在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Sodium/potassium-transporting ATPase subunit gamma (FXYD2)

  • 中文名稱:
    人FXYD2重組蛋白
  • 貨號(hào):
    CSB-EP009090HU
  • 規(guī)格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    FXYD2; ATP1C; ATP1G1; Sodium/potassium-transporting ATPase subunit gamma; Na(+)/K(+) ATPase subunit gamma; FXYD domain-containing ion transport regulator 2; Sodium pump gamma chain
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Full Length of Isoform 2
  • 來(lái)源:
    E.coli
  • 分子量:
    34.4kDa
  • 表達(dá)區(qū)域:
    1-64aa
  • 氨基酸序列
    MDRWYLGGSPKGDVDPFYYDYETVRNGGLIFAGLAFIVGLLILLSRRFRCGGNKKRRQINEDEP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal GST-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
  • 基因功能參考文獻(xiàn):
    1. FXYD2 is functionally upregulated in ovarian clear cell carcinoma and may serve as a promising prognostic biomarker and therapeutic target of cardiac glycosides in OCCC PMID: 26910837
    2. Recurrent FXYD2 p.Gly41Arg mutation is associated with isolated dominant hypomagnesaemia. PMID: 25765846
    3. FXYD2b could regulate the Na,K-ATPase by modulating the effective membrane surface electrostatics near the ion binding sites of the pump. PMID: 24794573
    4. our findings suggested that FXYD2c played a role in regulation of NKA activity by enhancing the expression of NKA in HK-2 cells upon hypertonic challenge. PMID: 24258619
    5. PCBD1 (dimerization cofactor of HNF-1alpha) is coactivator of the HNF1B-mediated transcription necessary for fine tuning ATPase Na+/K+ transporting gamma 1 polypeptide (FXYD2) transcription in the distal convoluted tubule. PMID: 24204001
    6. This is the first report demonstrating the potential utility of FXYD2 immunohistochemistry in the diagnosis of chromophobe renal cell carcinoma PMID: 23196795
    7. findings confirm the presence of an FXYD2 peptide in the crab gill Na,K-ATPase and demonstrate that this peptide plays an important role in regulating enzyme activity PMID: 22588134
    8. wild type HNF1B specifically induces FXYD2A transcription whereas all HNF1B mutants partially prevented it. PMID: 21130072
    9. Datab propose human FXYD2gammaa as a novel beta cell-specific biomarker. PMID: 20379810
    10. Study reveals, in various human tissues, the specific expression of FXYD2, which may associate with Na, K-ATPase in selected cell types and modulate its catalytic properties. PMID: 19879113
    11. the TM domain of FYXD2 effects the shift in apparent Na+ affinity PMID: 12907667
    12. Activity of GLAST directs FXYD2 protein/gamma subunit to the cell surface, that leads to the activation of the astroglial sodium pump. PMID: 17316900
    13. structures of the FXYD proteins (with emphasis on 1-4), as well as their dynamics and their associations with the lipid PMID: 18000745
    14. results suggest that FXYD2 can mediate basolateral extrusion of magnesium from cultured renal epithelial cells and provide new insights into the understanding of the possible physiological roles of FXYD2 wild-type and mutant proteins. PMID: 18448590
    15. Expression in transfectants reduces Na+ and K+ affinity of Na,K-ATPase. Endogenous expression in certain nephron segments correlates with low Na+ affinity in Na,K-ATPase. PMID: 10559186

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Hypomagnesemia 2 (HOMG2)
  • 亞細(xì)胞定位:
    Membrane; Single-pass type III membrane protein.
  • 蛋白家族:
    FXYD family
  • 組織特異性:
    Expressed in the distal convoluted tubule in the kidney. Found on basolateral membranes of nephron epithelial cells.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 4026

    OMIM: 154020

    KEGG: hsa:486

    STRING: 9606.ENSP00000292079

    UniGene: Hs.731865



主站蜘蛛池模板: 亚洲精品av一区午夜福利| 777天堂麻豆爱综合视频| 久久久精品人妻无码专区不卡| 亚洲人成亚洲人成在线观看| 推油少妇久久99久久99久久| 玩弄人妻少妇500系列视频| 亚洲中文字幕av不卡无码| 亚洲 综合 校园 欧美 制服 | 成人夜色视频网站在线观看| 污污污污污污污网站污| 国产成人精品日本亚洲网站| 夜夜影院未满十八勿进| 久99久无码精品视频免费播放| 国产精品国语对白露脸在线播放 | 伊人情人色综合网站| 亚洲欧美综合国产精品二区| 精品熟女少妇av久久免费软件| 久久久国产精品黄毛片| 女人下边被添全过视频| 国产99在线 | 亚洲| 国产成人乱色伦区| 日产a一a区二区www| 亚欧色一区w666天堂| 97久久香蕉国产线看观看| 亚洲久热中文字幕在线| 337p日本大胆欧美裸体艺术| 中文字幕亚洲码在线观看| 欧美乱人伦人妻中文字幕| 久久无码国产专区精品| 国产在线无码播放不卡视频| 国产成人一区二区青青草原| 精品久久久无码人妻中文字幕| 亚洲欧美精品suv| 在线va无卡无码高清| 免费毛儿一区二区十八岁| 精品国产美女福到在线不卡| 欧美性黑人极品hd另类| 免费做a爰片久久毛片a片下载| 九九综合va免费看| 亚洲精品一区二区三区不卡| 亚洲自偷自偷在线成人网址|