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  4. Recombinant Human THO complex subunit 7 homolog (THOC7)

Recombinant Human THO complex subunit 7 homolog (THOC7)

  • 中文名稱：
    人THOC7重組蛋白
  • 貨號：
    CSB-YP746911HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人THOC7重組蛋白
  • 貨號：
    CSB-EP746911HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人THOC7重組蛋白
  • 貨號：
    CSB-EP746911HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人THOC7重組蛋白
  • 貨號：
    CSB-BP746911HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人THOC7重組蛋白
  • 貨號：
    CSB-MP746911HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    THOC7
  • Uniprot No.：
  • 別名：
    FLJ23445; fSAP24; Functional spliceosome associated protein 24; Functional spliceosome-associated protein 24; hTREX30; Ngg1 interacting factor 3 like 1 binding protein 1; Ngg1 interacting factor 3 like protein 1 binding protein 1; Ngg1-interacting factor 3-like protein 1-binding protein 1; NIF3L1 binding protein 1; NIF3L1-binding protein 1; NIF3L1BP1; THO complex 7 homolog (Drosophila); THO complex 7 homolog; THO complex subunit 7 homolog; THOC 7; thoc7; THOC7_HUMAN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    2-204
  • 氨基酸序列
    GAVTDDEVI RKRLLIDGDG AGDDRRINLL VKSFIKWCNS GSQEEGYSQY QRMLSTLSQC EFSMGKTLLV YDMNLREMEN YEKIYKEIEC SIAGAHEKIA ECKKQILQAK RIRKNRQEYD ALAKVIQHHP DRHETLKELE ALGKELEHLS HIKESVEDKL ELRRKQFHVL LSTIHELQQT LENDEKLSEV EEAQEASMET DPKP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.; The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
  • 基因功能參考文獻：
    1. THOC7 (50-137, amino acid numbers) binds to the N-terminal portion (1-199) of FMIP directly. PMID: 19059247
  • 亞細胞定位：
    Cytoplasm. Nucleus. Nucleus speckle.
  • 蛋白家族：
    THOC7 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29874

    OMIM: 611965

    KEGG: hsa:80145

    STRING: 9606.ENSP00000295899

    UniGene: Hs.288151



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