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Recombinant Human Ribosome biogenesis regulatory protein homolog (RRS1)

  • 中文名稱:
    人RRS1重組蛋白
  • 貨號:
    CSB-YP614879HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人RRS1重組蛋白
  • 貨號:
    CSB-EP614879HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人RRS1重組蛋白
  • 貨號:
    CSB-EP614879HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人RRS1重組蛋白
  • 貨號:
    CSB-BP614879HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人RRS1重組蛋白
  • 貨號:
    CSB-MP614879HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    RRS1
  • Uniprot No.:
  • 別名:
    Homolog of yeast ribosome biogenesis regulator; Homolog of yeast ribosome biogenesis regulatory protein RRS1; KIAA0112; OTTHUMP00000227420; Ribosome biogenesis regulatory protein homolog; Ribosome biogenesis regulatory protein RRS1 homolog; RRR; rrs1; RRS1 ribosome biogenesis regulator homolog (S. cerevisiae); RRS1_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-365
  • 氨基酸序列
    MEGQSVEELL AKAEQDEAEK LQRITVHKEL ELQFDLGNLL ASDRNPPTGL RCAGPTPEAE LQALARDNTQ LLINQLWQLP TERVEEAIVA RLPEPTTRLP REKPLPRPRP LTRWQQFARL KGIRPKKKTN LVWDEVSGQW RRRWGYQRAR DDTKEWLIEV PGNADPLEDQ FAKRIQAKKE RVAKNELNRL RNLARAHKMQ LPSAAGLHPT GHQSKEELGR AMQVAKVSTA SVGRFQERLP KEKVPRGSGK KRKFQPLFGD FAAEKKNQLE LLRVMNSKKP QLDVTRATNK QMREEDQEEA AKRRKMSQKG KRKGGRQGPG GKRKGGPPSQ GGKRKGGLGG KMNSGPPGLG GKRKGGQRPG GKRRK
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.
  • 基因功能參考文獻:
    1. These results suggest that the RRS1 gene plays a critical role in cell proliferation, colony formation, cell apoptosis and cell cycle distribution in human HCC cells, and that silencing of RRS1 by RNAi is a promising therapeutic approach for the treatment of HCC, and should be further developed PMID: 28849112
    2. RNA interference experiments revealed that RRS1-depleted cells show abnormalities in chromosome alignment and spindle organization, which result in mitotic delay. PMID: 19465021
  • 亞細胞定位:
    Nucleus, nucleolus.
  • 蛋白家族:
    RRS1 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 17083

    KEGG: hsa:23212

    STRING: 9606.ENSP00000322396

    UniGene: Hs.71827



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