在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Semaphorin-3C (SEMA3C)

  • 中文名稱(chēng):
    人SEMA3C重組蛋白
  • 貨號(hào):
    CSB-YP860786HU
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
    人SEMA3C重組蛋白
  • 貨號(hào):
    CSB-EP860786HU
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
    人SEMA3C重組蛋白
  • 貨號(hào):
    CSB-EP860786HU-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
    人SEMA3C重組蛋白
  • 貨號(hào):
    CSB-BP860786HU
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
    人SEMA3C重組蛋白
  • 貨號(hào):
    CSB-MP860786HU
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SEMA3C
  • Uniprot No.:
  • 別名:
    SEMA3C; SEMAE; Semaphorin-3C; Semaphorin-E; Sema E
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    full length protein
  • 表達(dá)區(qū)域:
    21-751
  • 氨基酸序列
    GSSQPQARVY LTFDELRETK TSEYFSLSHH PLDYRILLMD EDQDRIYVGS KDHILSLNIN NISQEALSVF WPASTIKVEE CKMAGKDPTH GCGNFVRVIQ TFNRTHLYVC GSGAFSPVCT YLNRGRRSED QVFMIDSKCE SGKGRCSFNP NVNTVSVMIN EELFSGMYID FMGTDAAIFR SLTKRNAVRT DQHNSKWLSE PMFVDAHVIP DGTDPNDAKV YFFFKEKLTD NNRSTKQIHS MIARICPNDT GGLRSLVNKW TTFLKARLVC SVTDEDGPET HFDELEDVFL LETDNPRTTL VYGIFTTSSS VFKGSAVCVY HLSDIQTVFN GPFAHKEGPN HQLISYQGRI PYPRPGTCPG GAFTPNMRTT KEFPDDVVTF IRNHPLMYNS IYPIHKRPLI VRIGTDYKYT KIAVDRVNAA DGRYHVLFLG TDRGTVQKVV VLPTNNSVSG ELILEELEVF KNHAPITTMK ISSKKQQLYV SSNEGVSQVS LHRCHIYGTA CADCCLARDP YCAWDGHSCS RFYPTGKRRS RRQDVRHGNP LTQCRGFNLK AYRNAAEIVQ YGVKNNTTFL ECAPKSPQAS IKWLLQKDKD RRKEVKLNER IIATSQGLLI RSVQGSDQGL YHCIATENSF KQTIAKINFK VLDSEMVAVV TDKWSPWTWA SSVRALPFHP KDIMGAFSHS EMQMINQYCK DTRQQHQQGD ESQKMRGDYG KLKALINSRK SRNRRNQLPE S
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance.
  • 基因功能參考文獻(xiàn):
    1. in situ hybridization analysis revealed that Sema 3C and Sema 3F are expressed at the RNA level in the endometriosis affected peritoneum PMID: 27558236
    2. Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner in prostate tumor cells. PMID: 28038451
    3. The exploratory genome-wide association studies confirmed APOE and identified the novel loci: rs2525776 near SEMA3C (P = 1 x 10(-8), OR = 3.3 [2.1-5.1]). PMID: 26993346
    4. Aberrant expression of sema3c is correlated with poor prognosis of pancreatic ductal adenocarcinoma patients and promotes tumor growth and metastasis by activating ERK1/2 signaling pathway. PMID: 28315433
    5. FR-sema3C could perhaps be used for the treatment of AMD. PMID: 28036336
    6. SEMA3C plays a role in the progression of breast cancer and may positively influence breast cancer cell adhesion, invasion and proliferation, as well as being associated with grade of disease and estrogen receptor status. PMID: 26977026
    7. Data show significant increases in semaphorin3C, 3D and their receptor neuropilin-2 in degenerate samples which were shown to contain nerves and blood vessels, compared to non-degenerate samples without nerves and blood vessels. PMID: 26286962
    8. Increased levels of Sema3C protein may be associated with the progression of glioma tumor and have potential as a prognostic marker for outcome of glioma patients. PMID: 26032848
    9. SEMA3C expression increased in the transition from normal to malignant breast lesions and correlated with microvessel density and tumour grade and is differentially regulated in the development of breast versus oral neoplasia. PMID: 25910410
    10. Glioma stem cells preferentially secrete Sema3C and coordinately express PlexinA2/D1 receptors to activate Rac1/nuclear factor (NF)-kB signaling. PMID: 25464848
    11. p65-Sema3C, but not FR-sema3C, rendered A549 lung cancer cells resistant to serum deprivation, suggesting that previously reported protumorigenic activities of sema3C may be due to p65-Sema3C produced by tumor cells PMID: 25808871
    12. Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability. PMID: 25839327
    13. SEMA3C is a novel adipokine regulated by weight changes. PMID: 23666167
    14. Capillary-like tubular formation was reduced by the addition of culture media of sema3C miRNA cells. PMID: 22924992
    15. The role of the motoneuronal Sema3 code could be to set population-specific axon sensitivity to limb-derived chemotropic Sema3 proteins, therefore specifying stereotyped motor nerve trajectories in their target field. PMID: 22899844
    16. cleavage of semaphorin 3C induced by ADAMTS1 promotes the migration of breast cancer cells, indicating that the co-expression of these molecules in tumors may contribute to the metastatic program PMID: 19915008
    17. correlation of gene expression with histopathological findings and clinical outcome in ovarian and breast cancer patients PMID: 12174914
    18. S3C from macrophages and fibroblasts, which is selectively directed against sympathetic nerve fibers, could be one element responsible for reduced sympathetic innervation in rheumatoid arthritis tissue PMID: 15077297
    19. mutations in GATA6 are genetic causes of congenital heart diseases involving outflow tract defects, as a result of the disruption of the direct regulation of semaphorin 3C-plexin A2 signaling PMID: 19666519

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Semaphorin family
  • 組織特異性:
    Expressed intensely in the heart, skeletal muscle, colon, small intestine, ovary, testis, and prostate. Faint expression ubiquitously among other organs, including brain.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 10725

    OMIM: 602645

    KEGG: hsa:10512

    STRING: 9606.ENSP00000265361

    UniGene: Hs.269109



主站蜘蛛池模板: 偷拍农村老熟妇xxxxx7视频| 欧美孕妇乳喷奶水在线观看| 久久久亚洲欧洲日产国码αv| 国语自产拍精品香蕉在线播放| 六月丁香亚洲综合在线视频| 亚洲精品无码aⅴ中文字幕蜜桃| 手机看片久久国产免费| 亚洲一区二区三区影院| 美女裸体自慰在线观看| 欧美一性一乱一交一视频| 无码国产玉足脚交极品播放| 久久久久国色av∨免费看| 国产av一区二区精品久久凹凸| 亚洲色大成网站www久久九| 日韩va中文字幕无码电影| 樱花草在线社区www韩国| 无码国产激情在线观看| 少妇呻吟白浆高潮啪啪69| av制服丝袜白丝国产网站| 大肉大捧一进一出好爽| 熟妇人妻av无码一区二区三区| 亚洲综合av色婷婷| 97人妻免费碰视频碰免| 色琪琪av中文字幕一区二区| 久久av无码精品人妻出轨| 九九久久精品国产av片国产| 婷婷色中文字幕综合在线| 男女啪啪免费观看的网址| 伊人精品无码av一区二区三区| 亚洲乱码卡一卡二卡新区中国 | 激情综合婷婷色五月蜜桃 | 人妻少妇heyzo无码专区| 人妻中文字幕无码系列| 鲁一鲁一鲁一鲁一曰综合网| 国产精品综合av一区二区国产馆| 黑人巨大精品欧美黑寡妇| 国产欧美另类久久精品蜜芽| 综合在线视频精品专区| 无码人妻专区免费视频| 丰满熟妇人妻av无码区| 巨爆乳无码视频在线观看|