在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein PTHB1 (BBS9), partial

  • 中文名稱:
    Recombinant Human Protein PTHB1(BBS9) ,partial
  • 貨號:
    CSB-YP659641HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Protein PTHB1(BBS9) ,partial
  • 貨號:
    CSB-EP659641HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Protein PTHB1(BBS9) ,partial
  • 貨號:
    CSB-EP659641HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Protein PTHB1(BBS9) ,partial
  • 貨號:
    CSB-BP659641HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Protein PTHB1(BBS9) ,partial
  • 貨號:
    CSB-MP659641HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    BBS9
  • Uniprot No.:
  • 別名:
    B1; Bardet Biedl syndrome 9; Bardet-Biedl syndrome 9 protein; bbs9; C18; D1; MGC118917; OTTHUMP00000158833; OTTHUMP00000202918; OTTHUMP00000202919; OTTHUMP00000202920; Parathyroid hormone-responsive B1 gene protein; Protein PTHB1; PTH-responsive osteosarcoma B1 protein; PTHB1; PTHB1_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.
  • 基因功能參考文獻:
    1. Our results provide evidence for new loci influencing abdominal visceral (BBS9, ADCY8, KCNK9) and subcutaneous (MLLT10/DNAJC1/EBLN1) fat, and confirmed a locus (THNSL2) previously reported to be associated with abdominal fat in women PMID: 26480920
    2. BBS9/PTHB1 gene mutations have been shown to be associated with Bardet Biedl syndrome and to the best of our knowledge this study reports the first Pakistani family linked to the BBS9 gene. PMID: 26846096
    3. BBS9 has four folded domains, based on structure prediction; the N-terminal domain is a beta-propeller. PMID: 26085087
    4. we report here, for the first time, in Indian population, a novel, different profile of mutations in BBS genes (BBS3, BBS9, BBS10 and BBS2) compared to worldwide (BBS1 and 10) reports. PMID: 24400638
    5. The endoplasmic reticulum membrane J protein C18 executes a distinct role in promoting simian virus 40 membrane penetration. PMID: 25631089
    6. Robust associations with nonsyndromic sagittal craniosynostosis were found in a 120-kb region downstream of BMP2 flanked by rs1884302 and rs6140226 and within a 167-kb region of BBS9 between rs10262453 and rs17724206. PMID: 23160099
    7. Human BBS9 mRNA rescues bbs9 knockdown phenotype in the zebrafish. PMID: 22479622
    8. gene is interrupted by a t(1;7)(q42;p15) breakpoint associated with Wilms' tumour; new alternately spliced isoforms were found in a wide range of adult and foetal tissues PMID: 12618763
    9. Comparative genomics and gene expression analysis identifies PHTB1 protein as BBS9, a new Bardet-Biedl syndrome gene. PMID: 16380913
    10. PTHB1 is strongly associated with POF, and ht1 confers susceptibility to POF PMID: 18349106

    顯示更多

    收起更多

  • 相關疾病:
    Bardet-Biedl syndrome 9 (BBS9)
  • 亞細胞定位:
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
  • 組織特異性:
    Widely expressed. Expressed in adult heart, skeletal muscle, lung, liver, kidney, placenta and brain, and in fetal kidney, lung, liver and brain.
  • 數據庫鏈接:

    HGNC: 30000

    OMIM: 607968

    KEGG: hsa:27241

    STRING: 9606.ENSP00000242067

    UniGene: Hs.372360



主站蜘蛛池模板: 最近中文字幕免费mv在线视频| 少妇高潮惨叫久久久久久| 超碰色偷偷男人的天堂| 亚洲高清专区日韩精品| 亚洲国产精品一区二区制服| 扒开女人内裤猛进猛出免费视频| 少妇无码一区二区三区| 久久久橹橹橹久久久久高清| 伊人狼人大焦香久久网| 国产天堂亚洲国产碰碰| 无码h片在线观看网站| 国产亚洲精品福利在线无卡一| 国产成人亚洲高清一区| 欧美亚洲另类自拍丝袜| 人人爽人人片人人片av| 成人免费直播| 亚洲 欧美 日产 综合 在线| 亚洲色国产欧美日韩| 人妻 色综合网站| 乱人伦xxxx国语对白| 亚洲国产成人精品无码区花野真一| 香蕉视频在线精品视频| 国产精品99久久免费黑人人妻| 久久久久蜜桃精品成人片| 欧美日韩国产专区一区二区 | 国产一区二区三区在线观看| 最近在线更新8中文字幕免费| 最近中文字幕免费mv在线视频| 亚洲六月丁香六月婷婷| 国产黄大片在线观看画质优化| 色婷婷六月亚洲婷婷丁香| 国产偷国产偷亚洲清高网站| 野花社区在线观看视频| 成人网站免费观看入口| 玩弄丰满熟妇xxxxx性60| 亚洲精品成人av在线| 99久久人妻无码精品系列| 色综合天天综合高清网国产在线| 成人福利国产精品视频| 大乳丰满人妻中文字幕日本| 久久夜色撩人精品国产小说|