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Recombinant Human Protein strawberry notch homolog 2 (SBNO2), partial

  • 中文名稱:
    人SBNO2重組蛋白
  • 貨號:
    CSB-YP896873HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SBNO2重組蛋白
  • 貨號:
    CSB-EP896873HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SBNO2重組蛋白
  • 貨號:
    CSB-EP896873HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SBNO2重組蛋白
  • 貨號:
    CSB-BP896873HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SBNO2重組蛋白
  • 貨號:
    CSB-MP896873HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SBNO2
  • Uniprot No.:
  • 別名:
    SBNO2; KIAA0963Protein strawberry notch homolog 2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation. Involved in the transcriptional corepression of NF-kappaB in macrophages. Plays a role as a regulator in the proinflammatory cascade.
  • 基因功能參考文獻:
    1. The SBNO2 is component of the pathways that contribute to the downstream anti-inflammatory effects of IL-10. PMID: 18025162
  • 蛋白家族:
    SBNO family
  • 組織特異性:
    Detected in macrophages. IL10 regulates expression in a STAT3-dependent way.
  • 數據庫鏈接:

    HGNC: 29158

    OMIM: 615729

    KEGG: hsa:22904

    STRING: 9606.ENSP00000354733

    UniGene: Hs.408708



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