在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SRSF7 Antibody

SRSF7 Antibody

  • 中文名稱：
    SRSF7兔多克隆抗體
  • 貨號(hào)：
    CSB-PA000772
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HuvEc cells using 9G8 Polyclonal Antibody
    • Western Blot analysis of HuvEc cells using 9G8 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    SRSF7
  • 別名：
    9G8 antibody; AAG3 antibody; arginine/serine-rich 7 antibody; HSSG1 antibody; RBM37 antibody; Serine/arginine-rich splicing factor 7 antibody; Splicing factor 9G8 antibody; Splicing factor antibody; Splicing factor, arginine/serine rich 7 antibody; SRSF7 antibody; SRSF7_HUMAN antibody; ZCCHC20 antibody; ZCRB2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human 9G8.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.
  • 基因功能參考文獻(xiàn)：
    1. role of SRSF7 in cell proliferation through regulating p21 levels. PMID: 27644562
    2. SRSF7 expression in cancer cells is regulated by microRNAs: short, non-coding RNAs that bind to 3'UTR of target genes and downregulate their expression. SRSF7 regulate proliferation of renal cancer cells.SRSF7 regulates expression of osteopontin. PMID: 27664584
    3. Genome-wide identification of CD95 antigen alternative splicing regulators, such as SRSF7, reveals links with iron homeostasis. PMID: 25482508
    4. Coexpression of Dyrk1A and splicing factor 9G8 leads to their translocation from the nucleus to the cytoplasm and suppresses their ability to regulate tau exon 10 splicing. PMID: 21215488
    5. Cyclic AMP-dependent protein kinase regulates 9G8-mediated alternative splicing of tau exon 10 PMID: 22677170
    6. Upregulation of total tau expression (SFRS7-independent) and tau exon 10 splicing (SFRS7-dependent), as shown in this study to be both affected by STOX1A, is known to have implications in neurodegeneration. PMID: 21755018
    7. These results indicate that 9G8 plays a key role in regulation of exon 10 splicing and imply a pathogenic role in neurodegenerative diseases. PMID: 17137791
    8. 9G8 was shown to enhance expression of unspliced RNA containing either the Mason-Pfizer monkey virus constitutive transport element PMID: 17513303
    9. eIF3f mediates restriction of HIV-1 expression through a set of factors that includes eIF3f, the SR protein 9G8, and the cyclin-dependent kinase 11 (CDK11). PMID: 19854136

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    Splicing factor SR family
  • 組織特異性：
    Brain, liver, kidney and lung.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 10789

    OMIM: 600572

    KEGG: hsa:6432

    STRING: 9606.ENSP00000325905

    UniGene: Hs.309090



主站蜘蛛池模板： 国产亚洲曝欧美曝妖精品| 午夜私人成年影院| 久久精品香蕉绿巨人登场| 18禁美女裸体无遮挡免费观看国产| 欧美日韩在线视频一区| 两个人看的www在线观看| 人与人性恔配视频免费| 日本人妻精品免费视频| 天天av天天翘天天综合网色鬼| 全球av集中精品导航福利| 熟女熟妇伦av网站| 亚洲国产成人精品激情姿源 | 人人人插人人费| 午夜一区二区亚洲福利| 又粗又大内射免费视频小说| 欧美熟妇的性裸交| 欧美巨波霸乳影院| 无码国产精品高清免费| 国产亚洲曝欧美不卡精品| 麻豆高清免费国产一区| 人人爽人人爽人人片a| 青娱国产区在线| 国产天堂亚洲国产碰碰| 性欧美激情aa片在线播放| 无码中文字幕人妻在线一区| 亚洲一区二区av在线观看| 国产精品老热丝在线观看| 亚洲精品无码av黄瓜影视| 私人家庭影院5777| 熟女性饥渴一区二区三区| 色偷一区国产精品| 国内精品九九久久久精品| 亚州性无码不卡免费视频| 中文字字幕人妻中文| 7m精品福利视频导航| 国产ktv交换配乱婬视频| 又大又硬又黄的免费视频| 国产成人一区二区三区别| 草草影院精品一区二区三区| 亚洲bbw性色大片| 性裸交a片一区二区三区|