在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Sodium/potassium-transporting ATPase subunit gamma (FXYD2), partial

  • 中文名稱:
    人FXYD2重組蛋白
  • 貨號:
    CSB-YP009090HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人FXYD2重組蛋白
  • 貨號:
    CSB-EP009090HU1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人FXYD2重組蛋白
  • 貨號:
    CSB-EP009090HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人FXYD2重組蛋白
  • 貨號:
    CSB-BP009090HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人FXYD2重組蛋白
  • 貨號:
    CSB-MP009090HU1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    FXYD2; ATP1C; ATP1G1; Sodium/potassium-transporting ATPase subunit gamma; Na(+)/K(+) ATPase subunit gamma; FXYD domain-containing ion transport regulator 2; Sodium pump gamma chain
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 表達區域:
    1-64
  • 氨基酸序列
    MDRWYLGGSPKGDVDPFYYDYETVRNGGLIFAGLAFIVGLLILLSRRFRCGGNKKRRQINEDEP
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
  • 基因功能參考文獻:
    1. FXYD2 is functionally upregulated in ovarian clear cell carcinoma and may serve as a promising prognostic biomarker and therapeutic target of cardiac glycosides in OCCC PMID: 26910837
    2. Recurrent FXYD2 p.Gly41Arg mutation is associated with isolated dominant hypomagnesaemia. PMID: 25765846
    3. FXYD2b could regulate the Na,K-ATPase by modulating the effective membrane surface electrostatics near the ion binding sites of the pump. PMID: 24794573
    4. our findings suggested that FXYD2c played a role in regulation of NKA activity by enhancing the expression of NKA in HK-2 cells upon hypertonic challenge. PMID: 24258619
    5. PCBD1 (dimerization cofactor of HNF-1alpha) is coactivator of the HNF1B-mediated transcription necessary for fine tuning ATPase Na+/K+ transporting gamma 1 polypeptide (FXYD2) transcription in the distal convoluted tubule. PMID: 24204001
    6. This is the first report demonstrating the potential utility of FXYD2 immunohistochemistry in the diagnosis of chromophobe renal cell carcinoma PMID: 23196795
    7. findings confirm the presence of an FXYD2 peptide in the crab gill Na,K-ATPase and demonstrate that this peptide plays an important role in regulating enzyme activity PMID: 22588134
    8. wild type HNF1B specifically induces FXYD2A transcription whereas all HNF1B mutants partially prevented it. PMID: 21130072
    9. Datab propose human FXYD2gammaa as a novel beta cell-specific biomarker. PMID: 20379810
    10. Study reveals, in various human tissues, the specific expression of FXYD2, which may associate with Na, K-ATPase in selected cell types and modulate its catalytic properties. PMID: 19879113
    11. the TM domain of FYXD2 effects the shift in apparent Na+ affinity PMID: 12907667
    12. Activity of GLAST directs FXYD2 protein/gamma subunit to the cell surface, that leads to the activation of the astroglial sodium pump. PMID: 17316900
    13. structures of the FXYD proteins (with emphasis on 1-4), as well as their dynamics and their associations with the lipid PMID: 18000745
    14. results suggest that FXYD2 can mediate basolateral extrusion of magnesium from cultured renal epithelial cells and provide new insights into the understanding of the possible physiological roles of FXYD2 wild-type and mutant proteins. PMID: 18448590
    15. Expression in transfectants reduces Na+ and K+ affinity of Na,K-ATPase. Endogenous expression in certain nephron segments correlates with low Na+ affinity in Na,K-ATPase. PMID: 10559186

    顯示更多

    收起更多

  • 相關疾病:
    Hypomagnesemia 2 (HOMG2)
  • 亞細胞定位:
    Membrane; Single-pass type III membrane protein.
  • 蛋白家族:
    FXYD family
  • 組織特異性:
    Expressed in the distal convoluted tubule in the kidney. Found on basolateral membranes of nephron epithelial cells.
  • 數據庫鏈接:

    HGNC: 4026

    OMIM: 154020

    KEGG: hsa:486

    STRING: 9606.ENSP00000292079

    UniGene: Hs.731865



主站蜘蛛池模板: 亚洲国产午夜精品理论片在线播放| 无码人妻丰满熟妇a片护士| 狠狠色狠狠色综合| 欧美疯狂性受xxxxx喷水| 中文字幕乱码一区二区三区免费| 香港曰本韩国三级网站| 一本加勒比hezyo无码专区| 野外做受又硬又粗又大视频| 人人玩人人添人人澡超碰偷拍| 日本少妇无码精品12p| 最新国产精品无码| 色 综合 欧美 亚洲 国产| 国产精品亚洲欧美大片在线看| 久久精品国产99久久丝袜蜜桃| 97超碰中文字幕久久精品| 久久国产精品无码网站| 国产精品沙发午睡系列990531| 亚洲中文字幕aⅴ无码天堂| 国产精品乱码久久久久软件| 欧洲熟妇色xxxx欧美老妇多毛 | 色综合久久久久久久久五月| 国产精品免费久久久久影院| 亚欧欧美人成视频在线| 国产乱人伦av在线a最新| 国产普通话对白刺激| 香蕉久久一区二区三区啪啪| 中文字幕人妻av一区二区| 无码少妇一区二区三区视频| 亚洲中文字幕无码爆乳| 欧美交a欧美精品喷水| 国产在线高清视频无码| 日韩精品一区二区午夜成人版| 久久久久有精品国产麻豆| 亚洲中文字幕无码av正片| 粗大黑人巨精大战欧美成人| 久久中文字幕人妻熟av女| 欧美三级不卡在线播放| 国产精品va在线观看h| 亚洲色大成网站www永久| 欧美高清精品一区二区| 乱子伦国产对白在线播放|