在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein phosphatase 1K, mitochondrial (PPM1K)

  • 中文名稱:
    人PPM1K重組蛋白
  • 貨號:
    CSB-YP822697HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PPM1K重組蛋白
  • 貨號:
    CSB-EP822697HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PPM1K重組蛋白
  • 貨號:
    CSB-EP822697HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PPM1K重組蛋白
  • 貨號:
    CSB-BP822697HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PPM1K重組蛋白
  • 貨號:
    CSB-MP822697HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PPM1K
  • Uniprot No.:
  • 別名:
    BDP; mitochondrial; MSUDMV; PP2C domain containing protein phosphatase 1K; PP2C domain-containing protein phosphatase 1K; PP2C kappa; PP2C like mitochondrial protein; PP2C type mitochondrial phosphoprotein phosphatase; PP2C-kappa; PP2C-like mitochondrial protein; PP2C-type mitochondrial phosphoprotein phosphatase; PP2Ckappa; PP2CM; PPM1K; PPM1K_HUMAN; Protein phosphatase 1K; Protein phosphatase 1K; mitochondrial; Protein phosphatase 2C isoform kappa; Protein phosphatase Mg2+/Mn2+ dependent 1K; PTMP; UG0882E07
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    30-372
  • 氨基酸序列
    D DRRVTPTCHS STSEPRCSRF DPDGSGSPAT WDNFGIWDNR IDEPILLPPS IKYGKPIPKI SLENVGCASQ IGKRKENEDR FDFAQLTDEV LYFAVYDGHG GPAAADFCHT HMEKCIMDLL PKEKNLETLL TLAFLEIDKA FSSHARLSAD ATLLTSGTTA TVALLRDGIE LVVASVGDSR AILCRKGKPM KLTIDHTPER KDEKERIKKC GGFVAWNSLG QPHVNGRLAM TRSIGDLDLK TSGVIAEPET KRIKLHHADD SFLVLTTDGI NFMVNSQEIC DFVNQCHDPN EAAHAVTEQA IQYGTEDNST AVVVPFGAWG KYKNSEINFS FSRSFASSGR WA
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development.
  • 基因功能參考文獻:
    1. Branched chain amino acids related genetic variant rs1440581 was associated with an increased risk of incident T2 Diabetes in a Chinese population. This variant might modify effect of weight gain on development in Insulin resistance. PMID: 29855804
    2. PPM1K rs1440581 may affect changes in glucose metabolism during weight loss, and this effect is dependent on dietary fat and carbohydrate intakes. PMID: 28768654
    3. miR-204 and miR-211 directly repress PPM1K expression via 3'UTR. PMID: 26592513
    4. Overweight people with the C allele of the branched-chain amino acid/aromatic amino acid ratio-associated variant rs1440581 may benefit less in weight loss and improved insulin sensitivity than those without it on a energy-restricted high-fat diet. PMID: 23446828
    5. The 2.4 A PP2Cm structure reveals a central beta-sandwich with two bound metal ions in the active-site cleft. PMID: 22291014
    6. A novel member of human protein phosphatase 2C gene family named PP2Ckappa was isolated from a human fetal brain cDNA library. PMID: 16685424
    7. The cloned phosphatase has a mitochondrial leader sequence and its amino acid sequence places it in the PP2C family like two known mitochondrial phosphatases. PMID: 17336929

    顯示更多

    收起更多

  • 相關疾病:
    Maple syrup urine disease, mild variant (MSUDMV)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    PP2C family
  • 數據庫鏈接:

    HGNC: 25415

    OMIM: 611065

    KEGG: hsa:152926

    STRING: 9606.ENSP00000295908

    UniGene: Hs.43744



主站蜘蛛池模板: 国产精品无码一区二区三区免费 | 日本中文一区二区三区亚洲| 国模丽丽啪啪一区二区| 婷婷五月深深久久精品| 亚洲 综合 欧美 动漫 丝袜| 思思久久精品一本到99热| 202丰满熟女妇大| 东京热一区二区三区无码视频| 中文字幕日韩精品亚洲一区 | 偷自拍亚洲视频在线观看99| 97人妻熟女成人免费视频色戒 | 玩弄放荡人妻一区二区三区| 亚洲色无码专线精品观看| 亚洲精品无码永久中文字幕| 亚洲精品久久久久中文字幕| 国色天香成人网| 狠狠久久久久综合成人影院| 国产高清在线精品一区二区三区| 久久婷婷国产综合精品| 精品无人区卡一卡二卡三乱码| 夜夜澡人摸人人添人人看 | 亚洲成在人线在线播放无码vr| 小嫩妇好紧好爽18禁视频| 日本丰满熟妇videos| 2020每日更新国产精品视频| 国产成人无码av大片大片在线观看 | 国产精品51麻豆cm传媒| 亚洲性av免费| 亚洲制服丝袜自拍中文字幕| 熟妇人妻无码中文字幕| 无码一区二区三区av免费| 久久综合精品国产一区二区三区无码| 很黄很色60分钟在线观看| 69精品丰满人妻无码视频a片| 中国女人大白屁股ass| 扒开双腿猛进入喷水高潮视频| 亚洲精品久久| 国产成人无码免费视频在线 | 亚洲最大无码中文字幕网站| √天堂8资源中文在线| 精品久久久久久久久中文字幕|