在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human SHC-transforming protein 4 (SHC4)

  • 中文名稱:
    人SHC4重組蛋白
  • 貨號:
    CSB-YP747568HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SHC4重組蛋白
  • 貨號:
    CSB-EP747568HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SHC4重組蛋白
  • 貨號:
    CSB-EP747568HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SHC4重組蛋白
  • 貨號:
    CSB-BP747568HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SHC4重組蛋白
  • 貨號:
    CSB-MP747568HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    hShcD; MGC34023; Rai like protein; Rai-like protein; RaLP; SH2 domain protein C4; SHC (Src homology 2 domain containing) family member 4; SHC 4; SHC adaptor protein 4; SHC; SHC family member 4; SHC transforming protein 4; SHC transforming protein D; SHC-transforming protein 4; SHC-transforming protein D; Shc4; SHC4_HUMAN; SHCD; Src homology 2 domain containing family member 4; Src homology 2 domain containing transforming protein C4; Src homology 2 domain-containing-transforming protein C4
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-630
  • 氨基酸序列
    MRERGQDSLA GLVLYVGLFG HPGMLHRAKY SRFRNESITS LDEGSSGGSV GNKGSPQPPH PALAPHLPTE DATLPSQESP TPLCTLIPRM ASMKLANPAT LLSLKNFCLG TKEVPRLKLQ ESRDPGSSGP SSPETSLSRS GTAPPPQQDL VGHRATALTP DSCPLPGPGE PTLRSRQDRH FLQHLLGMGM NYCVRYMGCV EVLQSMRSLD FGMRTQVTRE AISRLCEAVP GANGAIKKRK PPVKFLSTVL GKSNLQFSGM NIKLTISTCS LTLMNLDNQQ IIANHHMQSI SFASGGDPDT TDYVAYVAKD PVNQRACHIL ECHNGMAQDV ISTIGQAFEL RFKQYLKNPS LNTSCESEEV HIDSHAEERE DHEYYNEIPG KQPPVGGVSD MRIKVQATEQ MAYCPIQCEK LCYLPGNSKC SSVYENCLEQ SRAIGNVHPR GVQSQRDTSL LKHTCRVDLF DDPCYINTQA LQSTPGSAGN QRSAQPLGSP WHCGKAPETV QPGATAQPAS SHSLPHIKQQ LWSEECYHGK LSRKAAESLL VKDGDFLVRE SATSPGQYVL SGLQGGQAKH LLLVDPEGKV RTKDHVFDNV GHLIRYHMDN SLPIISSGSE VSLKQPVRKD NNPALLHSNK
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.
  • 基因功能參考文獻:
    1. ShcD appears to possess several molecular permutations that actively govern the EGFR, which may have implications in development and disease. PMID: 28724758
    2. ShcD binds to active Ret, TrkA, and TrkB neurotrophic factor receptors predominantly via its phosphotyrosine-binding (PTB) domain. PMID: 28213521
    3. The ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor. PMID: 24430869
    4. ShcD can exist within the nucleus, and its CH2 domain has a critical role in nuclear export of ShcD. PMID: 24036217
    5. ShcD binds to TrkC in a kinase-activity-dependent manner through its PTB and SH2 domains. PMID: 20078941
    6. ShcD interacts with TrkB in a kinase-activity-dependent manner. PMID: 20663410
    7. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    8. A new member of the Shc family of docking proteins is characterised, which may mediate a specific aspect of signaling downstream of the MuSK receptor. PMID: 17452444

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell junction, synapse, postsynaptic cell membrane.
  • 組織特異性:
    Only expressed in melanomas. Weakly expressed in normal melanocytes and benign nevi. Highly expressed at the transition from radial growth phase to vertical growth phase and metastatic melanomas, when tumor cells acquire migratory competence and invasive
  • 數(shù)據(jù)庫鏈接:

    HGNC: 16743

    OMIM: 617372

    KEGG: hsa:399694

    STRING: 9606.ENSP00000329668

    UniGene: Hs.642615



主站蜘蛛池模板: 国产白丝精品爽爽久久久久久蜜臀| 久久不见久久见免费视频6无删减| 免费观看亚洲人成网站| 少妇人妻中文字幕污| 成人亚洲欧美一区二区三区| 成人精品一区二区三区电影| 四库影院永久四虎精品国产 | aaaaa少妇高潮大片| 东京无码熟妇人妻av在线网址| 精品国产第一福利网站| 亚洲伊人丝袜精品久久| 亚洲精品成人久久久| 国产欧美精品一区二区色综合| 美女扒开奶罩露出奶头视频网站 | 永久免费毛片在线播放| www国产内插视频| 无码人妻精一区二区三区| 免费午夜福利不卡片在线播放| 人妻无码久久中文字幕专区 | 亚洲人成电影在线天堂色| 天天躁夜夜躁狠狠躁2020| 无码精品一区二区三区在线| 日韩精品一区二区午夜成人版| 2023国产精品一卡2卡三卡4卡| 伊人成伊人成综合网222| 亚洲有无码av在线播放| 天天射寡妇射| 国产精品三级一区二区| 狠狠色噜噜狠狠狠狠777米奇小说| 免费做a爰片久久毛片a片下载| 久久精品成人免费国产| 乱子轮熟睡1区| 人与禽交videos欧美| 国产午夜精品一区二区三区四区| 亚洲成av人片在www鸭子| 日韩综合亚洲色在线影院| 一二三区乱码不卡手机版| 欧美成人精品手机在线| 精品国产亚洲一区二区三区| 夜夜爽妓女8888888视频| 欧美日韩国产中文高清视频|