在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Solute carrier family 22 member 18 (SLC22A18), partial

Recombinant Human Solute carrier family 22 member 18 (SLC22A18), partial

  • 中文名稱：
    人SLC22A18重組蛋白
  • 貨號(hào)：
    CSB-YP822182HU
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    人SLC22A18重組蛋白
  • 貨號(hào)：
    CSB-EP822182HU
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    人SLC22A18重組蛋白
  • 貨號(hào)：
    CSB-EP822182HU-B
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SLC22A18重組蛋白
  • 貨號(hào)：
    CSB-BP822182HU
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SLC22A18重組蛋白
  • 貨號(hào)：
    CSB-MP822182HU
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SLC22A18
  • Uniprot No.：
  • 別名：
    SLC22A18; BWR1A; BWSCR1A; HET; IMPT1; ITM; ORCTL2; SLC22A1L; TSSC5; Solute carrier family 22 member 18; Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein; Efflux transporter-like protein; Imprinted multi-membrane-spanning polyspecific transporter-related protein 1; Organic cation transporter-like protein 2; ORCTL-2; Solute carrier family 22 member 1-like; Tumor-suppressing STF cDNA 5 protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein; p45-Beckwith-Wiedemann region 1 A; p45-BWR1A
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney.
  • 基因功能參考文獻(xiàn)：
    1. Data provide evidence that SLC22A18 and/or CDKN1C are tumor modifier genes involved in the tumorigenesis of SDHD-mutated paraganglioma. PMID: 27402879
    2. Establish SLC22A18 as a tumor suppressor in colon epithelial cells and propose that SLC22A18 is potentially a marker of diagnostic and prognostic values. PMID: 26196590
    3. microRNA-137 functions as a tumor suppressor in human non-small cell lung cancer by targeting SLC22A18 PMID: 25498886
    4. Upregulated expression of SLC22A18 enhanced the radiosensitivity of glioma U251 cells. PMID: 24481489
    5. SLC22A18 protein expression predicted a significantly shorter overall survival in 51 patients receiving TMZ therapy, whereas no differences in overall survival were observed in 35 patients without TMZ therapy PMID: 23514245
    6. SLC22A18 functions as a tumor suppressor in glioma and represents a candidate biomarker for long-term survival in this disease. PMID: 22153794
    7. The expression level of SLC22A18 in non-small cell lung cancer was significantly higher than that in normal tissue. PMID: 22237119
    8. SLC22A18 downregulation via promoter methylation is associated with the development and progression of glioma. PMID: 21936894
    9. Low expression of SLC22A18 was associated with tumor progression, recurrence and poor survival after breast surgery PMID: 21144813
    10. SLC22A18 gene is imprinted, with preferential expression from the maternal allele. PMID: 9751628
    11. involved in the drug resistance mechanism of tumors PMID: 11925925
    12. UbcH6-RING105 may define a novel ubiquitin-proteasome pathway that targets TSSC5 in mammalian cells PMID: 16314844
    13. study reports the imprinting status of SLC22A18AS in breast tissue and breast cancer, and shows that gain of imprinting affects both the sense, and antisense transcripts at this locus PMID: 16624517
    14. Mutational analysis of the two Sp1 sites suggested their requirement for the promoter activityof SLC22A18. PMID: 18996451
    15. recent demonstration that the promoter of this gene is positively regulated by Sp1 PMID: 18996451

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Lung cancer (LNCR); Rhabdomyosarcoma, embryonal, 1 (RMSE1)
  • 亞細(xì)胞定位：
    Apical cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family
  • 組織特異性：
    Expressed at high levels in adult and fetal kidney and liver, and adult colon. Expressed in fetal renal proximal tubules (at protein level). Expressed at lower levels in heart, brain and lung.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 10964

    OMIM: 114480

    KEGG: hsa:5002

    STRING: 9606.ENSP00000307859

    UniGene: Hs.50868



主站蜘蛛池模板： 99久久国产综合精品麻豆| 亚洲伊人久久精品酒店| 欧美黑人巨大videos精品| 少妇人妻邻居| 天天做天天大爽天天爱| 亚洲丁香五月激情综合| 正在播放国产乱子伦最新视频| 成人aaa片一区国产精品| 欧美激情一区二区三区| 国产原创av中文在线观看| 午夜男女刺激爽爽影院| 无码精品人妻一区二区三区漫画 | 亚洲一区二区无码偷拍| 国产精品白丝喷浆| 国产女人高潮毛片| 国产欧美熟妇另类久久久| 中文字幕在线亚洲二区| 中文字幕人妻偷伦在线视频| 亚洲日韩一区二区三区| 成 人 在 线 免费观看| 国产午夜福利在线播放87| 久久久免费无码成人影片| 国产999精品久久久久久| 国产精品激情欧美可乐视频| 亚洲午夜久久久无码精品网红a片| 久久久亚洲欧洲日产国码aⅴ| 欧美日韩国产免费一区二区三区| 人妻少妇伦在线麻豆m电影| 亚洲美女被黑人巨大在线播放| 少妇人妻邻居| 在线看片无码永久免费视频| 亚洲一本一道一区二区三区| 黑人巨大精品欧美| 国产精成人品| 夜夜高潮夜夜爽高清视频| 婷婷色香五月综合激激情| 无码任你躁久久久久久老妇| 精品国产福利久久久| 中文字幕无码免费久久99| 特黄特色的大片观看免费视频| 国产成人av国语在线观看|