在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Substance-K receptor (TACR2), partial

Recombinant Human Substance-K receptor (TACR2), partial

  • 中文名稱：
    人TACR2重組蛋白
  • 貨號：
    CSB-YP023069HU1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人TACR2重組蛋白
  • 貨號：
    CSB-EP023069HU1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人TACR2重組蛋白
  • 貨號：
    CSB-EP023069HU1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人TACR2重組蛋白
  • 貨號：
    CSB-BP023069HU1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人TACR2重組蛋白
  • 貨號：
    CSB-MP023069HU1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    TACR2; NK2R; NKNAR; TAC2R; Substance-K receptor; SKR; NK-2 receptor; NK-2R; Neurokinin A receptor; Tachykinin receptor 2
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.
  • 基因功能參考文獻：
    1. This study revealed for the first time an increase of Mast Cells -nerve association and NK2R expression on Mast Cells during Allergic Rhinitis as well as nerve fibres containing receptors for mass cells. PMID: 28030866
    2. Neuropeptide signaling through neurokinin-1 and neurokinin-2 receptors augments antigen presentation by human dendritic cells PMID: 26371842
    3. The occurrence of a profound alteration in NK receptor expression in RMDD is a novel finding that suggests NK-1R and NK-2R pathways as possible players in major depressive disorder. PMID: 23142211
    4. NK2R-dependent neuropeptide signaling regulates Ag-specific T cell responses via activation of DC function PMID: 22474018
    5. This study demonistrated that no association of Tachykinin receptor 2 (TACR2) polymorphisms with Alzheimer's disease. PMID: 19375820
    6. Tachykinin NK2 receptors mediate smooth muscle contraction in human corpus cavernosum and spongiosum. PMID: 11906947
    7. Identification of a tachykinin NK(2) receptor splice variant. PMID: 12427486
    8. protease-activated receptor 2 agonists induced a contraction of murine intestinal smooth muscle that was mediated by nerves and requires both neurokinin 1 and 2 receptors PMID: 12801882
    9. NK2 receptors are compartmentalized at the plasma membrane PMID: 15294896
    10. We propose that the N-terminus of NKA is exposed and accessible to the extracellular medium. Subsequent amino acids of the NKA peptide become progressively more buried residues up to approximately one-third of the transmembrane-spanning domain. PMID: 17402972
    11. Data indicate that presynaptic and postsynaptic neuroneuronal and neuromuscular regulatory processes mediated by tachykinins via NK2r may occur for modulating human colonic motility. PMID: 17503489
    12. Increased proportion of alveolar macrophages expressing neurokinin 2 receptor may be involved in the pathogenesis of COPD. PMID: 17532769
    13. all three subtypes of NKRs are expressed in native human airway smooth muscle cells & IP3 levels are the primary mediators of NKR-stimulated initial [Ca2+]i increases, whereas store-operated Ca2+ channels mediate sustained phase of the [Ca2+]i increase. PMID: 18203813
    14. NK2 receptors are involved in the neuroneuronal and neuromuscular processes regulating human colonic motility. PMID: 18219665
    15. polymorphisms leading to the Ile23Thr and Arg375His amino acid exchanges are highly prevalent in the human TACR2 gene, but do affect the potency of the endogenous agonist NKA or small molecule antagonists with respect to intracellular Ca(2+) signalling PMID: 18601911
    16. The prevalence of the TACR2 mRNA alpha isoform strongly suggests a major involvement of tachykinin NK(2) receptor in the regulation of human colonic functions. PMID: 18835556

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 數據庫鏈接：

    HGNC: 11527

    OMIM: 162321

    KEGG: hsa:6865

    STRING: 9606.ENSP00000362403

    UniGene: Hs.88372



主站蜘蛛池模板： 午夜福利电影| 成年轻人网站色直接看| 亚洲成av人片天堂网九九 | 中文字幕av一区二区三区人妻少妇 | 野花社区在线观看视频| 亚洲伊人色欲综合网| 日本又黄又潮娇喘视频| 无码ol丝袜高跟秘书在线观看 | 久久www免费人成_看片老司机| 久久成人a毛片免费观看网站| 激情内射人妻1区2区3区| 亚洲 综合 欧美在线视频| 伊人久久大香线蕉综合影院首页| 色欲综合一区二区三区| 人妻精油按摩bd高清中文字幕| 欧美亚洲综合成人专区| 国产乱子伦精品免费视频| 丰满多毛少妇做爰视频爽爽和| 国产成人精品亚洲日本在线观看| 国产成人av综合久久| 国产精自产拍在线看中文| 综合自拍亚洲综合图区高清| 无码人妻少妇伦在线电影| 国产95在线 | 欧美| 日本高清在线www3344| 2021国产精品午夜久久| 又爽又黄又无遮挡的视频| 亚洲国产精品无码久久一线| 人妻精品动漫h无码网站| 护士被强女千到高潮视频| 曰曰摸夜夜添夜夜添高潮出水| 国产高清在线精品一本大道| 日本黄漫动漫在线观看视频| 国产真实伦在线观看| 国产精品久久无码一区二区三区网| 欧美大片18禁aaa免费视频| 亚洲欧美中文日韩v在线97| 亚洲日韩欧美国产高清αv| 欧美 国产日韩 综合在线| 国产v片在线播放免费无遮挡| 九九精品无码专区免费|