在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human RNA polymerase-associated protein RTF1 homolog (RTF1)

  • 中文名稱:
    人RTF1重組蛋白
  • 貨號:
    CSB-YP821675HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人RTF1重組蛋白
  • 貨號:
    CSB-EP821675HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人RTF1重組蛋白
  • 貨號:
    CSB-EP821675HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人RTF1重組蛋白
  • 貨號:
    CSB-BP821675HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人RTF1重組蛋白
  • 貨號:
    CSB-MP821675HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    RTF1
  • Uniprot No.:
  • 別名:
    CDG1N; GTL 7; GTL7; KIAA0252; Ortholog of mouse gene trap locus 7; RNA polymerase associated protein RTF1 homolog; RNA polymerase-associated protein RTF1 homolog; RTF 1; RTF1; Rtf1 Paf1/RNA polymerase II complex component homolog; RTF1_HUMAN; rtf1L; YGL244W
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-710
  • 氨基酸序列
    MRGRLCVGRA AAAAAAVAVP LAGGQEGSPG GGRRGSRGTT MVKKRKGRVV IDSDTEDSGS DENLDQELLS LAKRKRSDSE EKEPPVSQPA ASSDSETSDS DDEWTFGSNK NKKKGKARKI EKKGTMKKQA NKTASSGSSD KDSSAESSAP EEGEVSDSDS NSSSSSSDSD SSSEDEEFHD GYGEDLMGDE EDRARLEQMT EKEREQELFN RIEKREVLKR RFEIKKKLKT AKKKEKKEKK KKQEEEQEKK KLTQIQESQV TSHNKERRSK RDEKLDKKSQ AMEELKAERE KRKNRTAELL AKKQPLKTSE VYSDDEEEEE DDKSSEKSDR SSRTSSSDEE EEKEEIPPKS QPVSLPEELN RVRLSRHKLE RWCHMPFFAK TVTGCFVRIG IGNHNSKPVY RVAEITGVVE TAKVYQLGGT RTNKGLQLRH GNDQRVFRLE FVSNQEFTES EFMKWKEAMF SAGMQLPTLD EINKKELSIK EALNYKFNDQ DIEEIVKEKE RFRKAPPNYA MKKTQLLKEK AMAEDLGDQD KAKQIQDQLN ELEERAEALD RQRTKNISAI SYINQRNREW NIVESEKALV AESHNMKNQQ MDPFTRRQCK PTIVSNSRDP AVQAAILAQL NAKYGSGVLP DAPKEMSKGQ GKDKDLNSKS ASDLSEDLFK VHDFDVKIDL QVPSSESKAL AITSKAPPAK DGAPRRSLNL EDYKKRRGLI
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both independently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3' end formation probably through association with cleavage and poly(A) factors. In case of infection by influenza A strain H3N2, PAF1C associates with viral NS1 protein, thereby regulating gene transcription. Binds single-stranded DNA. Required for maximal induction of heat-shock genes. Required for the trimethylation of histone H3 'Lys-4' (H3K4me3) on genes involved in stem cell pluripotency; this function is synergistic with CXXC1 indicative for an involvement of a SET1 complex.
  • 基因功能參考文獻:
    1. Human Rtf1 as a transcription elongation factor. PMID: 26217014
    2. Data indicate that the Plus3 domain of the Rtf1 subunit mediates Paf1C recruitment to genes by binding a repeating domain within the phosphorylated elongation factor Spt5. PMID: 24101474
  • 亞細胞定位:
    Nucleus, nucleoplasm.
  • 數據庫鏈接:

    HGNC: 28996

    OMIM: 611633

    KEGG: hsa:23168

    STRING: 9606.ENSP00000374280

    UniGene: Hs.511096



主站蜘蛛池模板: а天堂中文官网| 日韩不卡1卡2卡三卡网站| 欧美日产国产精品| 久久人妻内射无码一区三区| 国模小婕私拍鲜嫩玉门| 精品久久国产综合婷婷五月| 国产精品992tv在线观看| 越南毛茸茸的少妇| 亚洲中文字幕无码一久久区| 欧美韩中文精品有码视频在线| 久久精品国产久精国产爱| 一本久久知道综合久久| 山东熟女啪啪哦哦叫| 国产毛片毛多水多的特级毛片| 亚洲成av人片在线观看高清 | 亚洲国产精品18久久久久久| 国产成人精品午夜视频| 天天天天做夜夜夜做| 中文字幕色av一区二区三区 | 久久精品人妻少妇一区二区三区| 国产成人综合亚洲精品| 国产欧美国日产高清| 免费中文熟妇在线影片| 国产95在线 | 欧美| 亚洲国产成人精品无码区宅男| 久久无码人妻一区二区三区午夜 | 四虎永久在线精品免费网址| 国产区精品一区二区不卡中文| 国产9 9在线 | 欧洲| 日韩综合夜夜香内射| 婷婷网亚洲色偷偷男人的天堂| 免费午夜福利不卡片在线播放| 性做久久久久久免费观看| 午夜无码大尺度福利视频 | 性高湖久久久久久久久| 欧美v亚洲v日韩v最新在线| 欧美综合精品久久久久成人影院 | 欧美午夜理伦三级在线观看| 国产欧美日韩视频一区二区三区| 免费观看又污又黄的网站| 国产极品美女高潮抽搐免费网站|