在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Spermatogenesis-associated protein 13 (SPATA13)

Recombinant Human Spermatogenesis-associated protein 13 (SPATA13)

  • 中文名稱：
    人SPATA13重組蛋白
  • 貨號：
    CSB-YP842724HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SPATA13重組蛋白
  • 貨號：
    CSB-EP842724HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人SPATA13重組蛋白
  • 貨號：
    CSB-EP842724HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SPATA13重組蛋白
  • 貨號：
    CSB-BP842724HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SPATA13重組蛋白
  • 貨號：
    CSB-MP842724HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    APC-stimulated guanine nucleotide exchange factor 2; ARHGEF29; Asef2; FLJ31208; RP11-307N16.3; Spata13; Spermatogenesis-associated protein 13; SPT13_HUMAN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-652
  • 氨基酸序列
    MTSASPEDQN APVGCPKGAR RRRPISVIGG VSLYGTNQTE ELDNLLTQPA SRPPMPAHQV PPYKAVSARF RPFTFSQSTP IGLDRVGRRR QMRASNVSSD GGTEPSALVD DNGSEEDFSY EDLCQASPRY LQPGGEQLAI NELISDGNVV CAEALWDHVT MDDQELGFKA GDVIQVLEAS NKDWWWGRSE DKEAWFPASF VRLRVNQEEL SENSSSTPSE EQDEEASQSR HRHCENKQQM RTNVIREIMD TERVYIKHLR DICEGYIRQC RKHTGMFTVA QLATIFGNIE DIYKFQRKFL KDLEKQYNKE EPHLSEIGSC FLQNQEGFAI YSEYCNNHPG ACLELANLMK QGKYRHFFEA CRLLQQMIDI AIDGFLLTPV QKICKYPLQL AELLKYTTQE HGDYSNIKAA YEAMKNVACL INERKRKLES IDKIARWQVS IVGWEGLDIL DRSSELIHSG ELTKITKQGK SQQRTFFLFD HQLVSCKKDL LRRDMLYYKG RLDMDEMELV DLGDGRDKDC NLSVKNAFKL VSRTTDEVYL FCAKKQEDKA RWLQACADER RRVQEDKEMG MEISENQKKL AMLNAQKAGH GKSKGYNRCP VAPPHQGLHP IHQRHITMPT SVPQQQVFGL AEPKRKSSLF WHTFNRLTPF RK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
  • 基因功能參考文獻：
    1. Phosphorylation of S106 modulates Asef2 guanine nucleotide exchange factor activity and Asef2-mediated cell migration and adhesion turnover. PMID: 24874604
    2. A new role for Rac activation, promoted by Asef2, in modulating actomyosin contractility. PMID: 24144700
    3. Asef2 activates Rac1 to modulate adhesion and actin dynamics and thereby regulate cell migration. PMID: 19934221
    4. These results suggest that similar to Asef, Asef2 plays an important role in cell migration, and that Asef2 activated by truncated mutant APC is required for aberrant migration of colorectal tumor cells. PMID: 17599059
    5. Asef2, Neurabin2 and APC cooperatively regulate actin cytoskeletal organization and are required for HGF-induced cell migration. PMID: 19151759
    6. Observational study of gene-disease association. (HuGE Navigator) PMID: 19910543

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell projection, filopodium. Cell projection, lamellipodium. Cell projection, ruffle membrane. Note=Accumulates in the lamellipodium and ruffle membrane in response to hepatocyte growth factor (HGF) treatment.
  • 組織特異性：
    Expressed at high levels in the placenta, spleen and kidney, at moderate levels in lung, small intestine, liver, brain and heart, and at low levels in skeletal muscle. Expression is aberrantly enhanced in most colorectal tumors.
  • 數據庫鏈接：

    HGNC: 23222

    OMIM: 613324

    KEGG: hsa:221178

    STRING: 9606.ENSP00000371542

    UniGene: Hs.434298



主站蜘蛛池模板： 国产人澡人澡澡澡人碰视频| 久久婷婷是五月综合色| 国产欧美亚洲日韩图片| 亚洲精品毛片一区二区三区| 中文字幕精品亚洲无线码一区| 午夜天堂精品久久久久| 免费国产a国产片高清| 人妻少妇乱子伦无码专区| 欧美成aⅴ人高清免费| 18禁止观看强奷免费国产大片| 国产在线乱子伦一区二区| 国产精品高清网站| 国产精品va无码一区二区| 亚洲精品一区二区三区蜜臀| yyyy11111少妇无码影院| 久久超碰97人人做人人爱| 亚洲熟妇丰满大屁股熟妇图片| 日本乱妇乱子视频| 男人添女人囗交做爰视频| 国产肥白大熟妇bbbb视频| 福利视频在线播放| 日韩精品一区二区av在线观看| 国产超碰人人模人人爽人人喊| 免费午夜福利不卡片在线 | 熟女人妻少妇精品视频| 日韩a片无码一区二区三区电影| 亚洲综合欧美在线一区在线播放| 天堂资源中文| av免费不卡国产观看| 免费大黄网站| 秋霞电影网午夜鲁丝片无码| 狠狠噜狠狠狠狠丁香五月| 狠狠色丁香久久综合婷婷| 免费国偷自产拍精品视频 | 欧美老妇与zozozo交| 99在线精品视频在线观看| 看国产一毛片在线看手机看| 亚洲免费视频免在线观看| 人妻av中文字幕久久| 免费大黄网站在线观| 日韩 国产 变态另类 欧美|