在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SEMA3C Antibody, Biotin conjugated

  • 中文名稱:
    SEMA3C兔多克隆抗體, Biotin偶聯(lián)
  • 貨號:
    CSB-PA860786LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) SEMA3C Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    SEMA3C
  • 別名:
    SEMA3C antibody; SEMAE antibody; Semaphorin-3C antibody; Semaphorin-E antibody; Sema E antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Semaphorin-3C protein (292-396AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance.
  • 基因功能參考文獻:
    1. in situ hybridization analysis revealed that Sema 3C and Sema 3F are expressed at the RNA level in the endometriosis affected peritoneum PMID: 27558236
    2. Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner in prostate tumor cells. PMID: 28038451
    3. The exploratory genome-wide association studies confirmed APOE and identified the novel loci: rs2525776 near SEMA3C (P = 1 x 10(-8), OR = 3.3 [2.1-5.1]). PMID: 26993346
    4. Aberrant expression of sema3c is correlated with poor prognosis of pancreatic ductal adenocarcinoma patients and promotes tumor growth and metastasis by activating ERK1/2 signaling pathway. PMID: 28315433
    5. FR-sema3C could perhaps be used for the treatment of AMD. PMID: 28036336
    6. SEMA3C plays a role in the progression of breast cancer and may positively influence breast cancer cell adhesion, invasion and proliferation, as well as being associated with grade of disease and estrogen receptor status. PMID: 26977026
    7. Data show significant increases in semaphorin3C, 3D and their receptor neuropilin-2 in degenerate samples which were shown to contain nerves and blood vessels, compared to non-degenerate samples without nerves and blood vessels. PMID: 26286962
    8. Increased levels of Sema3C protein may be associated with the progression of glioma tumor and have potential as a prognostic marker for outcome of glioma patients. PMID: 26032848
    9. SEMA3C expression increased in the transition from normal to malignant breast lesions and correlated with microvessel density and tumour grade and is differentially regulated in the development of breast versus oral neoplasia. PMID: 25910410
    10. Glioma stem cells preferentially secrete Sema3C and coordinately express PlexinA2/D1 receptors to activate Rac1/nuclear factor (NF)-kB signaling. PMID: 25464848
    11. p65-Sema3C, but not FR-sema3C, rendered A549 lung cancer cells resistant to serum deprivation, suggesting that previously reported protumorigenic activities of sema3C may be due to p65-Sema3C produced by tumor cells PMID: 25808871
    12. Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability. PMID: 25839327
    13. SEMA3C is a novel adipokine regulated by weight changes. PMID: 23666167
    14. Capillary-like tubular formation was reduced by the addition of culture media of sema3C miRNA cells. PMID: 22924992
    15. The role of the motoneuronal Sema3 code could be to set population-specific axon sensitivity to limb-derived chemotropic Sema3 proteins, therefore specifying stereotyped motor nerve trajectories in their target field. PMID: 22899844
    16. cleavage of semaphorin 3C induced by ADAMTS1 promotes the migration of breast cancer cells, indicating that the co-expression of these molecules in tumors may contribute to the metastatic program PMID: 19915008
    17. correlation of gene expression with histopathological findings and clinical outcome in ovarian and breast cancer patients PMID: 12174914
    18. S3C from macrophages and fibroblasts, which is selectively directed against sympathetic nerve fibers, could be one element responsible for reduced sympathetic innervation in rheumatoid arthritis tissue PMID: 15077297
    19. mutations in GATA6 are genetic causes of congenital heart diseases involving outflow tract defects, as a result of the disruption of the direct regulation of semaphorin 3C-plexin A2 signaling PMID: 19666519

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Semaphorin family
  • 組織特異性:
    Expressed intensely in the heart, skeletal muscle, colon, small intestine, ovary, testis, and prostate. Faint expression ubiquitously among other organs, including brain.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 10725

    OMIM: 602645

    KEGG: hsa:10512

    STRING: 9606.ENSP00000265361

    UniGene: Hs.269109



主站蜘蛛池模板: 成人乱码一区二区三区四区 | 尤物193在线人妻精品免费| 狠狠噜天天噜日日噜色综合| 老子影院午夜伦手机不四虎卡| 中文字幕精品亚洲无线码一区| 午夜理论片yy8860y影院| 国产精品午夜福利不卡120| 无码纯肉动漫在线观看| 永久免费不卡在线观看黄网站| 国产乱国产乱老熟300部视频| 国产成人精品福利一区二区三区| 久久婷婷久久一区二区三区| 精品乱码一区二区三区四区| 欧美v国产v亚洲v日韩九九| 国产九九99久久99大香伊| 成人3d动漫一区二区三区| 在线播放免费人成毛片乱码| 天堂最新版在线www官网中文地址| 啦啦啦www在线观看免费视频| 色播亚洲视频在线观看| 亚洲欧美成人综合图区| 国产成人久久av免费| 成熟老妇女视频| 欧美亚洲国产精品久久蜜芽| 蜜臀视频一区二区在线播放| 97人妻天天摸天天爽天天| 高清无码视频直接看| 一本色道久久综合亚州精品蜜桃| 国产成人高清精品亚洲| 国产av无码专区亚洲a∨毛片| 久久精品亚洲精品国产色婷| 国产爽视频在线观看视频| 免费人成视频在线观看网站| 午夜精品久久久久久久久| 午夜性色吃奶添下面69影院| 日韩欧美群交p片內射中文| 久久人人爽人人爽人人片| 伊人久久大香线蕉在观看| 免费看成人毛片无码视频| 欧美肥胖老妇bbw| 尤物yw午夜国产精品大臿蕉|