在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Polymerase delta-interacting protein 3 (POLDIP3)

Recombinant Human Polymerase delta-interacting protein 3 (POLDIP3)

  • 中文名稱：
    人POLDIP3重組蛋白
  • 貨號：
    CSB-YP871610HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人POLDIP3重組蛋白
  • 貨號：
    CSB-EP871610HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人POLDIP3重組蛋白
  • 貨號：
    CSB-EP871610HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人POLDIP3重組蛋白
  • 貨號：
    CSB-BP871610HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人POLDIP3重組蛋白
  • 貨號：
    CSB-MP871610HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    POLDIP3
  • Uniprot No.：
  • 別名：
    46 kDa DNA polymerase delta interaction protein; DNA polymerase delta interacting protein 3; KIAA1649; P46; PDIP3_HUMAN; PDIP46; POLDIP3; Polymerase (DNA-directed), delta interacting protein 3; Polymerase delta interacting protein 46; Polymerase delta-interacting protein 3; RNA-binding protein P46 ; S6K1 Aly/REF-like target; SKAR
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    2-421
  • 氨基酸序列
    ADISLDELI RKRGAAAKGR LNARPGVGGV RSRVGIQQGL LSQSTRTATF QQRFDARQKI GLSDARLKLG VKDAREKLLQ KDARFRIKGK VQDAREMLNS RKQQTTVPQK PRQVADAREK ISLKRSSPAA FINPPIGTVT PALKLTKTIQ VPQQKAMAPL HPHPAGMRIN VVNNHQAKQN LYDLDEDDDG IASVPTKQMK FAASGGFLHH MAGLSSSKLS MSKALPLTKV VQNDAYTAPA LPSSIRTKAL TNMSRTLVNK EEPPKELPAA EPVLSPLEGT KMTVNNLHPR VTEEDIVELF CVCGALKRAR LVHPGVAEVV FVKKDDAITA YKKYNNRCLD GQPMKCNLHM NGNVITSDQP ILLRLSDSPS MKKESELPRR VNSASSSNPP AEVDPDTILK ALFKSSGASV TTQPTEFKIK L
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex.
  • 基因功能參考文獻(xiàn)：
    1. Altered expression of PDIP46 or its mutation may affect Pol delta functions in vivo, and thereby be a nexus for altered genomic stability. PMID: 26819372
    2. hnRNP-U inhibits TDP-43-mediated alterations in splicing of POLDIP3 mRNA. PMID: 25378556
    3. PDIP3 and ZC11A associate with the human TREX complex in an ATP-dependent manner and function in mRNA export. PMID: 22928037
    4. these findings establish critical and essential roles for SKAR in the regulation of mRNA translation of IFN-sensitive genes and induction of IFN-alpha biological responses. PMID: 25049393
    5. Alteration of POLDIP3 splicing associated with loss of function of TDP-43 in tissues affected with amyotrophic lateral sclerosis (ALS) . PMID: 22900096
    6. SKAR is a specific target of S6K1 and regulates cell growth. PMID: 15341740
    7. This study showed that PDIP46 aka SKAR, a protein possessing one RNA recognition motif (RRM) and being a protein partner of both the p50 subunit of DNA polymerase delta and p70 ribosomal protein S6 kinase 1 (S6K1). PMID: 16984396
    8. SKAR-mediated recruitment of activated S6K1 to newly processed mRNPs serves as a conduit between mTOR checkpoint signaling and the pioneer round of translation when cells exist in conditions supportive of protein synthesis. PMID: 18423201

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 23782

    OMIM: 611520

    KEGG: hsa:84271

    STRING: 9606.ENSP00000252115

    UniGene: Hs.505802



主站蜘蛛池模板： 亚洲欧美日韩综合一区| 在线观看无码av网站永久免费| av性色av久久无码ai换脸| www成人国产高清内射| 精品无码国产一区二区三区51安| 久久综合色鬼综合色| 国产亚洲一卡2卡3卡4卡网站| 日本成a人片在线播放| 中文无码精品一区二区三区| 中文在线8资源库| 欧美变态另类牲交zozo| 少妇人妻大乳在线视频不卡| 精品一区二区成人精品| 国产亚洲精品精品国产亚洲综合| 邻居少妇张开双腿让我爽一夜| 欧美一区二区三区视频在线观看 | 免费无码观看的av在线播放| 日韩放荡少妇无码视频| 人妻av中文系列| 天天噜日日噜狠狠噜免费| 正在播放国产真实哭都没用| 亚洲性线免费观看视频成熟 | 国产亚洲精品俞拍视频| 人成午夜大片免费视频77777| 日产日韩亚洲欧美综合下载| 欧美 日本 国产 在线a∨观看| 成人免费无码大片a毛片| 老司机亚洲精品影院无码| 国产精品国产三级国av麻豆| 日韩精品少妇无码受不了| 国内大量偷窥精品视频| 寂寞少妇做spa按摩无码| 亚洲欧洲无码av不卡在线| 欧美3p两根一起进高清视频| 乱色熟女综合一区二区三区| 亚洲国产成人久久综合碰| 免费看国产成年无码av| 人妻av综合天堂一区| 玩弄少妇高潮ⅹxxxyw| 学生精品国产在线视频| 亚洲色无码中文字幕在线|