在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Pyrin and HIN domain-containing protein 1 (PYHIN1)

  • 中文名稱:
    人PYHIN1重組蛋白
  • 貨號:
    CSB-YP746957HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PYHIN1重組蛋白
  • 貨號:
    CSB-EP746957HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PYHIN1重組蛋白
  • 貨號:
    CSB-EP746957HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PYHIN1重組蛋白
  • 貨號:
    CSB-BP746957HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PYHIN1重組蛋白
  • 貨號:
    CSB-MP746957HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PYHIN1
  • Uniprot No.:
  • 別名:
    IFIX_HUMAN; Interferon-inducible protein X; Pyhin1; Pyrin and HIN domain-containing protein 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-492
  • 氨基酸序列
    MANNYKKIVL LKGLEVINDY HFRIVKSLLS NDLKLNPKMK EEYDKIQIAD LMEEKFPGDA GLGKLIEFFK EIPTLGDLAE TLKREKLKVA NKIESIPVKG IIPSKKTKQK EVYPATPACT PSNRLTAKGA EETLGPQKRK KPSEEETGTK RSKMSKEQTR PSCSAGASTS TAMGRSPPPQ TSSSAPPNTS STESLKPLAN RHATASKNIF REDPIIAMVL NATKVFKYES SENEQRRMFH ATVATQTQFF HVKVLNINLK RKFIKKRIII ISNYSKRNSL LEVNEASSVS EAGPDQTFEV PKDIIRRAKK IPKINILHKQ TSGYIVYGLF MLHTKIVNRK TTIYEIQDKT GSMAVVGKGE CHNIPCEKGD KLRLFCFRLR KRENMSKLMS EMHSFIQIQK NTNQRSHDSR SMALPQEQSQ HPKPSEASTT LPESHLKTPQ MPPTTPSSSS FTKKDETHPG AQSSPANFRI TSPTVAPPLS SDTSTNRHPA VP
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
  • 基因功能參考文獻:
    1. Study demonstrates that IFIX antiviral functions work in part via viral transcriptional suppression and that HSV-1 has acquired mechanisms to block its functions via proteasome-dependent degradation. PMID: 28077445
    2. a new member of the hematopoietic interferon (IFN)-inducible nuclear protein. Six different alternatively spliced forms are transcribed from the IFIX gene PMID: 15122330
    3. IFIX alpha1 isoform functions as a tumor suppressor by repressing HDM2 function PMID: 16479015
    4. IFIXalpha suppressed the invasion activity of MDA-MB-468 breast cancer cells, and its inhibitory effect was reversed by the knockdown of maspin PMID: 18247378
  • 亞細胞定位:
    [Isoform 1]: Nucleus, nucleoplasm.; [Isoform 3]: Nucleus, nucleoplasm.; [Isoform 5]: Nucleus. Nucleus speckle.
  • 蛋白家族:
    HIN-200 family
  • 組織特異性:
    Expressed in spleen, lymph node and peripheral blood leukocytes, and at lower levels in thymus, bone marrow and fetal liver. Down-regulated in breast tumors.
  • 數據庫鏈接:

    HGNC: 28894

    OMIM: 612677

    KEGG: hsa:149628

    STRING: 9606.ENSP00000357122

    UniGene: Hs.710248



主站蜘蛛池模板: 长腿校花无力呻吟娇喘| 日韩人妻无码免费视频一区二区三区 | 色天使久久综合给合久久97色| 精品无码专区毛片| 国产av无码久久精品| 国产亚洲精品久久久性色情软件 | 国产精品992tv在线观看| 中文字幕人妻色偷偷久久| 中文字幕av无码不卡| av狼友无码国产在线观看| 欧美老肥妇多毛xxxxx| 国色天香国产精品| 国产女人乱子对白av片| 试看120分钟做受小视频| 国产亚洲精品久久久久久打不开| 久久综合色_综合色88| 一本热久久sm色国产| 99久久国产热无码精品免费| 亚洲欧美日韩国产综合一区二区| 首页 国产 亚洲 丝袜图片区| 亚洲一区二区三区乱码在线欧洲| 国产乱人伦偷精品视频| 亚洲成av人在线播放无码| 色综合天天天天综合狠狠爱| aⅴ亚洲 日韩 色 图网站 播放| 国产精品熟女高潮视频| av天堂永久资源网亚洲高清| 乱人伦视频中文字幕| 日韩亚洲欧美精品综合| 无码人妻精品一区二区| 直接观看黄网站免费视频| 国产午夜鲁丝片av无码免费| 少妇的肉体在线观看| 欧美金妇欧美乱妇xxxx| 成年女人永久免费看片| 亚洲肥老太bbw中国熟女| 少妇真实被内射视频三四区| 欧美村妇激情内射| 狠狠色噜噜狠狠狠狠色综合网| 日韩欧美猛交xxxxx无码| 日本少妇肉体裸交xxx|