Recombinant Human Target of Nesh-SH3 (ABI3BP), partial

中文名稱：

Recombinant Human Target of Nesh-SH3(ABI3BP) ,partial
貨號：

CSB-YP772035HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Target of Nesh-SH3(ABI3BP) ,partial
貨號：

CSB-EP772035HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Target of Nesh-SH3(ABI3BP) ,partial
貨號：

CSB-EP772035HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Target of Nesh-SH3(ABI3BP) ,partial
貨號：

CSB-BP772035HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Target of Nesh-SH3(ABI3BP) ,partial
貨號：

CSB-MP772035HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

ABI3BP
Uniprot No.：

Q7Z7G0
別名：

ABI gene family member 3 (NESH) binding protein; ABI gene family member 3 binding protein; ABI gene family member 3-binding protein; ABI3BP; FLJ41743; FLJ41754; Nesh binding protein; Nesh BP; Nesh-binding protein; NeshBP; Target of Nesh SH3; Target of Nesh-SH3; Tarsh; TARSH_HUMAN
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

基因功能參考文獻：
1. ABI3BP is a susceptibility gene for Kashin-Beck disease in the Chinese Han population. PMID: 24442417
2. Thus, TARSH presumably represents a trigger gene for evoking cellular senescence, which has also been suggested to be involved in the prevention of tumorigenesis. PMID: 15752759
3. expression of TARSH mRNA is remarkably downregulated in all lung cancer cell lines examined; also TARSH expression was significantly low in all of the tumor specimens when compared to the expression in corresponding non-neoplastic lung tissue specimens PMID: 16205947
4. The loss of ABI3BP expression could play a functional role in thyroid tumorigenesis. PMID: 18559958
5. These results suggest that TARSH plays an important role in proliferation of replicative senescence and may serve as a trigger of tumor development. PMID: 19338757
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相關(guān)疾病：

Defects in ABI3BP has been found in a patient with isolated coloboma, a defect of the eye characterized by the absence of ocular structures due to abnormal morphogenesis of the optic cup and stalk, and the fusion of the fetal fissure (optic fissure). Isolated colobomas may be associated with an abnormally small eye (microphthalmia) or small cornea.
亞細(xì)胞定位：

Secreted.
組織特異性：

Expressed in brain, heart, lung, liver, pancreas kidney and placenta.
數(shù)據(jù)庫鏈接：

HGNC: 17265

OMIM: 606279

KEGG: hsa:25890

STRING: 9606.ENSP00000284322

UniGene: Hs.477015