在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Solute carrier family 12 member 7 (SLC12A7 KCC4)

  • 中文名稱:
  • 貨號:
    CSB-YP893907HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-EP893907HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-EP893907HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-BP893907HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-MP893907HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    S12A7
  • Uniprot No.:
  • 別名:
    Solute carrier family 12 member 7; Electroneutral potassium-chloride cotransporter 4; K-Cl cotransporter 4; SLC12A7 KCC4
  • 種屬:
    Homo sapiens (Human)
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification.
  • 基因功能參考文獻:
    1. SLC12A7 gene amplification and overexpression occurs frequently in adrenocortical carcinoma and may play a role in adrenocortical carcinoma tumorigenesis. PMID: 26454676
    2. Negative stain transmission electron microscopy and single particle analysis of KCC4 and the aquaporin-1 AQP1 water channel, revealed the expected quaternary structures within homogeneous preparations, and thus correct protein folding and assembly. PMID: 21760919
    3. analysis of differences in large extracellular loop between the K(+)-Cl(-) cotransporters KCC2 and KCC4 PMID: 20516068
    4. KCC4 and H+,K+-ATPase are the main machineries for basal HCl secretion in the apical canalicular membrane of the resting parietal cell. They also may contribute in part to massive acid secretion in the stimulated state. PMID: 18984587
    5. In the metastatic cancer tissues, KCC4 colocalizes with IGF-I or EGF. PMID: 19887603
    6. Mice lacking SLC12A7 function suffer from deafness and renal metabolic acidosis. The phenotype suggests a function in inner ear potassium recycling. A function in the proton secreting alpha-intercalating cells of the kidney is shown. PMID: 11976689

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    SLC12A transporter family
  • 組織特異性:
    Detected in muscle, brain, lung, heart and kidney.
  • 數據庫鏈接:

    HGNC: 10915

    OMIM: 604879

    KEGG: hsa:10723

    STRING: 9606.ENSP00000264930

    UniGene: Hs.172613



主站蜘蛛池模板: 日韩精品一区二区三区| 免费无码av片在线观看国产| 久久伊99综合婷婷久久伊| 无码人妻天天拍夜夜爽| 国产成人国产在线观看| 中文有码无码人妻在线| 暖暖视频日本在线观看| 国产大屁股视频免费区| 国产破外女出血视频| 亚洲妇女自偷自偷图片| 欧美亚洲精品一区二区| 中文乱码字慕人妻熟女人妻| 国产好爽…又高潮了毛片| 亚洲 欧美 自拍 美腿 卡通| 三级网站视频在在线播放| 国产免费无码一区二区三区| 中文在线а√在线| 黑人狠狠的挺身进入| 亚洲精品乱码久久久久久日本麻豆| 色婷婷av一区二区三区浪潮| 97精品国产97久久久久久免费| 欧美日韩一区二区三区视频播放 | 少妇的肉体在线观看| 99re6在线视频精品免费| 久久国产美女精品久久| 精品熟女少妇av久久免费软件| 一本一本久久a久久精品综合麻豆| 精品无码无人网站免费视频| 法国啄木乌av片在线播放| 国产av亚洲精品ai换脸电影| 中文字幕无线码成人免费看| 国产95在线 | 亚洲| 少妇又紧又色又爽又刺激视频| 国产情侣大量精品视频| 黑色丝袜无码中中文字幕| 成年美女黄网站色大片免费看| 日韩人妻无码一区二区三区99| 色欲天天天综合网| 日产精品久久久久久久蜜臀| 欧洲亚洲精品久久久久| 人人妻人人澡人人爽国产|