在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Peroxisomal biogenesis factor 3 (PEX3), partial

  • 中文名稱:
    人PEX3重組蛋白
  • 貨號:
    CSB-YP017804HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PEX3重組蛋白
  • 貨號:
    CSB-EP017804HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PEX3重組蛋白
  • 貨號:
    CSB-BP017804HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PEX3重組蛋白
  • 貨號:
    CSB-MP017804HU1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PEX3
  • Uniprot No.:
  • 別名:
    PEX3; Peroxisomal biogenesis factor 3; Peroxin-3; Peroxisomal assembly protein PEX3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
  • 基因功能參考文獻:
    1. Thus, PEX19 and PEX3 peroxisome biogenesis factors provide an alternative posttranslational route for membrane insertion of the reticulon homology domain-containing proteins, implying that endoplasmic reticulum membrane shaping and peroxisome biogenesis may be coordinated. PMID: 29396426
    2. that newly synthesized UBXD8 is post-translationally inserted into discrete ER subdomains by a mechanism requiring cytosolic PEX19 and membrane-integrated PEX3, proteins hitherto exclusively implicated in peroxisome biogenesis PMID: 27295553
    3. This insertion of PEX3 into the ER is physiologically relevant. PMID: 26572236
    4. PEX16 mediates the peroxisomal trafficking of two distinct peroxisomal membrane proteins, PEX3 and PMP34, via the endoplasmic reticulum PMID: 25002403
    5. Thus within the cell, PEX3 is stabilized by PEX19 preventing PEX3 aggregation. PMID: 25062251
    6. Mutations in the PEX19-binding domain of PEX3 reduce the affinity for PEX19 and destabilize PEX3. PMID: 22624858
    7. The Pex19p peptide contains a characteristic motif, consisting of the leucine triad (Leu18, Leu21, Leu22), and Phe29, which are critical for the Pex3p binding and peroxisome biogenesis. PMID: 21102411
    8. The crystal structure of the cytosolic domain of PEX3 in complex with a PEX19-derived peptide. PEX3 adopts a novel fold that is best described as a large helical bundle. PMID: 20554521
    9. Interaction of PEX3 and PEX19 visualized by fluorescence resonance energy transfer (FRET). PMID: 14713233
    10. Results suggest that PEX3 plays a selective, essential, and direct role in class I peroxisomal membrane protein import as a docking factor for PEX19. PMID: 15007061
    11. Data suggest that Pex19p probably functions as a chaperone for membrane proteins and transports them to peroxisomes by anchoring to Pex3p using residues 12-73 and 40-131. PMID: 16895967
    12. either one or two tryptophan residues of Pex3p (Trp-104 and Trp-224) are directly involved in binding to Pex19p. PMID: 18174172
    13. Pex3p follows the ER-to-peroxisomal route; Pex3p requires Pex16p for ER location but is dispensable for the ER location of Pex16p PMID: 19479899
    14. The cytosolic domain of PEX3, a protein involved in the biogenesis of peroxisomes, binds membrane lipids. PMID: 19715730

    顯示更多

    收起更多

  • 相關疾病:
    Peroxisome biogenesis disorder complementation group 12 (PBD-CG12); Peroxisome biogenesis disorder 10A (PBD10A); Peroxisome biogenesis disorder 10B (PBD10B)
  • 亞細胞定位:
    Peroxisome membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Peroxin-3 family
  • 組織特異性:
    Found in all examined tissues.
  • 數據庫鏈接:

    HGNC: 8858

    OMIM: 603164

    KEGG: hsa:8504

    STRING: 9606.ENSP00000356563

    UniGene: Hs.592832



主站蜘蛛池模板: 日韩做a爰片久久毛片a片| 7777精品久久久大香线蕉| 肉感饱满中年熟妇日本| 亚洲日本乱码在线观看| 亚洲人成欧美中文字幕| 精品久久久久久无码人妻热| 国产一区二区在线影院| 在线人视频观看免费 | 小嫩妇好紧好爽18禁视频| 亚洲成av人片不卡无码| 国产免费无码一区二区| 97se狠狠狠狠狼鲁亚洲综合色| 亚洲一区二区三区无码影院| 国产精品美女久久久久久久久| 漂亮人妻被中出中文字幕| 中文字幕无码视频专区| 一线二线无人区乱码| 国产成人免费高清直播| 男人添女人囗交做爰视频| 亚洲日韩av一区二区三区四区 | 久久精品国产亚洲夜色av网站| 色94色欧美sute亚洲线路一| 国产午夜精品一区二区三区| 国产乱妇无乱码大黄aa片| 强开小婷嫩苞又嫩又紧韩国视频| 亚洲综合激情五月丁香六月| 婷婷五月小说| 人人做人人妻人人精| 人妻少妇偷人无码视频| 国产视频一区二区| 无遮挡边摸边吃奶边做视频| 国产末成年av在线播放| 精品亚洲国产成人av不卡| 国产女人和拘做受视频免费| 自拍区小说区图片区亚洲| a欧美爰片久久毛片a片| 揉着我的奶从后面进去视频| 麻豆人妻少妇精品无码专区| 亚洲综合最新无码专区| 天天狠天天添日日拍| 亚洲 欧美日韩 综合 国产|