在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Palmitoyltransferase ZDHHC3 (ZDHHC3), partial

  • 中文名稱:
    人ZDHHC3重組蛋白
  • 貨號:
    CSB-YP882141HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人ZDHHC3重組蛋白
  • 貨號:
    CSB-EP882141HU1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人ZDHHC3重組蛋白
  • 貨號:
    CSB-EP882141HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人ZDHHC3重組蛋白
  • 貨號:
    CSB-BP882141HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人ZDHHC3重組蛋白
  • 貨號:
    CSB-MP882141HU1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ZDHHC3
  • Uniprot No.:
  • 別名:
    ZDHHC3; HSD49; Palmitoyltransferase ZDHHC3; Acyltransferase ZDHHC3; Protein DHHC1; Zinc finger DHHC domain-containing protein 3; DHHC-3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Golgi-localized palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates. Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA. Plays an important role in G protein-coupled receptor signaling pathways involving GNAQ and potentially other heterotrimeric G proteins by regulating their dynamic association with the plasma membrane. Palmitoylates ITGA6 and ITGB4, thereby regulating the alpha-6/beta-4 integrin localization, expression and function in cell adhesion to laminin. Plays a role in the TRAIL-activated apoptotic signaling pathway most probably through the palmitoylation and localization to the plasma membrane of TNFRSF10A. In the brain, by palmitoylating the gamma subunit GABRG2 of GABA(A) receptors and regulating their postsynaptic accumulation, plays a role in synaptic GABAergic inhibitory function and GABAergic innervation. Palmitoylates the neuronal protein GAP43 which is also involved in the formation of GABAergic synapses. Palmitoylates NCDN thereby regulating its association with endosome membranes. Probably palmitoylates PRCD and is involved in its proper localization within the photoreceptor. Could mediate the palmitoylation of NCAM1 and regulate neurite outgrowth. Could palmitoylate DNAJC5 and regulate its localization to Golgi membranes. Also constitutively palmitoylates DLG4. May also palmitoylate SNAP25. Could palmitoylate the glutamate receptors GRIA1 and GRIA2 but this has not been confirmed in vivo. Could also palmitoylate the D(2) dopamine receptor DRD2.; May also function as a calcium transporter.
  • 基因功能參考文獻:
    1. DHHC3-mediated protein palmitoylation supports breast tumor growth by modulating cellular oxidative stress and senescence. PMID: 29055014
    2. HSV-1 UL20 binds to GODZ (also known as DHHC3), a Golgi apparatus-specific Asp-His-His-Cys (DHHC) zinc finger protein. a GODZ dominant-negative mutant and an inhibitor of palmitoylation reduced HSV-1 titers and altered the localization of UL20 and glycoprotein K. UL20 is palmitoylated by GODZ, and this UL20 palmitoylation is required for HSV-1 infectivity. PMID: 28724772
    3. GODZ regulates plasma membrane targeting of DR4 and thus TRAIL/DR4-mediated apoptosis in cancer cells. PMID: 22240897
    4. Palmitoylation by DHHC3 is critical for the function, expression, and stability of integrin alpha6beta4. PMID: 22314500
    5. Data conclude that GODZ encodes a Ca(2+) transport protein in addition to its ability to palmitoylate protein substrates. PMID: 19955568

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族:
    DHHC palmitoyltransferase family
  • 組織特異性:
    Widely expressed with significant expression in heart, lung, liver, skeletal muscle, kidney, testis, thymus, small intestine and leukocyte.
  • 數據庫鏈接:

    HGNC: 18470

    KEGG: hsa:51304

    UniGene: Hs.61430



主站蜘蛛池模板: 人妻少妇无码中文幕久久| 99久久精品精品6精品精品| 亚洲伊人成综合人影院青青青| 婷婷综合久久狠狠色99h| 国产精品久久久久久2021 | 久久久99精品免费观看| 最近免费中文字幕大全免费版视频| 精品国产一区二区三区av片| 骚动漫十八禁在线观看| 少妇扒开腿让我爽了一夜| 亚洲日本va午夜在线电影| 免费无码黄动漫十八禁| 综合色就爱涩涩涩综合婷婷| 日本一区二区在线播放| 亚洲国产精品综合久久网各| 国产在线一区二区在线视频| 国内精品久久人妻互换| 99久热在线精品视频观看| 99久久国语露脸精品国产色| 国产成人亚洲综合无码品善网| 精品人无码一区二区三区| 国产精品无码久久久久久久久久| 久久精品熟女亚州av麻豆| 真人一进一出120秒试看| 精品乱人伦一区二区三区 | 9420免费高清在线观看视频| 国产精品爽爽ⅴa在线观看| 国产热re99久久6国产精品首页| 人人妻人人澡人人爽人人精品浪潮 | 无码福利日韩神码福利片| 亚洲熟女精品中文字幕| 大又大粗又爽又黄少妇毛片免费| 东北老女人高潮大叫对白| 欧美深性狂猛ⅹxxx深喉| 粗大的内捧猛烈进出少妇视频| 巨乳美乳一区二区三区| www国产精品内射老师| 久久无码潮喷a片无码高潮| 波多野结衣潮喷视频无码42| 欧洲吸奶大片在线看| 欧美阿v天堂视频在99线|