在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Phosducin-like protein (PDCL)

Recombinant Human Phosducin-like protein (PDCL)

  • 中文名稱：
    人PDCL重組蛋白
  • 貨號：
    CSB-YP613394HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PDCL重組蛋白
  • 貨號：
    CSB-EP613394HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PDCL重組蛋白
  • 貨號：
    CSB-EP613394HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PDCL重組蛋白
  • 貨號：
    CSB-BP613394HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PDCL重組蛋白
  • 貨號：
    CSB-MP613394HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PDCL
  • Uniprot No.：
  • 別名：
    OTTHUMP00000022069; PDCL; PHLOP1; PHLP; PHLP_HUMAN; PhLP1; Phosducin like; Phosducin like protein; Phosducin-like protein; RP11-465F21.2
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    2-301
  • 氨基酸序列
    TTLDDKLLG EKLQYYYSSS EDEDSDHEDK DRGRCAPASS SVPAEAELAG EGISVNTGPK GVINDWRRFK QLETEQREEQ CREMERLIKK LSMTCRSHLD EEEEQQKQKD LQEKISGKMT LKEFAIMNED QDDEEFLQQY RKQRMEEMRQ QLHKGPQFKQ VFEISSGEGF LDMIDKEQKS IVIMVHIYED GIPGTEAMNG CMICLAAEYP AVKFCKVKSS VIGASSQFTR NALPALLIYK GGELIGNFVR VTDQLGDDFF AVDLEAFLQE FGLLPEKEVL VLTSVRNSAT CHSEDSDLEI D
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as a positive regulator of hedgehog signaling and regulates ciliary function.; Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers.; Acts as a negative regulator of heterotrimeric G proteins assembly by trapping the preloaded G beta subunits inside the CCT chaperonin.
  • 基因功能參考文獻：
    1. PhLP1 binding stabilizes the Gbeta fold, disrupting interactions with CCT and releasing a PhLP1-Gbeta dimer for assembly with Ggamma. PMID: 25675501
    2. evidence of a generic mechanism, whereby the splicing of the PhLP gene could potentially and efficiently regulate the cellular levels of heterotrimeric G proteins. PMID: 23888055
    3. physiological control of G-protein regulation by PhLP seems to involve phosphorylation by CK2 and alternative splicing of the regulator PMID: 12466282
    4. the strong inhibitory action of PhLP(S) on Gbetagamma signaling is the result of a previously unrecognized mechanism of Gbetagamma-regulation, inhibition of Gbetagamma-folding by interference with TCP-1alpha PMID: 15745879
    5. PhLP phosphorylation permits the release of a PhLP x Gbeta intermediate from cytosolic chaperonin complex, allowing Ggamma to associate with Gbeta in this intermediate complex. PMID: 16717095
    6. cytosolic chaperonin complex-dependent mechanism exists for Gbeta5-RGS7 assembly that utilizes the co-chaperone activity of PhLP1 in a unique way PMID: 19376773
    7. PhLP-M1-G149, a Gbetagamma-interacting construct derived from phosducin-like protein 1 (PhLP) is a differential inhibitor of Gbetagamma PMID: 19403526

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell projection, cilium.
  • 蛋白家族：
    Phosducin family
  • 數據庫鏈接：

    HGNC: 8770

    OMIM: 604421

    KEGG: hsa:5082

    STRING: 9606.ENSP00000259467

    UniGene: Hs.271749



主站蜘蛛池模板： 日本一卡2卡3卡4卡免费精品| 成人做爰免费视频免费看| 免费无码一区二区三区蜜桃大| 亚洲国产成人精品无码一区二区| 香蕉在线 亚洲 欧美 专区 | 日韩毛片免费无码无毒视频观看| 亚洲人成网77777色在线播放 | 国产精品久久精品国产| 亚洲熟妇av午夜无码不卡| 欧美性狂猛xxxxx深喉| 国产免费不卡av在线播放| 亚洲欧洲中文日韩久久av乱码| 国产精品成人国产乱| 在线观看黄a∨免费无毒网站| 韩国 欧美 日产 国产精品| 少妇群交换bd高清国语版| 精品国产sm最大网站| 久久婷婷五月综合色和| 免费人成黄页在线观看国产| 久青青视频在线观看久| 69精品人人人人| 久久综合精品无码av一区二区三区 | 亚洲人成色4444在线观看| 天天做天天欢摸夜夜摸狠狠摸| 五月天天天综合精品无码| 精品久久人人爽天天玩人人妻| 亚洲爆乳无码专区www| 久久婷婷色综合老司机| 免费无码av一区二区三区| 尤物av无码色av无码| 国产aⅴ爽av久久久久久| 亚洲精品区午夜亚洲精品区| 无码国产色欲xxxx视频| 亚洲精品国产精品乱码不99| 夫前人妻被灌醉侵犯在线| 少妇的渴望hd高清在线播放| 国产乱子伦精品无码专区| 亚洲精品国产av成拍色拍个| 国产欧美在线亚洲一区| 久久av高清无码| 欧美 国产 日产 韩国 在线|