在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (PIN4)

  • 中文名稱(chēng):
  • 貨號(hào):
    CSB-YP861478HU
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
  • 貨號(hào):
    CSB-EP861478HU
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
  • 貨號(hào):
    CSB-EP861478HU-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
  • 貨號(hào):
    CSB-BP861478HU
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
  • 貨號(hào):
    CSB-MP861478HU
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PIN4
  • Uniprot No.:
  • 別名:
    Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4; EC 5.2.1.8; Parvulin-14; Par14; hPar14; Parvulin-17; Par17; hPar17; Peptidyl-prolyl cis-trans isomerase Pin4; PPIase Pin4; Peptidyl-prolyl cis/trans isomerase EPVH; hEPVH; Rotamase Pin4; PIN4
  • 種屬:
    Homo sapiens (Human)
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Isoform 1 is involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to tightly bent AT-rich stretches of double-stranded DNA.; Isoform 2 binds to double-stranded DNA.
  • 基因功能參考文獻(xiàn):
    1. Par14 can be described as an endogenous non-histone chromatin protein, which binds DNA in vivo PMID: 25645591
    2. Ca(2+)/Calmodulin binding to the N-terminal of Par17 causes steric hindrance of the Par17 active site, thus interfering with the Par17/tubulin interaction. PMID: 25940090
    3. Data indicate that Pin1 prolyl isomerase active site cysteine, Cys113, is highly susceptible to oxidation. PMID: 25595659
    4. Data indicate the association of Par14 with insulin receptor substrate 1 (IRS-1) in human HepG2 cells overexpressing both as well as endogenously in the mouse liver. PMID: 23720771
    5. The N-terminal basic domain of human parvulin hPar14 is responsible for the entry to the nucleus and high-affinity DNA-binding. PMID: 12144781
    6. subcellular localization and DNA binding properties of hPar14 are regulated by phosphorylation of the N-terminal domain PMID: 12860119
    7. Identification of a longer Parvulin isoform (Par17) that has an extension at the 5' end including a 75 bp extended open reading frame. PMID: 16522211

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    [Isoform 1]: Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Note=Colocalizes in the nucleolus during interphase and on the spindle apparatus during mitosis with NPM1.; [Isoform 2]: Mitochondrion. Mitochondrion matrix. Note=Imported in a time- and membrane potential-dependent manner to the mitochondrial matrix, but without concomitant processing of the protein. Directed to mitochondria by a novel N-terminal domain that functions as non-cleavable mitochondrial targeting peptide.
  • 蛋白家族:
    PpiC/parvulin rotamase family, PIN4 subfamily
  • 組織特異性:
    Isoform 2 is much more stable than isoform 1 (at protein level). Ubiquitous. Isoform 1 and isoform 2 are expressed in kidney, liver, blood vessel, brain, mammary gland, skeletal muscle, small intestine and submandibularis. Isoform 1 transcripts are much m
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 8992

    OMIM: 300252

    KEGG: hsa:5303

    STRING: 9606.ENSP00000362773

    UniGene: Hs.655623



主站蜘蛛池模板: 婷婷激情综合色五月久久竹菊影视| 久久久久国精品产熟女久色| 欧美不卡无线在线一二三区观| 无码人妻丝袜视频在线播免费| 少妇人妻大乳在线视频| 国产精品自产拍在线观看| 国产性猛交普通话对白| 国产精品成人一区二区不卡| 国产亚洲精品欧洲在线观看| 久久综合亚洲色一区二区三区 | 亚洲人成电影网站在线观看 | 人人做人人爽人人爱| 亚洲αv无码一区二区三区四区 | 中国丰满熟妇xxxx性| 欧美性猛交xxxx富婆| 国产麻豆精品福利在线| 综合亚洲综合图区网友自拍| 奇米影视第4色| 三上悠亚精品一区二区久久| 国产 日韩 欧美 视频 制服| 欧美日韩不卡合集视频| 老太婆性杂交视频| 亚洲人成网亚洲欧洲无码久久| 青青青国产在线观看资源| 人妻无码熟妇乱又伦精品视频 | 少妇人妻精品一区二区三区| 免费国产黄网站在线观看视频| 99热久久这里只精品国产www| 亚洲最大av网站在线观看| 亚州av综合色区无码一区| 国产亚洲精品久久久久久久软件 | 国产乱人伦真实精品视频| 国产麻豆精品一区| 两个美女裸体舌吻互扒内裤| 国产真人作爱免费视频道歉| 色翁荡熄又大又硬又粗又动态图| 法国啄木乌av片在线播放| 午夜免费啪视频在线观看区| 亚洲性猛交xxxx| 西西444www无码大胆| 国产av久久久久精东av|