在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Tescalcin (TESC)

  • 中文名稱:
    人TESC重組蛋白
  • 貨號(hào):
    CSB-YP023393HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TESC重組蛋白
  • 貨號(hào):
    CSB-EP023393HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TESC重組蛋白
  • 貨號(hào):
    CSB-BP023393HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TESC重組蛋白
  • 貨號(hào):
    CSB-MP023393HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TESC
  • Uniprot No.:
  • 別名:
    TESC; CHP3Calcineurin B homologous protein 3; Tescalcin; TSC
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    2-214
  • 氨基酸序列
    GAAHSASEE VRELEGKTGF SSDQIEQLHR RFKQLSGDQP TIRKENFNNV PDLELNPIRS KIVRAFFDNR NLRKGPSGLA DEINFEDFLT IMSYFRPIDT TMDEEQVELS RKEKLRFLFH MYDSDSDGRI TLEEYRNVVE ELLSGNPHIE KESARSIADG AMMEAASVCM GQMEPDQVYE GITFEDFLKI WQGIDIETKM HVRFLNMETM ALCH
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.
  • 基因功能參考文獻(xiàn):
    1. This study found that the genotype of TESC at the rs7294919 locus and MDD had a significant interactive effect on the hippocampal subfield volume. PMID: 28575645
    2. High Tescalcin expression is associated with colorectal cancer. PMID: 27485112
    3. CHP3 functions as a novel negative regulator of cardiomyocyte hypertrophy via inhibition of GSK3alpha/beta phosphorylation. PMID: 25935310
    4. This study demonstrated that highly significant effects of rs7294919 of tescalcin on hippocampal gray matter volumes. PMID: 24776739
    5. a binding partner and regulator of subunit 4 of the COP9 signalosome PMID: 24659803
    6. TESC is overexpressed in colorectal cancer PMID: 24811141
    7. Loss of both N-myristoylation and calcium binding of CHP3 decreases cell surface stability of NHE1. PMID: 22984264
    8. Tescalcin is one of the key gene products that is involved in switching differentiation program in some cell types. PMID: 20060826
    9. CHP3 binds directly to the proximal juxtamembrane C-terminal region (amino acids 505-571) of rat NHE1 in the same region that binds CHP1 and CHP2. PMID: 18321853

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus. Cytoplasm. Membrane; Lipid-anchor. Cell membrane. Cell projection, lamellipodium. Cell projection, ruffle membrane.
  • 蛋白家族:
    Calcineurin regulatory subunit family, CHP subfamily
  • 組織特異性:
    Expressed in mature megakaryocytes and polymorphonuclear granulocytes (at protein level). Abundantly expressed in heart. Also expressed at a lower level in adult testis and salivary gland, and in the placenta.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 26065

    OMIM: 611585

    KEGG: hsa:54997

    STRING: 9606.ENSP00000334785

    UniGene: Hs.525709



主站蜘蛛池模板: 毛片免费视频在线观看| 伊人精品一本久久综合| 2021国产精品香蕉在线观看| 免费一区二区无码东京热| 国产精品毛片无码| 乱子轮熟睡1区| 亚洲高清专区日韩精品| 男女吃奶做爰猛烈紧视频| 国产suv精品一区二区33| 少妇性饥渴无码a区免费| 日韩伦人妻无码| 亚洲中文有码字幕青青| 99久久er热在这里只有精品99| 国精产品一区一区三区| 国产乱人伦在线播放| 777奇米四色成人影视色区| 精品国产第一福利网站| 曰批免费视频播放免费| 国产爆乳无码一区二区麻豆 | 同性女女黄h片在线播放| 97在线观看播放| 欧美黑人巨大xxxxx| 日韩理论午夜无码| 欧美日韩亚洲国产综合乱| 北条麻妃在线一区二区| 国产麻豆放荡av剧情演绎| 在线播放人成视频观看| 久久天天躁狠狠躁夜夜2019| 色婷婷综合中文久久一本| 狠狠做深爱婷婷久久综合一区| 国产人成高清在线视频99最全资源| 韩国精品视频一区二区在线播放 | 国产激情久久久久影院老熟女| 老司机导航亚洲精品导航| av第一福利网站| 99国产精品久久久久久久日本竹 | 手机看片精品国产福利| 浪潮av激情高潮国产精品| 欧美成人一区二区三区在线视频| 老司机久久一区二区三区| 国产精品亚亚洲欧关中字幕|