在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Retinoic acid receptor RXR-gamma (RXRG)

  • 中文名稱:
    人RXRG重組蛋白
  • 貨號:
    CSB-YP020614HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人RXRG重組蛋白
  • 貨號:
    CSB-EP020614HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人RXRG重組蛋白
  • 貨號:
    CSB-EP020614HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人RXRG重組蛋白
  • 貨號:
    CSB-BP020614HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人RXRG重組蛋白
  • 貨號:
    CSB-MP020614HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    MGC109416; NR2B3; Nuclear receptor subfamily 2 group B member 3; OTTHUMP00000060418; Retanoic X receptor gamma; Retinoic acid receptor RXR gamma; Retinoic acid receptor RXR-gamma; Retinoid X receptor gamma; RXR G; RXR gamma; RXRC; Rxrg; RXRG_HUMAN; RXRgamma
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-463
  • 氨基酸序列
    MYGNYSHFMK FPAGYGGSPG HTGSTSMSPS AALSTGKPMD SHPSYTDTPV SAPRTLSAVG TPLNALGSPY RVITSAMGPP SGALAAPPGI NLVAPPSSQL NVVNSVSSSE DIKPLPGLPG IGNMNYPSTS PGSLVKHICA ICGDRSSGKH YGVYSCEGCK GFFKRTIRKD LIYTCRDNKD CLIDKRQRNR CQYCRYQKCL VMGMKREAVQ EERQRSRERA ESEAECATSG HEDMPVERIL EAELAVEPKT ESYGDMNMEN STNDPVTNIC HAADKQLFTL VEWAKRIPHF SDLTLEDQVI LLRAGWNELL IASFSHRSVS VQDGILLATG LHVHRSSAHS AGVGSIFDRV LTELVSKMKD MQMDKSELGC LRAIVLFNPD AKGLSNPSEV ETLREKVYAT LEAYTKQKYP EQPGRFAKLL LRLPALRSIG LKCLEHLFFF KLIGDTPIDT FLMEMLETPL QIT
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid.
  • 基因功能參考文獻:
    1. genetic association studies in a population in Brazil: Data suggest that SNPs in RXRG (rs2134095) and GC (rs7041) are associated with low-density lipoprotein cholesterol levels and hypercholesterolemia in the population studied; there was no apparent association with an SNP in VDR (rs2228570). (RXRG = retinoid X receptor gamma; GC = vitamin D-binding protein; VDR = vitamin D receptor) PMID: 27721113
    2. Germline mutations in the RXRG gene are linked to Familial isolated pituitary adenoma in a Brazilian Family. PMID: 27245436
    3. Data show that some rexinoids display selective coactivator (CoA) recruitment by the retinoid X receptors (RXRs) homodimer and by the heterodimers nuclear receptor Nur77/RXR and Nurr1/RXR. PMID: 26148973
    4. loss of RXR-gamma levels appears to provide mechanistic benefits to transformed cells towards the acquisition of resistance to apoptosis hallmark of cancer PMID: 23936423
    5. Genetic variation in RXRgamma gene may contribute to the development of HIVLD in combination antiretroviral therapy treated HIV patients. PMID: 23759678
    6. The RXR-gamma rs3818569 single nucleotide polymorphisms is associated with diabetic retinopathy development in the Taiwanese population. PMID: 22180072
    7. results indicate that RXR-gamma is a positive regulator of endogenous oligodendrocyte precursor cell differentiation and remyelination. PMID: 21131950
    8. methylation-associated downregulation of the RXRG gene may play a differential role in the carcinogenesis of non-small cell lung cancer (NSCLC) according to smoking status. PMID: 20113835
    9. Single nucleotide polymorphism not a factor in resistance to thyroid hormone. PMID: 15186611
    10. The retinoid X receptor, gamma expression is mainly restricted to the muscle and brain. PMID: 15608692
    11. These results show that the stimulation of ASCT2 expression in response to glutamine in part involves binding of FXR/RXR to the ASCT2 promoter. PMID: 16197915
    12. RXRgamma contributes to the genetic background of familial combined hyperlipidemia. PMID: 17272748

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 蛋白家族:
    Nuclear hormone receptor family, NR2 subfamily
  • 組織特異性:
    Expressed in aortic endothelial cells (at protein level).
  • 數據庫鏈接:

    HGNC: 10479

    OMIM: 180247

    KEGG: hsa:6258

    STRING: 9606.ENSP00000352900

    UniGene: Hs.26550



主站蜘蛛池模板: 国产精品爽黄69天堂a| 亚洲精品成a人在线观看| 日韩人妻少妇一区二区| 国产精品久久久久无码av色戒| 97午夜理论片在线影院| 亚洲a成人无m网站在线| 亚洲国产精品无码中文字| 精品乱人伦一区二区三区| 欧美疯狂做受xxxxx高潮| 69天堂人成无码免费视频| 久久亚洲精品中文字幕一区 | 97se亚洲精品一区二区| 日韩人妻精品无码一区二区三区| 国产亚洲精品久久久网站好莱| 国产日韩欧美亚洲精品中字| 国内精品美女a∨在线播放| 欧美35页视频在线观看| 亚洲精品无码国产片| 业余 自由 性别 成熟视频 视频| 国产人妻大战黑人第1集| 日韩放荡少妇无码视频| 中文字幕无码乱人伦| 男人添女人下部高潮视频| 久久精品网站免费观看| 131mm少妇做爰视频| 极品少妇xxxx| 日韩去日本高清在线| 无码视频免费一区二区三区| 99精品久久精品一区二区| 亚洲欧美日韩中文无线码| 国产亚洲aⅴ在线电影| 精品一区二区三区在线视频| 老妇女性较大毛片| 高潮内射免费看片| 在线天堂资源www在线污| 露脸叫床粗话东北少妇| 久久人人爽人人爽人人片av麻烦 | 国产成人亚洲综合色婷婷秒播| 日本少妇春药特殊按摩3| 一二三四在线观看免费视频| 亚洲日韩在线a视频在线观看|