在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Probable methyltransferase BCDIN3D (BCDIN3D)

  • 中文名稱:
    Recombinant Human Probable methyltransferase BCDIN3D(BCDIN3D)
  • 貨號:
    CSB-YP767206HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Probable methyltransferase BCDIN3D(BCDIN3D)
  • 貨號:
    CSB-EP767206HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Probable methyltransferase BCDIN3D(BCDIN3D)
  • 貨號:
    CSB-EP767206HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Probable methyltransferase BCDIN3D(BCDIN3D)
  • 貨號:
    CSB-BP767206HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Probable methyltransferase BCDIN3D(BCDIN3D)
  • 貨號:
    CSB-MP767206HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    BCDIN3D
  • Uniprot No.:
  • 別名:
    BCDIN3 domain containing; BCDIN3 domain-containing protein; BCDIN3D; BN3D2_HUMAN; Probable methyltransferase BCDIN3D
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-292
  • 氨基酸序列
    MAVPTELDGG SVKETAAEEE SRVLAPGAAP FGNFPHYSRF HPPEQRLRLL PPELLRQLFP ESPENGPILG LDVGCNSGDL SVALYKHFLS LPDGETCSDA SREFRLLCCD IDPVLVKRAE KECPFPDALT FITLDFMNQR TRKVLLSSFL SQFGRSVFDI GFCMSITMWI HLNHGDHGLW EFLAHLSSLC HYLLVEPQPW KCYRAAARRL RKLGLHDFDH FHSLAIRGDM PNQIVQILTQ DHGMELICCF GNTSWDRSLL LFRAKQTIET HPIPESLIEK GKEKNRLSFQ KQ
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA(His)), acting as a capping enzyme by protecting tRNA(His) from cleavage by DICER1. Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Was also reported to mediate dimethylation of pre-miR-145; however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.
  • 基因功能參考文獻:
    1. BCDIN3D might serve as an important prognostic factor for triple-negative breast cancer PMID: 27259993
    2. BCDIN3D acts as a cytoplasmic tRNAHis-specific 5-methylphosphate capping enzyme. PMID: 28119416
    3. Human BCDIN3D monomethylates the 5'-monophosphate of cytoplasmic tRNAHis in vitro. In BCDN3D-knockout cells, established byCRISPR/Cas9 editing, the methyl moiety at the 5'-monophosphate of cytoplasmic tRNAHis is lost, and the exogenous expression of BCDIN3D in the knockout cells restores the modification in cytoplasmic tRNAHis. PMID: 28119416
    4. BCDIN3D depletion leads to lower pre-miR-145 and concomitantly increased mature miR-145 levels in breast cancer cells, which suppresses their tumorigenic phenotypes. PMID: 23063121
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Methyltransferase superfamily
  • 數據庫鏈接:

    HGNC: 27050

    KEGG: hsa:144233

    STRING: 9606.ENSP00000335201

    UniGene: Hs.142736



主站蜘蛛池模板: 国产精品爽爽久久久久久| 无码国产精成人午夜视频| 亚洲欧美日韩国产国产a| 无码人妻一区二区三区在线| 久久久久99精品成人片三人毛片 | 日韩精品极品视频在线观看免费| 国产精品无码专区久久久| 人人爽天天碰狠狠添| 人妻体验按摩到忍不住哀求继续 | 亚洲成a∨人片在无码2023| 日韩无套内射高潮| 亚洲男女一区二区三区 | 国产午夜无码片在线观看网站| 日韩一区精品视频一区二区| 亚洲字幕av一区二区三区四区| 丝袜无码一区二区三区| av综合网男人的天堂| 一本久久精品一区二区| 一边添奶一边添p好爽视频| 秋霞人妻无码中文字幕| 国内精品久久久久电影院| 国产又粗又硬又大爽黄老大爷视频 | 亚洲精品无码少妇30p| 一本大道东京热无码一区| 亚洲爆乳www无码专区| 久久三级中文欧大战字幕| 精品国产天堂综合一区在线| 亚洲视频在线观看| 亚洲精品国产精品制服丝袜| 女人爽到高潮视频免费直播 | 人与禽交videos欧美| 中国女人大白屁股ass| 女人摸下面自熨视频在线播放 | 国产亚洲精品久久久美女18黄| a毛片免费全部播放| 国产女人18毛片水真多| 久久久久无码中| 日本伦奷在线播放| 亚洲精品久久久狠狠爱小说| 无码少妇a片一区二区三区| 欧美精品黑人粗大|