在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human SH2 domain-containing protein 3C (SH2D3C), partial

  • 中文名稱:
    人SH2D3C重組蛋白
  • 貨號:
    CSB-YP839802HU
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SH2D3C重組蛋白
  • 貨號:
    CSB-EP839802HU
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SH2D3C重組蛋白
  • 貨號:
    CSB-EP839802HU-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SH2D3C重組蛋白
  • 貨號:
    CSB-BP839802HU
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SH2D3C重組蛋白
  • 貨號:
    CSB-MP839802HU
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SH2D3C
  • Uniprot No.:
  • 別名:
    Cas/HEF1 associated signal transducer; CHAT; FLJ39664; Novel SH2 containing protein 3; Novel SH2-containing protein 3; NSP 3; PRO34088; SH2 domain containing 3C ; SH2 domain containing Eph receptor binding protein 1; SH2 domain containing protein 3C; SH2 domain-containing protein 3C; SH2D3_HUMAN; SH2D3C; Shep1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as an adapter protein that mediates cell signaling pathways involved in cellular functions such as cell adhesion and migration, tissue organization, and the regulation of the immune response. Plays a role in integrin-mediated cell adhesion through BCAR1-CRK-RAPGEF1 signaling and activation of the small GTPase RAP1. Promotes cell migration and invasion through the extracellular matrix. Required for marginal zone B-cell development and thymus-independent type 2 immune responses. Mediates migration and adhesion of B cells in the splenic marginal zone via promoting hyperphosphorylation of NEDD9/CASL. Plays a role in CXCL13-induced chemotaxis of B-cells. Plays a role in the migration of olfactory sensory neurons (OSNs) into the forebrain and the innervation of the olfactory bulb by the OSN axons during development. Required for the efficient tyrosine phosphorylation of BCAR1 in OSN axons.; Important regulator of chemokine-induced, integrin-mediated T lymphocyte adhesion and migration, acting upstream of RAP1. Required for tissue-specific adhesion of T lymphocytes to peripheral tissues. Required for basal and CXCL2 stimulated serine-threonine phosphorylation of NEDD9. May be involved in the regulation of T-cell receptor-mediated IL2 production through the activation of the JNK pathway in T-cells.; May be involved in the BCAR1/CAS-mediated JNK activation pathway.
  • 基因功能參考文獻:
    1. The structure of the NSP3-p130Cas complex reveals that this closed conformation is instrumental for interaction of NSP proteins with a focal adhesion-targeting domain present in Cas proteins. PMID: 22081014
    2. This protein positively regulates T cell receptor-mediated interleukin-2 production by Jurkat cells. PMID: 12486027
    3. SH2D3C (SHEP1) is less highly expressed than BCAR3 and NSP1 in breast cancer cells, and the expression patterns suggest differential roles for the three genes during breast cancer progression. PMID: 17270363
    4. NSP3 overexpression did not induce anti-estrogen resistance in breast tumor cell lines. PMID: 17427198
  • 亞細胞定位:
    Cytoplasm. Cell membrane; Peripheral membrane protein. Cell projection, axon. Cell projection, ruffle membrane.; [Isoform 1]: Cell membrane; Peripheral membrane protein.
  • 組織特異性:
    [Isoform 1]: Ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 16884

    OMIM: 604722

    KEGG: hsa:10044

    STRING: 9606.ENSP00000317817

    UniGene: Hs.306412



主站蜘蛛池模板: 亚洲熟女综合一区二区三区| 加勒比久久综合网天天| 美女内射毛片在线看免费人动物| av成人无码无在线观看| 色综合天天天天综合狠狠爱| 99精品无人区乱码1区2区3区 | 欧美极品色午夜在线视频 | 亚洲国产欧美在线成人app| 亚洲男人最新版本天堂| 凹凸国产熟女精品视频app| 免费国产va在线观看| 韩国 欧美 日产 国产精品| 久久精品成人亚洲另类欧美| 少妇高潮太爽了在线视频| 免费的黄网站在线观看| 久久er热在这里只有精品66| 国产日韩在线视看高清视频手机| 无码人妻丰满熟妇a片护士| 国产韩国精品一区二区三区久久| 久久亚洲精品ab无码播放| 高清同性男毛片| 最新国产在线拍揄自揄视频| 精品一区二区三区无码视频| 在线 无码 中文字幕 强 乱| 国产成人av乱码免费观看| 国产欧美va天堂在线观看视频下载| 精品夜夜澡人妻无码av蜜桃| 久久亚洲精品情侣| 国产真实乱对白精彩久久| 国产人久久人人人人爽| 亚洲国产精彩中文乱码av| 又大又粗又爽免费视频a片| 久久久久亚洲精品| 起碰免费公开97在线视频| 午夜免费啪视频在线18| 国产亚洲精品欧洲在线观看| 日韩少妇内射免费播放18禁裸乳 | 成年无码a√片在线观看| 亚洲色婷婷久久精品av蜜桃久久| 伊人成年网站综合网| 国语对白嫖老妇胖老太|