在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

SH2D3C Antibody

  • 中文名稱:
    SH2D3C兔多克隆抗體
  • 貨號:
    CSB-PA021213GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    SH2D3C
  • 別名:
    Cas/HEF1 associated signal transducer antibody; CHAT antibody; FLJ39664 antibody; Novel SH2 containing protein 3 antibody; Novel SH2-containing protein 3 antibody; NSP 3 antibody; PRO34088 antibody; SH2 domain containing 3C antibody; SH2 domain containing Eph receptor binding protein 1 antibody; SH2 domain containing protein 3C antibody; SH2 domain-containing protein 3C antibody; SH2D3_HUMAN antibody; SH2D3C antibody; Shep1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human SH2D3C
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Acts as an adapter protein that mediates cell signaling pathways involved in cellular functions such as cell adhesion and migration, tissue organization, and the regulation of the immune response. Plays a role in integrin-mediated cell adhesion through BCAR1-CRK-RAPGEF1 signaling and activation of the small GTPase RAP1. Promotes cell migration and invasion through the extracellular matrix. Required for marginal zone B-cell development and thymus-independent type 2 immune responses. Mediates migration and adhesion of B cells in the splenic marginal zone via promoting hyperphosphorylation of NEDD9/CASL. Plays a role in CXCL13-induced chemotaxis of B-cells. Plays a role in the migration of olfactory sensory neurons (OSNs) into the forebrain and the innervation of the olfactory bulb by the OSN axons during development. Required for the efficient tyrosine phosphorylation of BCAR1 in OSN axons.; Important regulator of chemokine-induced, integrin-mediated T lymphocyte adhesion and migration, acting upstream of RAP1. Required for tissue-specific adhesion of T lymphocytes to peripheral tissues. Required for basal and CXCL2 stimulated serine-threonine phosphorylation of NEDD9. May be involved in the regulation of T-cell receptor-mediated IL2 production through the activation of the JNK pathway in T-cells.; May be involved in the BCAR1/CAS-mediated JNK activation pathway.
  • 基因功能參考文獻(xiàn):
    1. The structure of the NSP3-p130Cas complex reveals that this closed conformation is instrumental for interaction of NSP proteins with a focal adhesion-targeting domain present in Cas proteins. PMID: 22081014
    2. This protein positively regulates T cell receptor-mediated interleukin-2 production by Jurkat cells. PMID: 12486027
    3. SH2D3C (SHEP1) is less highly expressed than BCAR3 and NSP1 in breast cancer cells, and the expression patterns suggest differential roles for the three genes during breast cancer progression. PMID: 17270363
    4. NSP3 overexpression did not induce anti-estrogen resistance in breast tumor cell lines. PMID: 17427198
  • 亞細(xì)胞定位:
    Cytoplasm. Cell membrane; Peripheral membrane protein. Cell projection, axon. Cell projection, ruffle membrane.; [Isoform 1]: Cell membrane; Peripheral membrane protein.
  • 組織特異性:
    [Isoform 1]: Ubiquitously expressed.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 16884

    OMIM: 604722

    KEGG: hsa:10044

    STRING: 9606.ENSP00000317817

    UniGene: Hs.306412



主站蜘蛛池模板: 亚洲视频一区| 亚洲午夜精品a片一区二区app | 伊人精品成人久久综合| 裸体丰满白嫩大尺度尤物| 日本特黄特色aaa大片免费| 肥臀浪妇太爽了快点再快点| 亚洲在av极品无码天堂手机版| 日日摸日日碰夜夜爽无| 国产人碰人摸人爱免费视频| 国产精品久久久久7777| 日本xxxx色视频在线观看| 国产免费不卡av在线播放| 成人欧美一区二区三区| 国产日产欧洲无码视频 | av天堂午夜精品一区| 人妻丝袜中文无码av影音先锋专区 | 亚洲成在人线视av| 国产乱码日产精品bd| 尹人香蕉99久久综合网站| 久久精品青草社区| 精品国产一区av天美传媒| 人妻少妇伦在线麻豆m电影| 欧美日韩精品一区二区三区高清视频| 国产精自产拍久久久久久蜜| 亚洲欧美日韩国产综合v| 天堂va欧美ⅴa亚洲va| 中文字幕乱偷无码av先锋| 精品人妻无码一区二区三区换脸| 国产精品边做奶水狂喷无码| 中国大陆精品视频xxxx| 国产国语老龄妇女a片| 久久婷婷五月综合色首页| 午夜dy888国产精品影院| 色橹橹欧美在线观看视频高清 | 香港特级三a毛片免费观看| 樱花草在线社区www中国| 一品二品三品中文字幕| 宅男66lu国产在线观看| 高清国产在线拍揄自揄视频| 男女后式激烈动态图片| 国产一区二区三区在线蜜桃|