在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PDCL Antibody

PDCL Antibody

  • 中文名稱：
    PDCL兔多克隆抗體
  • 貨號：
    CSB-PA017675GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PDCL
  • 別名：
    OTTHUMP00000022069 antibody; PDCL antibody; PHLOP1 antibody; PHLP antibody; PHLP_HUMAN antibody; PhLP1 antibody; Phosducin like antibody; Phosducin like protein antibody; Phosducin-like protein antibody; RP11-465F21.2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human PDCL
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as a positive regulator of hedgehog signaling and regulates ciliary function.; Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers.; Acts as a negative regulator of heterotrimeric G proteins assembly by trapping the preloaded G beta subunits inside the CCT chaperonin.
  • 基因功能參考文獻：
    1. PhLP1 binding stabilizes the Gbeta fold, disrupting interactions with CCT and releasing a PhLP1-Gbeta dimer for assembly with Ggamma. PMID: 25675501
    2. evidence of a generic mechanism, whereby the splicing of the PhLP gene could potentially and efficiently regulate the cellular levels of heterotrimeric G proteins. PMID: 23888055
    3. physiological control of G-protein regulation by PhLP seems to involve phosphorylation by CK2 and alternative splicing of the regulator PMID: 12466282
    4. the strong inhibitory action of PhLP(S) on Gbetagamma signaling is the result of a previously unrecognized mechanism of Gbetagamma-regulation, inhibition of Gbetagamma-folding by interference with TCP-1alpha PMID: 15745879
    5. PhLP phosphorylation permits the release of a PhLP x Gbeta intermediate from cytosolic chaperonin complex, allowing Ggamma to associate with Gbeta in this intermediate complex. PMID: 16717095
    6. cytosolic chaperonin complex-dependent mechanism exists for Gbeta5-RGS7 assembly that utilizes the co-chaperone activity of PhLP1 in a unique way PMID: 19376773
    7. PhLP-M1-G149, a Gbetagamma-interacting construct derived from phosducin-like protein 1 (PhLP) is a differential inhibitor of Gbetagamma PMID: 19403526

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell projection, cilium.
  • 蛋白家族：
    Phosducin family
  • 數據庫鏈接：

    HGNC: 8770

    OMIM: 604421

    KEGG: hsa:5082

    STRING: 9606.ENSP00000259467

    UniGene: Hs.271749



主站蜘蛛池模板： 亚洲国产精品无码专区| 久欠精品国国产99国产精2021| 黑人巨大白妞出浆| 乌克兰少妇xxxx做受| 亚洲国产成人综合精品| 麻花豆传媒剧国产免费mv入口| 99视频精品国产免费观看| 免费香蕉成视频人网站| 国产午夜福利小视频合集| 九九热爱视频精品视频| 国语国产精精品国产国语清晰对话| 亚洲国产午夜精华无码福利| 国产成人a人亚洲精品无码| 国产揉捏爆乳巨胸挤奶视频| 国产精品视频观看裸模| 中字乱码视频| 色狠狠久久av五月综合| 欧美三级欧美成人高清| 日本熟妇色一本在线观看| 亚洲日本乱码中文在线电影 | 九九热久久只有精品2| 女人被男人躁得好爽免费视频| 亚洲中文字幕无码一区二区三区 | 亚洲人成网7777777国产| 久久久久国产综合av天堂| 亚洲美女高清无水av| 国语精品自产拍在线观看网站| 亚洲成av人片在线观看www| 极品嫩模高潮叫床| 特级小箩利无码毛片| av小次郎收藏| 日本护士毛茸茸高潮 | 国产999久久高清免费观看 | 极品美女扒开粉嫩小泬图片| 无码人妻一区二区三区线| 波多野结衣绝顶大高潮| 精品无码专区久久久水蜜桃 | 亚洲最新无码中文字幕久久| 老子午夜理论影院理论| 亚洲国产成人爱av在线播放| 中文字幕乱码免费专区|