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  4. Recombinant Human Striated muscle preferentially expressed protein kinase (SPEG), partial

Recombinant Human Striated muscle preferentially expressed protein kinase (SPEG), partial

  • 中文名稱：
    人SPEG重組蛋白
  • 貨號：
    CSB-YP623013HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SPEG重組蛋白
  • 貨號：
    CSB-EP623013HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人SPEG重組蛋白
  • 貨號：
    CSB-EP623013HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SPEG重組蛋白
  • 貨號：
    CSB-BP623013HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SPEG重組蛋白
  • 貨號：
    CSB-MP623013HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SPEG
  • Uniprot No.：
  • 別名：
    PEG1; Aortic preferentially expressed gene 1; Aortic preferentially expressed protein 1; APEG 1; APEG-1; BPEG; KIAA1297; MGC12676; Nuclear protein marker for differentiated aortic smooth muscle and down regulated with vascular injury; OTTHUMP00000196351; OTTHUMP00000196352; OTTHUMP00000196353; speG; SPEG complex locus; SPEG_HUMAN; SPEGalpha; SPEGbeta; striated muscle preferentially expressed protein kinase; Striated muscle preferentially expressed protein kinase
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells.
  • 基因功能參考文獻：
    1. SPEG is present in cardiac muscle, where it plays a critical role; therefore, individuals with SPEG mutations additionally present with dilated cardiomyopathy. PMID: 25087613
    2. Genomic rearrangement on APEG1 in arteriosclerosis was studied. PMID: 15784173
    3. the RGD motif might play a role not only in the adhesion of Aortic Preferentially Expressed Protein-1 and extracellular proteins but also in intracellular protein-protein interactions PMID: 16354304
  • 相關疾病：
    Myopathy, centronuclear, 5 (CNM5)
  • 亞細胞定位：
    [Isoform 3]: Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family
  • 組織特異性：
    Isoform 1 is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 is predominantly expressed in the aorta. Isoform 3 appears to be expressed only in highly differentiated ASMC in normal vessel walls and down-regulated in dediffer
  • 數據庫鏈接：

    HGNC: 16901

    OMIM: 615950

    KEGG: hsa:10290

    STRING: 9606.ENSP00000311684

    UniGene: Hs.21639



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