在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Protein IWS1 homolog (IWS1), partial

Recombinant Human Protein IWS1 homolog (IWS1), partial

  • 中文名稱：
    人IWS1重組蛋白
  • 貨號(hào)：
    CSB-YP822304HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    人IWS1重組蛋白
  • 貨號(hào)：
    CSB-EP822304HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人IWS1重組蛋白
  • 貨號(hào)：
    CSB-BP822304HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人IWS1重組蛋白
  • 貨號(hào)：
    CSB-MP822304HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    IWS1
  • Uniprot No.：
  • 別名：
    DKFZp761G0123; FLJ10006; FLJ14655; FLJ32319; Interacts with Spt6; iws1; IWS1 homolog; IWS1-like protein; IWS1_HUMAN; IWS1L; MGC126375; MGC126376; OTTHUMP00000162262; Protein IWS1 homolog
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.
  • 基因功能參考文獻(xiàn)：
    1. Altogether, these results indicate that a complex containing LEDGF/p75, Iws1, and Spt6 participates in regulating postintegration steps of HIV latency. PMID: 25590759
    2. IWS1, an RNA processing regulator, is phosphorylated by Akt3 and Akt1 at Ser720/Thr721 in lung cancer PMID: 24462114
    3. Here we report that the human homolog of Iws1, hIws1, physically interacts with protein arginine methyltransferases PRMT5 which methylates elongation factor Spt5 and regulates its interaction with RNA polymerase II. PMID: 17184735
    4. binding of Spt6 to Ser2-P RNAPII provides a cotranscriptional mechanism to recruit Iws1, REF1/Aly, and associated mRNA processing, surveillance, and export factors to responsive genes. PMID: 17234882
    5. recombinant Spt6 binds selectively to a stretch of uninterrupted consensus repeats located in the N-terminal half of the CTD and recruits Iws1 PMID: 19141475

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    IWS1 family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 25467

    KEGG: hsa:55677

    STRING: 9606.ENSP00000295321

    UniGene: Hs.469879



主站蜘蛛池模板： 少妇大叫太大太爽受不了| 女人的天堂a国产在线观看| 久久人人97超碰a片精品| 欧美最猛黑人xxxxx猛交| 乱熟女高潮一区二区在线| 亚洲中文字幕久在线| 亚洲精品卡一卡三卡四卡乱码| 亚洲中文字幕无码久久2018| 中出内射颜射骚妇| 无码区日韩特区永久免费系列| 成人做爰视频www网站| 亚洲国产精品福利片在线观看| 老太婆性杂交欧美肥老太| 亚洲国产精品无码久久一线| 久久久女人与动物群交毛片| 特大黑人娇小亚洲女| 国产97色在线 | 免| 中文字幕无码日韩专区| 久久久肥妇熟女ⅹxxx毛片| 日本特黄特色aaa大片免费| 色五月五月丁香亚洲综合网| 成人免费午夜无码视频在线播放| 97夜夜澡人人爽人人模人人喊| 精品一区二区三区无码免费直播| 毛片tv网站无套内射tv网站| 国产av久久久久精东av| 精品人无码一区二区三区| 久久亚洲私人国产精品| 国产无套护士在线观看| 色欲aⅴ 无码| 久久久久成人精品无码| 亚洲一卡2卡3卡4卡 精品| 69风韵老熟女口爆吞精| 男人和女人做爽爽视频 | 欧美性猛交xxxx黑人猛交| 人人妻人人澡人人爽人人精品浪潮 | 在线视频国产网址你懂的| 免费人成视频19674不收费| 国产精品久久久久久影视| 中文字幕无码专区人妻系列| 亚洲综合伊人久久大杳蕉|