在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein transport protein Sec61 subunit beta (SEC61B), partial

  • 中文名稱:
    人SEC61B重組蛋白
  • 貨號:
    CSB-YP020958HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SEC61B重組蛋白
  • 貨號:
    CSB-EP020958HU1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SEC61B重組蛋白
  • 貨號:
    CSB-EP020958HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SEC61B重組蛋白
  • 貨號:
    CSB-BP020958HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SEC61B重組蛋白
  • 貨號:
    CSB-MP020958HU1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    SEC61B; Protein transport protein Sec61 subunit beta
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Component of a ribosome-associated ER translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER. Required for PKD1/Polycystin-1 biogenesis.
  • 基因功能參考文獻:
    1. used whole exome sequencing in a discovery cohort of 102 unrelated patients who were excluded for mutations in the 2 most common polycystic liver disease genes, PRKCSH and SEC63, to identify heterozygous loss-of-function mutations in 3 additional genes, ALG8, GANAB, and SEC61B. Similarly to PRKCSH and SEC63, these genes encode proteins that are integral to the protein biogenesis pathway in the endoplasmic reticulum. PMID: 28375157
    2. Sec61beta overexpression increased tight junction modulation rates, in conjunction with enhanced delivery of claudin-4 from and to plasma membranes. PMID: 24882410
    3. Sec61beta-KD cells also exhibited altered ATP7A cellular distribution. PMID: 22710939
    4. SEC61beta and its autoantibody as biomarkers for colorectal cancer PMID: 21255561
    5. Sec61beta function provides an alternative pathway for nuclear transport that can be utilized by membrane-embedded proteins such as full-length EGFR. PMID: 20937808
    6. This indicates that EGF receptors are trafficked from the endoplasmic reticulum to the nucleus by a novel pathway that involves the Sec61 translocon. PMID: 17215517

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族:
    SEC61-beta family
  • 數據庫鏈接:

    HGNC: 16993

    OMIM: 609214

    KEGG: hsa:10952

    STRING: 9606.ENSP00000223641

    UniGene: Hs.191887



主站蜘蛛池模板: 国模大尺度福利视频在线| 人与狗精品aa毛片| 美女粉嫩饱满的一线天mp4 | 日产a一a区二区www| 少妇粗大进出白浆嘿嘿视频| 久久综合色之久久综合| 午夜成人爽爽爽视频在线观看| 日韩国产成人无码av毛片蜜柚| 久久国产精品久久久久久| 国产精品ⅴ无码大片在线看| 亚洲成年网站青青草原| 中文字幕+乱码+中文字幕一区| 一本大道东京热无码| 中文字幕人成无码人妻| 无人区码一码二码三码区别新月| 在线不卡av片免费观看| 伴郎粗大的内捧猛烈进出视频观看 | 狠狠综合亚洲综合亚洲色| 国产精品白丝喷浆| 特级西西人体444www高清大胆| 天天弄天天模| 亚洲精品一品区二品区三区| 天堂亚洲国产中文在线| 精品国产亚洲一区二区三区| 亚洲熟妇色xxxxx欧美老妇| 亚洲成a人v欧美综合天堂下载| 色偷偷色噜噜狠狠网站年轻人| 男女做爰真人视频直播| 亚洲欧美综合中文| 亚洲精品午夜一区二区电影院 | 日本丰满护士videossexhd| 国产成人精品一区二区秒拍| 国产午夜亚洲精品区| 丰满的少妇邻居中文bd| 51国产偷自视频区视频| 亚洲午夜精品a片久久www慈禧| 亚洲中文字幕久久精品蜜桃| 中国少妇内射xxxhd免费| 97超级碰碰人妻中文字幕| 免费国产黄网在线观看| 欧美日韩国产综合新一区|