在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein SERAC1 (SERAC1), partial

  • 中文名稱:
    人SERAC1重組蛋白
  • 貨號:
    CSB-YP853443HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SERAC1重組蛋白
  • 貨號:
    CSB-EP853443HU1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SERAC1重組蛋白
  • 貨號:
    CSB-EP853443HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SERAC1重組蛋白
  • 貨號:
    CSB-BP853443HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SERAC1重組蛋白
  • 貨號:
    CSB-MP853443HU1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SERAC1
  • Uniprot No.:
  • 別名:
    SERAC1; Protein SERAC1; Serine active site-containing protein 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays an important role in the phosphatidylglycerol remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking. May catalyze the remodeling of phosphatidylglycerol and be involved in the transacylation-acylation reaction to produce phosphatidylglycerol-36:1. May be involved in bis(monoacylglycerol)phosphate biosynthetic pathway.
  • 基因功能參考文獻:
    1. Two novel SERAC1 mutations were identified in two cases of dystonia, 3-methylglutaconic aciduria and intellectual disability syndrome. PMID: 28778788
    2. mutations in the phosphatidylglycerol remodelling enzyme SERAC1 can cause juvenile-onset complicated hereditary spastic paraplegia (cHSP) clusters PMID: 28916646
    3. Several different SERAC1 variants were identified from individuals with Deafness-Dystonia syndrome. PMID: 29205472
    4. Here we report two new Turkish sibling patients affected with MEGDEL syndrome due to SERAC1 gene mutation. PMID: 27186703
    5. Infantile mitochondrial hepatopathy is a cardinal feature of MEGDEL syndrome (3-methylglutaconic aciduria type IV with sensorineural deafness, encephalopathy and Leigh-like syndrome) caused by novel mutations in SERAC1. PMID: 23918762
    6. During the course of this project a parallel study identified mutations in SERAC1 as the genetic cause of the disease in 15 patients with MEGDEL syndrome, which was compatible with the clinical and biochemical phenotypes of the patient described here. PMID: 23707711
    7. Data identify SERAC1 as a key player in the phosphatidylglycerol remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking. PMID: 22683713

    顯示更多

    收起更多

  • 相關疾病:
    3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (MEGDEL)
  • 亞細胞定位:
    Membrane; Single-pass membrane protein. Endoplasmic reticulum. Mitochondrion. Note=Localizes at the endoplasmic reticulum and at the endoplasmic reticulum-mitochondria interface.
  • 蛋白家族:
    SERAC1 family
  • 組織特異性:
    Widely expressed, with predominant expression in fetal skeletal muscle and adult brain. In the brain, highest levels are found in the frontal and occipital cortices, cerebellum and hippocampus.
  • 數據庫鏈接:

    HGNC: 21061

    OMIM: 614725

    KEGG: hsa:84947

    STRING: 9606.ENSP00000356071

    UniGene: Hs.154706



主站蜘蛛池模板: 免费无码黄十八禁网站在线观看 | 国产精品亚洲片在线观看不卡| 亚洲国产精品无码久久久动漫| 蜜臀av片在线观看| 76少妇精品导航| 国产熟睡乱子伦午夜视频| 丝袜自慰一区二区三区| 国产成人精品视频国产| 午夜福利啪啪片| 天天弄天天模| 免费人成网站在线观看欧美| 亚洲国产精品无码av| 午夜免费男女aaaa片| 国产无套乱子伦精彩是白视频| 国产成人综合在线女婷五月99播放 | 久久久无码人妻精品无码| 2020国产亚洲美女精品久久久| 狠狠色丁香久久综合| 久久久久无码国产精品一区| 四川老熟女下面又黑又肥| 韩国无码色视频在线观看| 中国免费看的片| 国内精品久久久久久中文字幕| 妖精色av无码国产在线看| 无码av喷白浆在线播放| 人妻夜夜添夜夜无码av| 少妇性l交大片毛多| 成人午夜福利院在线观看| 国产乱人伦真实精品视频| 老熟妇仑乱视频一区二区| 亚洲欧洲日产国码中文字幕| 亚洲一区二区三区自拍天堂| 国产精品妇女一二三区| 人人妻一区二区三区| 秋霞国产精品一区二区| 内射精品无码中文字幕| 久久天天躁狠狠躁夜夜av| 国产粉嫩嫩00在线正在播放| 少妇被多人c夜夜爽爽| 女人爽到高潮免费视频大全| 日本一区二区a√成人片|