Recombinant Human Patched domain-containing protein 2 (PTCHD2), partial

中文名稱：

人DISP3重組蛋白
貨號：

CSB-YP873737HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人DISP3重組蛋白
貨號：

CSB-EP873737HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人DISP3重組蛋白
貨號：

CSB-EP873737HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人DISP3重組蛋白
貨號：

CSB-BP873737HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人DISP3重組蛋白
貨號：

CSB-MP873737HU
規(guī)格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

DISP3
Uniprot No.：

Q9P2K9
別名：

DISP3; KIAA1337; PTCHD2Protein dispatched homolog 3; Patched domain-containing protein 2
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Plays a role in neuronal proliferation and differentiation. Plays a role in the accumulation of cellular cholesterol. Involved in intracellular lipid droplet formation. May contribute to cholesterol homeostasis in neuronal cells.
基因功能參考文獻：
1. our findings imply that DISP3 may help dictate the NSC cell fate to either undergo self-renewal or switch to the terminal differentiation cell program. PMID: 28134287
2. patched domain containing 2 (PTCHD2), yielded a statistically significant P-value of 2.5 x 10(-6) (OR = 0.27) with fewer individuals classified as exhibiting symptoms of dependence to ultraviolet light, a known carcinogen, in the context of tanning PMID: 25041255
3. impact of DISP3 on the proliferation and differentiation of neural precursors PMID: 25281927
亞細胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
蛋白家族：

Patched family
組織特異性：

Expressed in brain and testis.
數據庫鏈接：

HGNC: 29251

OMIM: 611251

KEGG: hsa:57540

STRING: 9606.ENSP00000294484

UniGene: Hs.202355