在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TACR2 Antibody

  • 中文名稱:
    TACR2兔多克隆抗體
  • 貨號:
    CSB-PA125699
  • 規(guī)格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA125699(TACR2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA125699(TACR2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 12%SDS-PAGE, Lysate: 30 μg, Lane 1-2: K562 cells, hela cells, Primary antibody: CSB-PA125699(TACR2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    TACR2; NK2R; NKNAR; TAC2R; Substance-K receptor; SKR; NK-2 receptor; NK-2R; Neurokinin A receptor; Tachykinin receptor 2
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Synthetic peptide of Human TACR2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.
  • 基因功能參考文獻(xiàn):
    1. This study revealed for the first time an increase of Mast Cells -nerve association and NK2R expression on Mast Cells during Allergic Rhinitis as well as nerve fibres containing receptors for mass cells. PMID: 28030866
    2. Neuropeptide signaling through neurokinin-1 and neurokinin-2 receptors augments antigen presentation by human dendritic cells PMID: 26371842
    3. The occurrence of a profound alteration in NK receptor expression in RMDD is a novel finding that suggests NK-1R and NK-2R pathways as possible players in major depressive disorder. PMID: 23142211
    4. NK2R-dependent neuropeptide signaling regulates Ag-specific T cell responses via activation of DC function PMID: 22474018
    5. This study demonistrated that no association of Tachykinin receptor 2 (TACR2) polymorphisms with Alzheimer's disease. PMID: 19375820
    6. Tachykinin NK2 receptors mediate smooth muscle contraction in human corpus cavernosum and spongiosum. PMID: 11906947
    7. Identification of a tachykinin NK(2) receptor splice variant. PMID: 12427486
    8. protease-activated receptor 2 agonists induced a contraction of murine intestinal smooth muscle that was mediated by nerves and requires both neurokinin 1 and 2 receptors PMID: 12801882
    9. NK2 receptors are compartmentalized at the plasma membrane PMID: 15294896
    10. We propose that the N-terminus of NKA is exposed and accessible to the extracellular medium. Subsequent amino acids of the NKA peptide become progressively more buried residues up to approximately one-third of the transmembrane-spanning domain. PMID: 17402972
    11. Data indicate that presynaptic and postsynaptic neuroneuronal and neuromuscular regulatory processes mediated by tachykinins via NK2r may occur for modulating human colonic motility. PMID: 17503489
    12. Increased proportion of alveolar macrophages expressing neurokinin 2 receptor may be involved in the pathogenesis of COPD. PMID: 17532769
    13. all three subtypes of NKRs are expressed in native human airway smooth muscle cells & IP3 levels are the primary mediators of NKR-stimulated initial [Ca2+]i increases, whereas store-operated Ca2+ channels mediate sustained phase of the [Ca2+]i increase. PMID: 18203813
    14. NK2 receptors are involved in the neuroneuronal and neuromuscular processes regulating human colonic motility. PMID: 18219665
    15. polymorphisms leading to the Ile23Thr and Arg375His amino acid exchanges are highly prevalent in the human TACR2 gene, but do affect the potency of the endogenous agonist NKA or small molecule antagonists with respect to intracellular Ca(2+) signalling PMID: 18601911
    16. The prevalence of the TACR2 mRNA alpha isoform strongly suggests a major involvement of tachykinin NK(2) receptor in the regulation of human colonic functions. PMID: 18835556

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 11527

    OMIM: 162321

    KEGG: hsa:6865

    STRING: 9606.ENSP00000362403

    UniGene: Hs.88372



主站蜘蛛池模板: 天天躁日日躁aaaxxⅹ| 亚洲中文字幕无码av| 99久久精品国产成人综合| 亚洲高清有码中文字| 麻豆人妻无码性色av专区| 精品国产卡一卡2卡3卡| 免费国精产品wnw2544| 国产成人精品亚洲午夜麻豆| 成人无码www在线看免费| 亚洲欧洲成人a∨在线观看| 在线精品亚洲第一区焦香| 成人试看120秒体验区| 成人欧美一区二区三区1314| 国产成人一区二区精品视频| 自偷自拍亚洲综合精品麻豆| 精品女同一区二区| 欧美大屁股xxxxhd黑色| 国色精品卡一卡2卡3卡4卡在线| 波多野结衣超清无码专区| 国产欧美精品一区二区色综合| 三级4级全黄60分钟| 久久国产精品无码hdav| 日韩人妻无码免费视频一二区| 激情综合婷婷丁香五月蜜桃| 色婷婷综合久久久久中文| 日韩精品一区二区三区免费视频| 欧美国产日韩a在线观看| 色欲av蜜桃一区二区三| 亚洲乱码一区二区三区在线观看| 人人妻人人做人人爽| 久久综合少妇11p| 无码av无码天堂资源网影音先锋| 免费国精产品wnw2544| 伊人蕉久中文字幕无码专区| 人人狠狠久久亚洲综合88| av无码欧洲亚洲电影网| 波多野结衣av手机在线观看 | 欧美人与动性xxxxbbbb| 农村欧美丰满熟妇xxxx| 成 人 在 线 免费观看| 国产国拍亚洲精品av|