在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ZDHHC3 Antibody, HRP conjugated

  • 中文名稱:
    ZDHHC3兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA882141LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) ZDHHC3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ZDHHC3
  • 別名:
    ZDHHC3; HSD49; Palmitoyltransferase ZDHHC3; Acyltransferase ZDHHC3; Protein DHHC1; Zinc finger DHHC domain-containing protein 3; DHHC-3
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Palmitoyltransferase ZDHHC3 protein (94-171AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Golgi-localized palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates. Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA. Plays an important role in G protein-coupled receptor signaling pathways involving GNAQ and potentially other heterotrimeric G proteins by regulating their dynamic association with the plasma membrane. Palmitoylates ITGA6 and ITGB4, thereby regulating the alpha-6/beta-4 integrin localization, expression and function in cell adhesion to laminin. Plays a role in the TRAIL-activated apoptotic signaling pathway most probably through the palmitoylation and localization to the plasma membrane of TNFRSF10A. In the brain, by palmitoylating the gamma subunit GABRG2 of GABA(A) receptors and regulating their postsynaptic accumulation, plays a role in synaptic GABAergic inhibitory function and GABAergic innervation. Palmitoylates the neuronal protein GAP43 which is also involved in the formation of GABAergic synapses. Palmitoylates NCDN thereby regulating its association with endosome membranes. Probably palmitoylates PRCD and is involved in its proper localization within the photoreceptor. Could mediate the palmitoylation of NCAM1 and regulate neurite outgrowth. Could palmitoylate DNAJC5 and regulate its localization to Golgi membranes. Also constitutively palmitoylates DLG4. May also palmitoylate SNAP25. Could palmitoylate the glutamate receptors GRIA1 and GRIA2 but this has not been confirmed in vivo. Could also palmitoylate the D(2) dopamine receptor DRD2.; May also function as a calcium transporter.
  • 基因功能參考文獻(xiàn):
    1. DHHC3-mediated protein palmitoylation supports breast tumor growth by modulating cellular oxidative stress and senescence. PMID: 29055014
    2. HSV-1 UL20 binds to GODZ (also known as DHHC3), a Golgi apparatus-specific Asp-His-His-Cys (DHHC) zinc finger protein. a GODZ dominant-negative mutant and an inhibitor of palmitoylation reduced HSV-1 titers and altered the localization of UL20 and glycoprotein K. UL20 is palmitoylated by GODZ, and this UL20 palmitoylation is required for HSV-1 infectivity. PMID: 28724772
    3. GODZ regulates plasma membrane targeting of DR4 and thus TRAIL/DR4-mediated apoptosis in cancer cells. PMID: 22240897
    4. Palmitoylation by DHHC3 is critical for the function, expression, and stability of integrin alpha6beta4. PMID: 22314500
    5. Data conclude that GODZ encodes a Ca(2+) transport protein in addition to its ability to palmitoylate protein substrates. PMID: 19955568

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族:
    DHHC palmitoyltransferase family
  • 組織特異性:
    Widely expressed with significant expression in heart, lung, liver, skeletal muscle, kidney, testis, thymus, small intestine and leukocyte.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 18470

    KEGG: hsa:51304

    UniGene: Hs.61430



主站蜘蛛池模板: 久久99久久99久久综合| 亚洲国产精品一区二区成人片国内| 99久久人人爽亚洲精品美女| 亚洲性啪啪无码av天堂| 美女露全乳无遮掩视频| 欧美高清性色生活片免费观看| 在线播放国产不卡免费视频| 最新高清中文字幕免费mv | 四虎国产精亚洲一区久久特色| 尤物国精品午夜福利视频| 日韩 高清 无码 人妻| av制服丝袜白丝国产网站| 搡女人真爽免费视频大全| 久久天天躁狠狠躁夜夜躁2014| 综合图区亚洲另类偷窥| 国产成人8x人网站视频| 岛国在线无码高清视频| 久久中文字幕无码专区| 无码人妻精品一区二区| 国产免费丝袜调教视频| 华人在线亚洲欧美精品| 乱码精品一区二区三区 | 亚洲欧美综合精品久久成人网| 800av凹凸视频在线观看| 国产精品无码无片在线观看| 国产精品免费一区二区三区四区| 国产精品国产亚洲区艳妇糸列短篇| 人妻.中文字幕无码| 中文字幕一区二区三区乱码| 大地资源网中文第五页| 久久综合激激的五月天| 香蕉97超级碰碰碰视频| 99精品视频免费热播在线观看| 久久丫精品忘忧草西安产品| 野狼第一精品社区| 欧美日激情日韩精品嗯| 欧美性大战xxxxx久久久√| 国产免费又色又爽粗视频| 精品夜夜澡人妻无码av蜜桃| 亚洲 欧美 成人 自拍 高清| 亚洲欧美在线一区中文字幕|