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  4. Recombinant Human Serine/threonine-protein phosphatase 6 regulatory subunit 3 (PPP6R3), partial

Recombinant Human Serine/threonine-protein phosphatase 6 regulatory subunit 3 (PPP6R3), partial

  • 中文名稱：
    人PPP6R3重組蛋白
  • 貨號：
    CSB-YP686014HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PPP6R3重組蛋白
  • 貨號：
    CSB-EP686014HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PPP6R3重組蛋白
  • 貨號：
    CSB-EP686014HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PPP6R3重組蛋白
  • 貨號：
    CSB-BP686014HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PPP6R3重組蛋白
  • 貨號：
    CSB-MP686014HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PPP6R3
  • Uniprot No.：
  • 別名：
    C11orf23 ; Chromosome 11 open reading frame 23 ; KIAA1558; PP6R3 ; PP6R3_HUMAN; PPP6R3; Protein phosphatase 6 regulatory subunit 3 ; SAP190 ; SAPL ; SAPLa; SAPS domain family member 3; SAPS domain family; member 3; Serine/threonine-protein phosphatase 6 regulatory subunit 3; Sporulation induced transcript 4 associated protein SAPL; Sporulation-induced transcript 4-associated protein SAPL
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. May have an important role in maintaining immune self-tolerance.
  • 基因功能參考文獻：
    1. Results from a study on gene expression variability markers in early-stage human embryos shows that PPP6R3 is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
    2. we found a DPP9-PPP6R3 fusion transcript in one tumor showing a matching genomic 11;19-translocation. Another tumor had a rearrangement of DPP9 with PLIN3. Both rearrangements were associated with diminished expression of the 3' end of DPP9 corresponding to the breakpoints identified by RNA-seq. PMID: 28893231
    3. Molecular analyses revealed the presence and amplification of the novel PPPR6-USP6 gene fusion, which resulted in USP6 mRNA transcriptional upregulation. These findings further support the oncogenic role of the USP6 protease in mesenchymal neoplasia and expand the biologic potential of Nodular fasciitis PMID: 27113271
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    SAPS family
  • 組織特異性：
    Expressed in skeletal muscle, placenta, heart, pancreas, testis, brain, lung, liver, kidney, spleen, thymus, prostate, small intestine, colon and leukocytes.
  • 數據庫鏈接：

    HGNC: 1173

    OMIM: 610879

    KEGG: hsa:55291

    STRING: 9606.ENSP00000377390

    UniGene: Hs.503022



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