在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Receptor-type tyrosine-protein phosphatase R (PTPRR), partial

Recombinant Human Receptor-type tyrosine-protein phosphatase R (PTPRR), partial

  • 中文名稱：
    人PTPRR重組蛋白
  • 貨號：
    CSB-YP624019HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PTPRR重組蛋白
  • 貨號：
    CSB-EP624019HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PTPRR重組蛋白
  • 貨號：
    CSB-BP624019HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PTPRR重組蛋白
  • 貨號：
    CSB-MP624019HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Ch-1PTPase; Ch1 PTPase; DKFZp781C1038; EC PTP; ECPTP; FLJ34328; MGC131968; MGC148170; NC PTPCOM1; NC-PTPCOM1; Protein tyrosine phosphatase Cr1PTPase precursor; Protein tyrosine phosphatase NC PTPCOM1; Protein tyrosine phosphatase PCPTP1; Protein tyrosine phosphatase receptor type R; Protein-tyrosine phosphatase PCPTP1; PTP SL; PTPBR7; PTPRQ; PTPRR; PTPRR_HUMAN; PTPSL; R-PTP-R; Receptor type tyrosine protein phosphatase R; Receptor-type tyrosine-protein phosphatase R
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.
  • 基因功能參考文獻：
    1. The PTPRR genes were related to possible endophenotypes for suicidal behaviour such as anger, depression-anxiety and fatigue. PMID: 28327445
    2. The development of MDD may be related with the polymorphism of ERK-rs12678428 and PTPRR-rs1513105. PMID: 28467119
    3. Results show that PTPRR is an early and direct target of the androgen receptor which negatively regulates the RAS/ERK1/2 pathway suggesting that its loss in prostate cancer cells is one factor that might contribute to activation of the RAS/ERK1/2 pathway. PMID: 25592066
    4. High expression of PTP receptors R and Z1 was observed in all examined cases of colorectal carcinoma, adenoma and normal colon tissue in this study. PMID: 24242166
    5. The methylation index of PTPRR recovered from scrapings of uterine cervix adenocarcinomas is significantly higher than in normal controls. PMID: 24407576
    6. 3 genes identified by association study and supported by ocular expression and/or replication, UHRF1BP1L, PTPRR, and PPFIA2, are novel candidates for myopic development within the MYP3 locus that should be further studied. PMID: 23422819
    7. Methylation of the PTPRR promoter has an important role in the metastasis and may be a biomarker of invasive cervical cancer PMID: 22330137
    8. the protein tyrosine phosphatase receptor type R gene may play a role in conferring risk of major depressive disorder in females PMID: 22100128
    9. expression of the PTPRR-1 isoform was inactivated in colorectal cancer cells as a result of de novo CpG island methylation and enrichment of transcription-repressive histone-tail marks, mainly H3K27me3 PMID: 20015382

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform Alpha]: Cell membrane; Single-pass type I membrane protein.; [Isoform Delta]: Cytoplasm, perinuclear region. Note=Locates to the perinuclear areas within the cytoplasm.; [Isoform Gamma]: Cytoplasm, perinuclear region. Note=Locates to the perinuclear areas within the cytoplasm.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Receptor class 7 subfamily
  • 組織特異性：
    Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta,
  • 數據庫鏈接：

    HGNC: 9680

    OMIM: 602853

    KEGG: hsa:5801

    STRING: 9606.ENSP00000283228

    UniGene: Hs.506076



主站蜘蛛池模板： 免费人成网站视频在线观看| 国产精品美女久久久久久2018| 波多野结衣网站| 在线观看成人年视频免费| 无码视频免费一区二区三区| 中国极品少妇videossexhd| 熟女人妻在线视频| 性做久久久久久免费观看| 国产性猛交普通话对白| 亚洲成本人无码薄码区| 亚洲卡一卡二乱码新区仙踪| 国产中文字字幕乱码无限| 大肉大捧一进一出好爽动态图| 亚洲欧洲成人a∨在线观看| 亚洲人成小说网站色在线观看| 香蕉久久精品日日躁夜夜躁夏| 美女露全乳无遮掩视频| 久久亚洲中文字幕精品一区| 成人看片黄a免费看| 扒开双腿疯狂进出爽爽爽视频| 欧美疯狂性受xxxxx喷水| 麻豆国产成人av在线播放| 国产精品自在在线午夜免费 | 亚洲国产av无码综合原创国产| 成人亚洲欧美激情在线电影| 小说区 图片区色 综合区| 国产精品久久久久久亚洲影视| 国产精品亚洲玖玖玖在线观看| 国产精品美女久久久久| 国产成人无码免费看片软件| 欧美不卡无线在线一二三区观| 9lporm自拍视频区| 久久99精品久久久久久水蜜桃| 国模小婕私拍鲜嫩玉门| 精品久久久久久亚洲中文字幕| 人妻va精品va欧美va| 欧美亚洲一区二区三区| 最新无码人妻在线不卡| 久久久久亚洲精品| 女人裸体性做爰视频| 久久综合久久自在自线精品自|