在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Prion-like protein doppel (PRND)

  • 中文名稱:
  • 貨號(hào):
    CSB-YP890741HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
  • 貨號(hào):
    CSB-EP890741HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
  • 貨號(hào):
    CSB-EP890741HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
  • 貨號(hào):
    CSB-BP890741HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
  • 貨號(hào):
    CSB-MP890741HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Prion-like protein doppel; PrPLP; Prion protein 2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    26-152aa
  • 氨基酸序列
    TRGIKHRIKWNRKALPSTAQITEAQVAENRPGAFIKQGRKLDIDFGAEGNRYYEANYWQFPDGIHYNGCSEANVTKEAFVTGCINATQAANQGEFQKPDNKLHQQVLWRLVQELCSLKHCEFWLERG
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Required for normal acrosome reaction and for normal male fertility. Can bind Cu(2+).
  • 基因功能參考文獻(xiàn):
    1. results demonstrate that blocking doppel can control VEGF signaling in TECs and selectively inhibit tumor angiogenesis. PMID: 26950422
    2. The association between the APOE, CYP46, PRNP and PRND genes and the profile of neuropsychiatric symptoms in Polish subjects with Alzheimer's disease and mild cognitive impairment, was evaluated. PMID: 22453181
    3. in astrocytomas, Dpl undergoes different molecular processes that might constitute additional helpful tools to characterize the glial tumor progression PMID: 20981146
    4. Cytotoxicity induced by the expression of Dpl and truncated PrP in neural derived cells are closely related with the apoptosis process. PMID: 19728151
    5. expression pattern and biochemical characteristics in human tissues and in Chinese hamster ovary cells transfected with wild-type or variant human Dpl gene constructs PMID: 12200435
    6. Doppel expression is not modified in the brains of patients with Creutzfeldt-Jakob disease. PMID: 12586339
    7. human Doppel fails to interact with itself; Dpl and PrP are not related or are only marginally related with respect to their ligand binding behaviour PMID: 15158907
    8. results demonstrate that Doppel and PrPc co-patch extensively at the plasma membrane PMID: 15203115
    9. Doppel interacts with the full-length laminin receptor precursor protein PMID: 15246873
    10. Doppel is expressed early during ontogenesis, and is found in both germ cells and Sertoli cells. Doppel may play a physiological role in acrosome biogenesis. PMID: 16421231
    11. Extensive differences in PRND gene expression were also found within each grade of malignancy, suggesting that PRND mRNA quantitation might be useful to distinguish astrocytoma subtypes. PMID: 17390034
    12. Study provides the foundation for further study of Dpl biological functions in vitro and in vivo. PMID: 17894227
    13. Results might suggest a potential and functional role for Dpl in tumor cells migratory and morphological behaviours and address to future gene-targeted therapeutic interventions. PMID: 18936526
    14. results suggested that the function of Dpl is antagonistic to PrP rather than synergistic PMID: 19129949

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族:
    Prion family
  • 組織特異性:
    Expressed in testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid (at protein level).
  • 數(shù)據(jù)庫鏈接:

    HGNC: 15748

    OMIM: 604263

    KEGG: hsa:23627

    STRING: 9606.ENSP00000306900

    UniGene: Hs.406696



主站蜘蛛池模板: 高中生自慰www网站| 88久久精品无码一区二区毛片| 人妻免费一区二区三区最新| 9re热国产这里只有精品| 亚洲精品成人网线在线播放va | 中国熟妇牲交视频| 国产开嫩苞实拍在线播放视频| 日本无卡码高清免费v| 国产在热线精品视频| 成人免费视频一区二区三区| 日韩精品人妻系列无码专区免费| 国产熟女精品视频大全| 中国少妇初尝黑人巨高清| 人妻三级日本三级日本三级极| 大肉大捧一进一出好爽视频mba| 精品国产一区二区三区四区阿崩| 丰满多毛的大隂户毛茸茸| 久久中文字幕无码a片不卡古代| 56pao国产成视频永久| 国产电影一区二区三区| 精品国产三级在线观看| 色综合天天综合网中文| 国产精品嫩草99av在线| 国产欧美日韩精品丝袜高跟鞋| 四虎影视在线影院在线观看免费视频| 丰满少妇被猛烈进入高清播放| 成在人线av无码免观看麻豆| 中国凸偷窥xxxx自由视频| 国产又a又黄又潮娇喘视频| 精品国产乱码久久久久久郑州公司 | 亚洲欧洲av无码专区| 午夜内射中出视频| 亚洲精品乱码久久久久久按摩 | 国产线观看免费观看| 亚洲日韩中文字幕在线不卡最新| 国产精品久久久久久亚洲色| 天天综合网网欲色| 九九热线有精品视频| 人人妻人人澡人人爽欧美精品| 精品乱人伦一区二区三区| 国产精品成人免费一区久久羞羞 |