在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human RNA-binding protein with multiple splicing (RBPMS)

In Stock
  • 中文名稱:
    人RBPMS重組蛋白
  • 貨號:
    CSB-EP821892HU
  • 規格:
    ¥1836
  • 圖片:
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP821892HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) RBPMS.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP821892HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) RBPMS.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    RBPMS
  • Uniprot No.:
  • 別名:
    FLJ32971; Heart and RRM expressed sequence; Hermes; RBP MS; RBP-MS; Rbpms; RBPMS_HUMAN; RNA binding protein gene with multiple splicing; RNA-binding protein with multiple splicing
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    28.8 kDa
  • 表達區域:
    1-196aa
  • 氨基酸序列
    MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGSLIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGTPNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYPASLHAQMRWLPPSEATSQGWKSRQFC
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.
  • 基因功能參考文獻:
    1. The possible involvement of the GC box 1 at position - 54 in transcriptional regulation of Rbpms was corroborated by EMSA, which showed formation of a DNA-protein complex in the presence of the oligonucleotide corresponding to this Sp1-binding site. PMID: 29423656
    2. Data indicate RNA Binding Protein with Multiple Splicing (RBPMS), Regulator of Chromosome Condensation and POZ Domain Containing Protein 1 (RCBTB1), and Zinc Finger protein 608 (ZNF608) as miR-21-3p target genes. PMID: 27166999
    3. Conserved binding of GCAC motifs by MEC-8, couch potato, and the RBPMS protein family has been reported. PMID: 28003515
    4. ERG is recruited to mRNAs via interaction with the RNA-binding protein RBPMS, and it promotes mRNA decay by binding CNOT2, a component of the CCR4-NOT deadenylation complex. PMID: 27273514
    5. observation of a strong in vivo erythropoietic effect for RBPMS but not for GTF2E2, supporting the statistical fine-mapping at this locus and demonstrating that RBPMS is a regulator of erythropoiesis PMID: 28017375
    6. Study indicates that the RNA binding increases the stability of RNA-recognition motif (RRM) in RBPMS domain, but residue mutations of RRM domain induce the fluctuation of complex systems through weakening of hydrogen bonds, conformational change or loss of binding affinity. PMID: 27592836
    7. RBPMS1 is a critical repressor of AP-1 signaling and RBPMS1 activation may be a useful strategy for cancer treatment. PMID: 25281386

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm. Cytoplasm, P-body.
  • 組織特異性:
    Ubiquitously expressed, at various levels depending on the isoform and the tissue.
  • 數據庫鏈接:

    HGNC: 19097

    OMIM: 601558

    KEGG: hsa:11030

    STRING: 9606.ENSP00000340176

    UniGene: Hs.334587



主站蜘蛛池模板: 人人妻人人澡人人爽人人精品| 少妇精品偷拍高潮少妇小说| 麻豆人妻无码性色av专区| 无码帝国www无码专区色综合| 国内揄拍国内精品少妇 | 亚洲日韩中文字幕在线不卡最新| 亚洲综合欧美制服丝袜| 日韩在线成年视频人网站观看| 豆国产95在线 | 亚洲| 欧美精品亚洲精品日韩传电影| 日日躁夜夜躁狠狠躁| 午夜福利啪啪无遮挡免费| 久久九九精品国产免费看小说| 早起邻居人妻奶罩太松av| 日本japanese丰满少妇| 亚洲欧美日韩国产成人| 午夜福利一区二区三区高清视频| 野花在线无码视频在线播放 | 亚洲一区在线观看尤物| 日本饥渴人妻欲求不满| 乱子轮熟睡1区| 毛片完整版的免费观看| 国产成人a在线观看视频| 久久久亚洲精品一区二区三区| 久久99国产亚洲高清观看首页| 午夜精品久久久内射近拍高清 | 久99久无码精品视频免费播放| 国产成人92精品午夜福利| 亚洲中国最大av网站| 人妻熟女一区二区三区app下载| 亚洲电影在线观看| 插我舔内射18免费视频| 欧美性猛交xxx嘿人猛交| 国产中的精品av一区二区| 99久久人人爽亚洲精品美女 | 精品久久久久久久无码| 酒店大战丝袜高跟鞋人妻| 伊人久久成综合久久影院| 国产 日韩 欧美 视频 制服| 夫妻免费无码v看片| 内射老妇bbwx0c0ck|