在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CRYM Antibody

  • 中文名稱:
    CRYM兔多克隆抗體
  • 貨號:
    CSB-PA006027GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CRYM
  • 別名:
    CRYM antibody; CRYM_HUMAN antibody; Crystallin mu antibody; DFNA 40 antibody; DFNA40 antibody; Ketimine reductase antibody; Mu crystallin homolog antibody; Mu-crystallin homolog antibody; NADP regulated thyroid hormone binding protein antibody; NADP-regulated thyroid-hormone-binding protein antibody; OTTHUMP00000115878 antibody; THBP antibody; Thiomorpholine carboxylate dehydrogenase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human CRYM
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors.
  • 基因功能參考文獻:
    1. Results suggest that mu-crystallin may play roles in development of cortical and hippocampal pyramidal cells in the early postnatal period, and in the later period, performs cell-specific functions in selected neuronal populations. PMID: 29603402
    2. These findings confirm that, mechanistically, ketimine reductase/CRYM acts as a classical imine reductase and may explain the finding of bound pyruvate in the crystallized protein. PMID: 26173510
    3. ketimine reductase is a key enzyme in the pipecolate pathway, which is the main lysine degradation pathway in the brain PMID: 25931162
    4. The expression of mu-crystallin was regulated through the AP-1 site in the promoter. PMID: 23508717
    5. The purified human mu-crystallin was confirmed to have ketimine reductase activity with a maximum specific activity similar to that of native ovine ketimine reductase PMID: 21332720
    6. Its enzyme function has been determined as a ketimine reductase in mammalian brain. PMID: 21332720
    7. Its ketimine reductase activity is strongly inhibited by thyroid hormones. PMID: 21332720
    8. This protein has been found differentially expressed in thalami from patients with schizophrenia. PMID: 20471030
    9. This is the first report linking hyperglycemia with thyroid hormone binding protein CRYM and suggests that the role of CRYM in diabetic complications should be further investigated. PMID: 20018174
    10. Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues PMID: 12471561
    11. up-regulation of mu-crystallin may play a specific and important role in pathogenesis of facioscapulohumeral muscular dystrophy PMID: 17451686
    12. CRYM is a novel androgen-regulated gene whose expression is elevated in prostate cancer but down-regulated in castration therapy-resistant tumors. PMID: 19353593
    13. Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. PMID: 19165527
    14. This protein has been found differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. PMID: 19110265

    顯示更多

    收起更多

  • 相關疾病:
    Deafness, autosomal dominant, 40 (DFNA40)
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Ornithine cyclodeaminase/mu-crystallin family
  • 組織特異性:
    Expressed in neural tissue, muscle and kidney.
  • 數據庫鏈接:

    HGNC: 2418

    OMIM: 123740

    KEGG: hsa:1428

    STRING: 9606.ENSP00000219599

    UniGene: Hs.924



主站蜘蛛池模板: 800av凹凸视频在线观看| 欧美人与动人物姣配xxxx| 国产成人精品福利一区二区三区 | 日日碰日日摸夜夜爽无码| 亚洲成年轻人电影网站www| 夜夜高潮夜夜爽夜夜爱| 国产福利视频一区二区| 欧美老妇牲交videos| 无码国产激情在线观看| 欧美日韩亚洲国产综合乱| 国产香蕉97碰碰久久人人| 爆乳熟妇一区二区三区霸乳| 国产精品香港三级国产av| 免费的av网站在线观看国产精品| 国产精品门事件av| 亚洲国产精品久久精品| 香蕉久久久久久久av网站| 国产高清视频在线观看69| 在线观看无码av网址| 久久久久99精品成人片直播| 日日摸天天碰中文字幕你懂的| 亚州中文字幕无码中文字幕| 情侣激情18内射骚话国产| 一本大道伊人av久久乱码| 老熟女毛茸茸浓毛| 国产嘿嘿嘿视频在线观看| 精品美女国产互换人妻| 在线精品国产成人综合| 久久久免费精品re6| 小12萝裸体自慰出白浆| 狠狠色丁香久久综合婷婷| 髙清国产性猛交xxxand| 三上悠亚精品一区二区久久| 日本熟妇美熟bbw| 国产精品免费久久久久影院仙踪林| 99精品人妻无码专区在线视频区| 在线人人车操人人看视频| 久久久国产精品无码一区二区| 国产成人无码午夜视频在线观看| 久久精品这里热有精品| 亚拍精品一区二区三区探花|