在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Ras-related protein Rab-12 (RAB12)

  • 中文名稱:
    人RAB12重組蛋白
  • 貨號(hào):
    CSB-YP753710HU
  • 規(guī)格:
    ¥2208
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    RAB12
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Full Length
  • 來(lái)源:
    Yeast
  • 分子量:
    28.1 kDa
  • 表達(dá)區(qū)域:
    1-244aa
  • 氨基酸序列
    MDPGAALQRRAGGGGGLGAGSPALSGGQGRRRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREITRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDILRNELSNSILSLQPEPEIPPELPPPRPHVRCC
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    C-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy.
  • 基因功能參考文獻(xiàn):
    1. DENND3 is the exchange factor for the small GTPase Rab12 regulated through an intramolecular interaction PMID: 28249939
    2. a novel signaling pathway identified whereby starvation-induced activation of ULK leads to phosphorylation of endogenous DENND3, with subsequent activation of Rab12 and initiation of membrane trafficking events required for autophagy PMID: 25925668
    3. findings demonstrate the functional importance of Rab12 for retrograde toxin trafficking PMID: 24703428
  • 亞細(xì)胞定位:
    Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Lysosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane. Cytoplasmic vesicle, autophagosome.
  • 蛋白家族:
    Small GTPase superfamily, Rab family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 31332

    OMIM: 616448

    KEGG: hsa:201475

    STRING: 9606.ENSP00000331748

    UniGene: Hs.270074



主站蜘蛛池模板: 色吊丝中文字幕| 亚洲日本中文字幕乱码在线| 亚洲日韩小电影在线观看| 国产明星裸体xxxx视频| 女人被男人躁得好爽免费视频| 99久久免费精品高清特色大片| 国产成人午夜福利在线观看| 久久国产精品国产四虎90后| av大尺度一区二区三区| 亚洲精品夜夜夜| 亚洲国产精品无码专区| 精品av中文字幕在线毛片| 一本一久本久a久久精品综合| 天天躁日日躁很很很躁| 五月天激情电影| 最新亚洲精品国偷自产在线| 影视先锋男人无码在线| 国产成人精品综合久久久| 国产成人无码国产亚洲| 无码熟妇人妻av在线影片免费| 国产乱子伦一区二区三区=| 巨大黑人极品videos精品| 老司机久久99久久精品播放 | 人妻无码手机在线中文| 日韩aⅴ人妻无码一区二区| 春色校园综合人妻av| 国产精品人妻久久毛片高清无卡| 在线播放偷拍一区精品| 污污污www精品国产网站| 熟妇人妻无乱码中文字幕真矢织江| 国色天香精品一卡2卡3卡4| 日韩无套无码精品| 欧洲熟妇色xxxx欧美老妇| 7777精品伊久久久大香线蕉| 色婷婷av一区二区三区浪潮| 亚洲人成电影在线观看影院| 亚洲制服丝袜av一区二区三区| 99精品全国免费观看视频| 亚洲第一无码精品立川理惠| 欧美性黑人极品hd另类| 国产成人高清亚洲一区妲妃|