在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Thiomorpholine-carboxylate dehydrogenase (CRYM)

Recombinant Human Thiomorpholine-carboxylate dehydrogenase (CRYM)

  • 中文名稱：
    Recombinant Human Thiomorpholine-carboxylate dehydrogenase(CRYM)
  • 貨號：
    CSB-YP622791HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Thiomorpholine-carboxylate dehydrogenase(CRYM)
  • 貨號：
    CSB-EP622791HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Thiomorpholine-carboxylate dehydrogenase(CRYM)
  • 貨號：
    CSB-EP622791HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Thiomorpholine-carboxylate dehydrogenase(CRYM)
  • 貨號：
    CSB-BP622791HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Thiomorpholine-carboxylate dehydrogenase(CRYM)
  • 貨號：
    CSB-MP622791HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CRYM
  • Uniprot No.：
  • 別名：
    CRYM; CRYM_HUMAN; Crystallin mu; DFNA 40; DFNA40; Ketimine reductase; Mu crystallin homolog; Mu-crystallin homolog; NADP regulated thyroid hormone binding protein; NADP-regulated thyroid-hormone-binding protein; OTTHUMP00000115878; THBP; Thiomorpholine carboxylate dehydrogenase
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-314
  • 氨基酸序列
    MSRVPAFLSA AEVEEHLRSS SLLIPPLETA LANFSSGPEG GVMQPVRTVV PVTKHRGYLG VMPAYSAAED ALTTKLVTFY EDRGITSVVP SHQATVLLFE PSNGTLLAVM DGNVITAKRT AAVSAIATKF LKPPSSEVLC ILGAGVQAYS HYEIFTEQFS FKEVRIWNRT KENAEKFADT VQGEVRVCSS VQEAVAGADV IITVTLATEP ILFGEWVKPG AHINAVGASR PDWRELDDEL MKEAVLYVDS QEAALKESGD VLLSGAEIFA ELGEVIKGVK PAHCEKTTVF KSLGMAVEDT VAAKLIYDSW SSGK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors.
  • 基因功能參考文獻：
    1. Results suggest that mu-crystallin may play roles in development of cortical and hippocampal pyramidal cells in the early postnatal period, and in the later period, performs cell-specific functions in selected neuronal populations. PMID: 29603402
    2. These findings confirm that, mechanistically, ketimine reductase/CRYM acts as a classical imine reductase and may explain the finding of bound pyruvate in the crystallized protein. PMID: 26173510
    3. ketimine reductase is a key enzyme in the pipecolate pathway, which is the main lysine degradation pathway in the brain PMID: 25931162
    4. The expression of mu-crystallin was regulated through the AP-1 site in the promoter. PMID: 23508717
    5. The purified human mu-crystallin was confirmed to have ketimine reductase activity with a maximum specific activity similar to that of native ovine ketimine reductase PMID: 21332720
    6. Its enzyme function has been determined as a ketimine reductase in mammalian brain. PMID: 21332720
    7. Its ketimine reductase activity is strongly inhibited by thyroid hormones. PMID: 21332720
    8. This protein has been found differentially expressed in thalami from patients with schizophrenia. PMID: 20471030
    9. This is the first report linking hyperglycemia with thyroid hormone binding protein CRYM and suggests that the role of CRYM in diabetic complications should be further investigated. PMID: 20018174
    10. Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues PMID: 12471561
    11. up-regulation of mu-crystallin may play a specific and important role in pathogenesis of facioscapulohumeral muscular dystrophy PMID: 17451686
    12. CRYM is a novel androgen-regulated gene whose expression is elevated in prostate cancer but down-regulated in castration therapy-resistant tumors. PMID: 19353593
    13. Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. PMID: 19165527
    14. This protein has been found differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. PMID: 19110265

    顯示更多

    收起更多

  • 相關疾病：
    Deafness, autosomal dominant, 40 (DFNA40)
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Ornithine cyclodeaminase/mu-crystallin family
  • 組織特異性：
    Expressed in neural tissue, muscle and kidney.
  • 數據庫鏈接：

    HGNC: 2418

    OMIM: 123740

    KEGG: hsa:1428

    STRING: 9606.ENSP00000219599

    UniGene: Hs.924



主站蜘蛛池模板： 成人看的污污超级黄网站免费| аⅴ资源中文在线天堂| 免费纯肉3d动漫无码网站| 青青青国产精品国产精品美女 | 精国产品一区二区三区a片| 特级欧美插插插插插bbbbb| 波多野结衣一区二区免费视频 | 四川丰满妇女毛片四川话| 强辱丰满人妻hd中文字幕| 在线观看国产日韩亚洲中| 在线播放午夜理论片| 三级4级全黄60分钟| 欲色影视天天一区二区三区色香欲| 久久精品成人免费观看97| 亚洲精品久久久久avwww潮水| 成人国产精品一区二区网站公司| 狠狠久久噜噜熟女| 爆乳高潮喷水无码正在播放| 国产真实伦在线观看| 一区二区国产精品精华液| 六月丁香综合在线视频| 97夜夜澡人人双人人人喊| 欧美性色19p| 成人视频在线观看| 邻居少妇张开腿让我爽了一夜| 亚洲人成人无码www影院| 中年熟妇的大黑p| 亚洲精品国产综合麻豆久久99| 真人啪啪高潮喷水呻吟无遮挡| 亚洲人成电影网站色www| 亚洲国产成人va在线观看天堂| 亚洲国产中文曰韩丝袜| 欧美熟妇色ⅹxxx欧美妇| 久久久精品国产sm最大网站| 国产精品内射视频免费| 久久精品国产免费播| 少妇久久久久久被弄到高潮| 国产成人 综合 亚洲欧洲| 久久99精品国产免费观观 | 国产午夜福利片| 大陆国产乱人伦|