在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Sodium/potassium/calcium exchanger 6 (SLC24A6), partial

  • 中文名稱:
    人SLC8B1重組蛋白
  • 貨號:
    CSB-YP750360HU
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SLC8B1重組蛋白
  • 貨號:
    CSB-EP750360HU
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SLC8B1重組蛋白
  • 貨號:
    CSB-EP750360HU-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SLC8B1重組蛋白
  • 貨號:
    CSB-BP750360HU
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SLC8B1重組蛋白
  • 貨號:
    CSB-MP750360HU
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SLC8B1
  • Uniprot No.:
  • 別名:
    FLJ22233 ; Na(+)/K(+)/Ca(2+) exchange protein 6; Na(+)/K(+)/Ca(2+)-exchange protein 6; NCKX6; NCKX6_HUMAN; NCLX ; Slc24a6; Sodium/potassium/calcium exchanger ; Sodium/potassium/calcium exchanger 6; Solute carrier family 24 (sodium/potassium/calcium exchanger) member 6 ; Solute carrier family 24 member 6
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, by mediating the exchange of 3 sodium ions per 1 calcium ion. Plays a central role in mitochondrial calcium homeostasis by mediating mitochondrial calcium extrusion: calcium efflux is essential for mitochondrial function and cell survival, notably in cardiomyocytes. Regulates rates of glucose-dependent insulin secretion in pancreatic beta-cells during the first phase of insulin secretion: acts by mediating efflux of calcium from mitochondrion, thereby affecting cytoplasmic calcium responses. Required for store-operated Ca(2+) entry (SOCE) and Ca(2+) release-activated Ca(2+) (CRAC) channel regulation: sodium transport by SLC8B1 leads to promote calcium-shuttling that modulates mitochondrial redox status, thereby regulating SOCE activity. Involved in B-lymphocyte chemotaxis. Able to transport Ca(2+) in exchange of either Li(+) or Na(+), explaining how Li(+) catalyzes Ca(2+) exchange. In contrast to other members of the family its function is independent of K(+).
  • 基因功能參考文獻:
    1. It has been shown that the propagation of the TRPV1-induced cytosolic calcium and sodium fluxes into mitochondria is dependent on coordinated activity of NCLX and MCU. PMID: 27627464
    2. Store-operated Ca(2+) entry activates a mitochondrial redox transient which is dependent on NCLX and is required for preventing Orai1 inactivation through oxidation of a critical cysteine (Cys195) in the third transmembrane helix of Orai1. PMID: 28219928
    3. NCLX, but not LETM1, mediates Ca(2+) extrusion from mitochondria. By controlling the duration of matrix Ca(2+) elevations, NCLX contributes to the regulation of NAD(P)H production and to the conversion of Ca(2+) signals into redox changes. PMID: 24898248
    4. NCKX6 is a novel member of the Na+/Ca2+ exchanger superfamily PMID: 14625281
    5. NCLX catalyzes active Li(+)/Ca(2+) exchange. PMID: 15060069

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family, SLC24A subfamily
  • 組織特異性:
    Present in pancreatic beta-cells (at protein level).
  • 數據庫鏈接:

    HGNC: 26175

    OMIM: 609841

    KEGG: hsa:80024

    STRING: 9606.ENSP00000202831

    UniGene: Hs.286194



主站蜘蛛池模板: 51精品国产人成在线观看| 国产一卡二卡四卡无卡免费| 亚洲性猛交xxxx| 日韩国产成人精品视频| 成人精品一区二区三区电影免费| 在线看片免费人成视频影院看| 国产在线视频一区二区三区98| 人妻少妇精品久久久久久| 国产午夜精品av一区二区| 日躁夜躁狠狠躁2001| 小12萝裸体自慰出白浆| 男男又爽又黄又无遮挡网站| 久久精品aⅴ无码中文字字幕重口| 国产av人人夜夜澡人人爽 | 国产9 9在线 | 中文| 国内久久婷婷五月综合色| 久天啪天天久久99久孕妇| 搡老女人老妇女老熟妇| 国产精品国色综合久久| 国精品午夜福利视频| 亚洲国产中文在线视频| 在线永久免费观看黄网站| 天天澡天天揉揉av在线| 天天摸天天做天天添欧美| 久久成人国产精品| 亚洲国产精品国自产拍av| 51被公侵犯玩弄漂亮人妻| 精品国产一区二区三区av色诱| 撕开奶罩揉吮奶头视频| 少妇高潮喷潮久久久影院| 日韩综合亚洲色在线影院| 四虎www成人影院观看| 色综合中文综合网| 国产白嫩漂亮美女在线观看 | 伊人精品成人久久综合97| 51久久国产露脸精品国产| 欧美 日韩 亚洲 在线| 永久久久免费人妻精品| 日本免费一区二区三区| 国产9 9在线 | 中文| 国产在线欧美日韩精品一区|