在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SHC4 Antibody

  • 中文名稱:
    SHC4兔多克隆抗體
  • 貨號:
    CSB-PA747568ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: SHC4 antibody at 6μg/ml + Jurkat whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 69, 43 kDa
      Observed band size: 69 kDa
    • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA747568ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) SHC4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    hShcD antibody; MGC34023 antibody; Rai like protein antibody; Rai-like protein antibody; RaLP antibody; SH2 domain protein C4 antibody; SHC (Src homology 2 domain containing) family member 4 antibody; SHC 4 antibody; SHC adaptor protein 4 antibody; SHC antibody; SHC family member 4 antibody; SHC transforming protein 4 antibody; SHC transforming protein D antibody; SHC-transforming protein 4 antibody; SHC-transforming protein D antibody; Shc4 antibody; SHC4_HUMAN antibody; SHCD antibody; Src homology 2 domain containing family member 4 antibody; Src homology 2 domain containing transforming protein C4 antibody; Src homology 2 domain-containing-transforming protein C4 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human SHC-transforming protein 4 protein (1-185AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.
  • 基因功能參考文獻:
    1. ShcD appears to possess several molecular permutations that actively govern the EGFR, which may have implications in development and disease. PMID: 28724758
    2. ShcD binds to active Ret, TrkA, and TrkB neurotrophic factor receptors predominantly via its phosphotyrosine-binding (PTB) domain. PMID: 28213521
    3. The ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor. PMID: 24430869
    4. ShcD can exist within the nucleus, and its CH2 domain has a critical role in nuclear export of ShcD. PMID: 24036217
    5. ShcD binds to TrkC in a kinase-activity-dependent manner through its PTB and SH2 domains. PMID: 20078941
    6. ShcD interacts with TrkB in a kinase-activity-dependent manner. PMID: 20663410
    7. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    8. A new member of the Shc family of docking proteins is characterised, which may mediate a specific aspect of signaling downstream of the MuSK receptor. PMID: 17452444

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell junction, synapse, postsynaptic cell membrane.
  • 組織特異性:
    Only expressed in melanomas. Weakly expressed in normal melanocytes and benign nevi. Highly expressed at the transition from radial growth phase to vertical growth phase and metastatic melanomas, when tumor cells acquire migratory competence and invasive
  • 數據庫鏈接:

    HGNC: 16743

    OMIM: 617372

    KEGG: hsa:399694

    STRING: 9606.ENSP00000329668

    UniGene: Hs.642615



主站蜘蛛池模板: 欧美一性一乱一交一免费视频| 中文天堂国产最新| 国产成人无码av| 久久超碰97人人做人人爱| 亚洲精品一区二区精华液| 亚洲の无码国产の无码步美| 亚洲欧洲精品成人久久曰| 老子午夜精品无码| av蓝导航精品导航| 成年无码动漫av片在线尤物网站 | 国产精品三级一区二区| 一区二区乱子伦在线播放| 樱花草在线社区www韩国 | √8天堂资源地址中文在线| 无码专区视频精品老司机| 久久久久久人妻精品一区| 国产高清在线a视频大全| 日本一道综合久久aⅴ久久| 12裸体自慰免费观看网站| 国产真人作爱免费视频道歉| 欧美精品黑人粗大视频| 少妇愉情理伦片高潮日本| 国产毛片一区二区精品| 精品国产中文字幕在线视频| 人人爽人人爱| 国产激情无码一区二区三区| 强制高潮18xxxx按摩| 国产精品99爱免费视频| 亚洲成a v人片在线观看| 成在线人免费无码高潮喷水| 亚洲中文无码人a∨在线导航| 午夜福利不卡片在线机免费视频| 国产精品综合av一区二区国产馆| 欧美乱人伦人妻中文字幕| √天堂资源地址在线官网| 18禁无遮挡肉动漫在线播放观看 | 国产精品久久久久久久久久久久人四虎| 久久久久久国产精品无码超碰| 国内精品国语自产拍在线观看 | 成熟女人牲交片免费观看视频| 日本不卡三区|