在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Serine/arginine-rich splicing factor 7 (SRSF7)

Recombinant Human Serine/arginine-rich splicing factor 7 (SRSF7)

  • 中文名稱：
    人SRSF7重組蛋白
  • 貨號：
    CSB-YP618089HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SRSF7重組蛋白
  • 貨號：
    CSB-EP618089HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人SRSF7重組蛋白
  • 貨號：
    CSB-EP618089HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SRSF7重組蛋白
  • 貨號：
    CSB-BP618089HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SRSF7重組蛋白
  • 貨號：
    CSB-MP618089HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SRSF7
  • Uniprot No.：
  • 別名：
    9G8; AAG3; arginine/serine-rich 7; HSSG1; RBM37; Serine/arginine-rich splicing factor 7; Splicing factor 9G8; Splicing factor; Splicing factor, arginine/serine rich 7; SRSF7; SRSF7_HUMAN; ZCCHC20; ZCRB2
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-238
  • 氨基酸序列
    MSRYGRYGGE TKVYVGNLGT GAGKGELERA FSYYGPLRTV WIARNPPGFA FVEFEDPRDA EDAVRGLDGK VICGSRVRVE LSTGMPRRSR FDRPPARRPF DPNDRCYECG EKGHYAYDCH RYSRRRRSRS RSRSHSRSRG RRYSRSRSRS RGRRSRSASP RRSRSISLRR SRSASLRRSR SGSIKGSRYF QSPSRSRSRS RSISRPRSSR SKSRSPSPKR SRSPSGSPRR SASPERMD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.
  • 基因功能參考文獻：
    1. role of SRSF7 in cell proliferation through regulating p21 levels. PMID: 27644562
    2. SRSF7 expression in cancer cells is regulated by microRNAs: short, non-coding RNAs that bind to 3'UTR of target genes and downregulate their expression. SRSF7 regulate proliferation of renal cancer cells.SRSF7 regulates expression of osteopontin. PMID: 27664584
    3. Genome-wide identification of CD95 antigen alternative splicing regulators, such as SRSF7, reveals links with iron homeostasis. PMID: 25482508
    4. Coexpression of Dyrk1A and splicing factor 9G8 leads to their translocation from the nucleus to the cytoplasm and suppresses their ability to regulate tau exon 10 splicing. PMID: 21215488
    5. Cyclic AMP-dependent protein kinase regulates 9G8-mediated alternative splicing of tau exon 10 PMID: 22677170
    6. Upregulation of total tau expression (SFRS7-independent) and tau exon 10 splicing (SFRS7-dependent), as shown in this study to be both affected by STOX1A, is known to have implications in neurodegeneration. PMID: 21755018
    7. These results indicate that 9G8 plays a key role in regulation of exon 10 splicing and imply a pathogenic role in neurodegenerative diseases. PMID: 17137791
    8. 9G8 was shown to enhance expression of unspliced RNA containing either the Mason-Pfizer monkey virus constitutive transport element PMID: 17513303
    9. eIF3f mediates restriction of HIV-1 expression through a set of factors that includes eIF3f, the SR protein 9G8, and the cyclin-dependent kinase 11 (CDK11). PMID: 19854136

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Splicing factor SR family
  • 組織特異性：
    Brain, liver, kidney and lung.
  • 數據庫鏈接：

    HGNC: 10789

    OMIM: 600572

    KEGG: hsa:6432

    STRING: 9606.ENSP00000325905

    UniGene: Hs.309090



主站蜘蛛池模板： 男人猛躁进女人免费播放| 久久精品国产第一区二区三区| 亚洲欧美人高清精品a∨| 久久性色av亚洲电影| 天天躁日日躁狠狠躁av麻豆男男| 日本亚洲色大成网站www| 欧美 国产 亚洲视频| 亚洲国内成人精品网| 国产婷婷色一区二区三区 | 精品久久久久久无码免费| 亚洲日本在线在线看片| 久久精品国产亚洲αv忘忧草| 国产午夜福利短视频| 国产又爽又黄又不遮挡视频| 国产精品欧美成人片| 丰满少妇大力进入| 在厨房被c到高潮a毛片奶水| 国内精品九九久久久精品| 国产偷国产偷亚洲清高孕妇| 国产欧美精品区一区二区三区| 又紧又大又爽精品一区二区| 日韩乱码在线观看免费视频网站| 无码人妻少妇精品无码专区漫画 | 天天爱天天做久久狼狼| 加勒比久久综合网天天| 欧洲-级毛片内射| 九九九精品成人免费视频| 精品无码国产一区二区三区av| 欧美成人看片一区二区三区尤物| 日韩在线一区二区不卡视频| 久久精品九九亚洲精品天堂| 久久人妻av一区二区软件| 国内精品久久久久影院薰衣草 | 97夜夜澡人人爽人人模人人喊| 国产精品人成视频免费999| 97免费公开在线视频| 无码人妻丝袜在线视频红杏| 国产亚洲婷婷香蕉久久精品| 国产综合色在线视频区| 国产精品国产对白熟妇| 久久久久成人片免费观看蜜芽|