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  4. SBNO2 Antibody, Biotin conjugated

SBNO2 Antibody, Biotin conjugated

  • 中文名稱：
    SBNO2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA896873LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) SBNO2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    SBNO2
  • 別名：
    SBNO2 antibody; KIAA0963Protein strawberry notch homolog 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation. Involved in the transcriptional corepression of NF-kappaB in macrophages. Plays a role as a regulator in the proinflammatory cascade.
  • 基因功能參考文獻：
    1. The SBNO2 is component of the pathways that contribute to the downstream anti-inflammatory effects of IL-10. PMID: 18025162
  • 蛋白家族：
    SBNO family
  • 組織特異性：
    Detected in macrophages. IL10 regulates expression in a STAT3-dependent way.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29158

    OMIM: 615729

    KEGG: hsa:22904

    STRING: 9606.ENSP00000354733

    UniGene: Hs.408708



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