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Recombinant Human Partitioning defective 6 homolog gamma (PARD6G)

  • 中文名稱:
    人PARD6G重組蛋白
  • 貨號:
    CSB-YP863155HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PARD6G重組蛋白
  • 貨號:
    CSB-EP863155HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PARD6G重組蛋白
  • 貨號:
    CSB-EP863155HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PARD6G重組蛋白
  • 貨號:
    CSB-BP863155HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PARD6G重組蛋白
  • 貨號:
    CSB-MP863155HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    PARD6G; PAR6G; Partitioning defective 6 homolog gamma; PAR-6 gamma; PAR6D
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-376
  • 氨基酸序列
    MNRSFHKSQT LRFYDCSAVE VKSKFGAEFR RFSLDRHKPG KFEDFYKLVV HTHHISNSDV TIGYADVHGD LLPINNDDNF CKAVSSANPL LRVFIQKREE AERGSLGAGS LCRRRRALGA LRDEGPRRRA HLDIGLPRDF RPVSSIIDVD LVPETHRRVR LHRHGCEKPL GFYIRDGASV RVTPHGLEKV PGIFISRMVP GGLAESTGLL AVNDEVLEVN GIEVAGKTLD QVTDMMIANS HNLIVTVKPA NQRNNVVRGG RALGSSGPPS DGTAGFVGPP APRVLQNFHP DEAESDEDND VVIEGTLEPA RPPQTPGAPA GSLSRVNGAG LAQRLQRDLA LDGGLQRLLS SLRADPRHSL ALPPGGVEEH GPAVTL
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
  • 基因功能參考文獻:
    1. This paper shows Par6G as a negative regulator of the phosphatidylinositol 3'-kinase/phosphoinositide-dependent protein kinase 1/Akt pathway and epithelial cell proliferation and evidence for frequent inactivation of Par6G gene in epithelial cancers. PMID: 26073086
    2. this study is the first to identify Par6gamma as a component of the mother centriole and to report a role of a mother centriole protein in the regulation of centrosomal protein composition. PMID: 23264737
  • 亞細胞定位:
    Cytoplasm. Cell membrane. Cell junction, tight junction.
  • 蛋白家族:
    PAR6 family
  • 組織特異性:
    Widely expressed, with a higher expression in fetal and adult kidney.
  • 數據庫鏈接:

    HGNC: 16076

    OMIM: 608976

    KEGG: hsa:84552

    STRING: 9606.ENSP00000343144

    UniGene: Hs.654920



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