在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein orai-2 (ORAI2), partial

  • 中文名稱:
    人ORAI2重組蛋白
  • 貨號:
    CSB-YP853504HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人ORAI2重組蛋白
  • 貨號:
    CSB-EP853504HU1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人ORAI2重組蛋白
  • 貨號:
    CSB-EP853504HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人ORAI2重組蛋白
  • 貨號:
    CSB-BP853504HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人ORAI2重組蛋白
  • 貨號:
    CSB-MP853504HU1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    ORAI2; C7orf19; CBCIP2; TMEM142B; PP1729; Protein orai-2; CAP-binding protein complex-interacting protein 2; Transmembrane protein 142B
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1.
  • 基因功能參考文獻:
    1. ORAI1-3, are preferentially expressed in proximal tubular epithelial cells and downregulated in patients with diabetic nephropathy. PMID: 29203863
    2. findings provide evidence for a role for Orai1 and Orai2, in SOCE and migration in the human HL60 promyeloblastic cell line PMID: 27865925
    3. results identified the ORAI-NOX2 feedback loop as a determinant of monocyte immune responses. PMID: 26956485
    4. Orai1, Orai2 and STIM1 form functional Ca(2+) release-activated Ca(2+) channels in OUMS-27 cells (chondrocytes) and that these complexes are responsible for sustained Ca(2+) entry in response to agonist stimulation. PMID: 25769459
    5. Orai1 but not Orai2 plays a major role in the influx of extracellular Ca2+ into and mediator release from HLMCs following their activation PMID: 24040356
    6. Orai1 and Orai2 operate in a STIM-dependent manner, Orai3 does not interact with STIM isoforms upon calcium store depletion in platelets. PMID: 22640869
    7. With these data we show a new Ca(2)(+) entry pathway linked to the Ca(2)(+)/inositolphosphate second-messenger system in RPE cells which help to further understand regulatory pathways of agonists. PMID: 20607548
    8. Results suggest that Orai1, -2, and -3 channels are similarly inhibited by extracellular calcium, indicating similar affinities for Ca(2+) within the selectivity filter. PMID: 17452328
    9. The effects of 2-aminoethoxydiphenyl borate on orai1, orai2, orai3 metabolism in HEK293 cells with and without STIM1 are reported. PMID: 18403424
    10. analysis of activation of Orai1-3 channels by a STIM1 coiled-coil mutant PMID: 19506081
    11. Data show that the fast Ca(2+)-dependent inactivation is mediated by three conserved glutamates in the C termini (CT) of Orai2 and Orai3, which show prominent fast Ca(2+)-dependent inactivation compared with Orai1. PMID: 19706554

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Orai family
  • 數據庫鏈接:

    HGNC: 21667

    OMIM: 610929

    KEGG: hsa:80228

    STRING: 9606.ENSP00000348752

    UniGene: Hs.363308



主站蜘蛛池模板: 日产精品一区2区卡四卡二卡| 亚洲精品永久在线观看| 国产av综合影院| 久久综合97丁香色香蕉| 美女黄网站18禁免费看| 色婷婷综合久色aⅴ五区最新| 欧美最猛性xxxxx免费| 亚洲一区二区三区在线观看网站| 少妇人妻中文字幕污| 欧美日产国产精品| 欧美 国产 综合 欧美 视频| 亚洲第一无码专区天堂| 人妻系列无码一区二区三区| 免费观看全黄做爰大片国产| 国产sm主人调教女m视频| 日本无码人妻精品一区二区蜜桃| 日韩精品无码去免费专区| 亚洲成a人v欧美综合天堂麻豆| 久久久无码人妻精品一区| 日本欧美一区二区免费视频| 国产午夜片无码区在线观看| 福利一区二区三区视频在线观看| 亚洲一卡一卡二新区无人区 | 少妇被躁爽到高潮无码文| 色综合久久无码中文字幕| 国产 高潮 抽搐 正在播放| 7777奇米成人狠狠成人影视| 凹凸在线无码免费视频| 另类 专区 欧美 制服| 久热这里只有精品99在线观看| 男ji大巴进入女人的直播| 日韩va中文字幕无码电影| 好男人日本社区www| 中文字幕制服丝袜第57页| 中文亚洲欧美日韩无线码| 在线中文新版最新版在线| 中文字幕 欧美精品 第1页| 免费观看黄网站| 亚洲精品一区二区三区新线路| 国产亚洲熟妇综合视频| 漂亮人妻被黑人久久精品|