在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Ras-related protein Rab-12 (RAB12)

  • 中文名稱:
    人RAB12重組蛋白
  • 貨號(hào):
    CSB-YP753710HU
  • 規(guī)格:
    ¥2208
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    RAB12
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Full Length
  • 來(lái)源:
    Yeast
  • 分子量:
    28.1 kDa
  • 表達(dá)區(qū)域:
    1-244aa
  • 氨基酸序列
    MDPGAALQRRAGGGGGLGAGSPALSGGQGRRRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREITRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDILRNELSNSILSLQPEPEIPPELPPPRPHVRCC
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    C-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy.
  • 基因功能參考文獻(xiàn):
    1. DENND3 is the exchange factor for the small GTPase Rab12 regulated through an intramolecular interaction PMID: 28249939
    2. a novel signaling pathway identified whereby starvation-induced activation of ULK leads to phosphorylation of endogenous DENND3, with subsequent activation of Rab12 and initiation of membrane trafficking events required for autophagy PMID: 25925668
    3. findings demonstrate the functional importance of Rab12 for retrograde toxin trafficking PMID: 24703428
  • 亞細(xì)胞定位:
    Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Lysosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane. Cytoplasmic vesicle, autophagosome.
  • 蛋白家族:
    Small GTPase superfamily, Rab family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 31332

    OMIM: 616448

    KEGG: hsa:201475

    STRING: 9606.ENSP00000331748

    UniGene: Hs.270074



主站蜘蛛池模板: 久久99精品久久久久久动态图 | 爆乳女仆高潮在线观看| 成人性生交大片免费看r老牛网站| 天堂网www天堂在线资源| 国产高跟黑色丝袜在线| 国产日韩av在线播放| 亚洲国产婷婷六月丁香 | 人妻熟妇乱又伦精品hd| 情侣黄网站免费看| 国产成人免费97在线观看| 亚洲爆乳成av人在线视菜奈实| 无码中文字幕av免费放dvd| 免费无码又爽又高潮视频| 十八岁污网站在线观看| 亚洲国产精品一区二区手机| 久久人人97超碰国产公开| 日本无码欧美一区精品久久| 亚洲图片自拍偷图区| 国产+成+人+亚洲欧洲自线| 国产ww久久久久久久久久| 综合色区亚洲熟妇另类| 性欧美俄罗斯极品| 久久好在线视频| 无码人妻精品一区二区三区9厂 | 少妇做爰又色又紧夜视频| 亚洲精品国产av现线| 亚洲国产av无码精品| 亚洲精品美女久久久久99| 蜜臀av色欲a片无码一区| 极品少妇小泬50pthepon| 高清无码午夜福利视频| 无码精品国产一区二区免费| 国产最大成人亚洲精品| 性猛交ⅹxxx富婆视频| 亚洲在av人极品无码| 成熟老妇女毛茸茸的做性| 中文字幕高清免费日韩视频在线| 亚洲精品无人区| 国产成人8x人网站视频在线观看| 337p日本欧洲亚洲大胆张筱雨| 乱亲女h秽乱长久久久|