欧洲熟妇色xxxxx欧美老妇伦| 午夜成人爽爽爽视频在线观看| 亚洲精品国产一二三无码av| 成在线人av免费无码高潮喷水 | 国产边摸边吃奶边做爽视频| 西西艺术人像摄影| 国产成人综合色就色综合| 美女内射毛片在线看免费人动物| 亚洲精品国产综合麻豆久久99| 校花高潮抽搐冒白浆| 各种少妇正面bbw撒尿 | 亚洲国产精品久久久久秋霞影院| 换脸国产av一区二区三区| 欧美人与动牲交免费观看网| 欧美一区二区三区| 香港三级日本三级a视频 | 国产高清在线精品一区| 亚洲国产成人极品综合| 国产sp调教打屁股视频网站| 国产xxxx99真实实拍| 中文字幕在线观看| 国产亚洲人成网站观看| 色综合久久久无码中文字幕波多 | 国产亚洲精品久久久久久彩霞| 人人妻人人澡人人爽欧美一区双 | 欧美激情一区二区成人| 亚洲综合久久成人a片| 蜜臀av在线播放| 日韩一区二区三区射精-百度| 国产牛仔裤网站精品|